On the origin of the stabilization of the zwitterionic resting state of cysteine proteases: A theoretical study

Journal of the American Chemical Society

Volumn 130, Issue 27, 2008, Pages 8696-8705

  Mladenovic, Milena ^a   Fink, Reinhold F ^a   Thiel, Walter ^b   Schirmeister, Tanja ^a   Engels, Bernd ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITES; CATHEPSIN B; CYSTEINE PROTEASES; ION PAIRS; PROTEOLYTIC ENZYMES; PROTONATED;

AMINO ACID; AMPHOLYTE; CATHEPSIN B; CYSTEINE; CYSTEINE PROTEINASE; HISTIDINE; PAPAIN; THIOL DERIVATIVE;

ARTICLE; ENZYME ACTIVE SITE; ENZYME STABILITY; HYDROGEN BOND; MOLECULAR DYNAMICS; PROTON TRANSPORT; QUANTUM MECHANICS;

AMINO ACIDS; BINDING SITES; CATHEPSIN B; COMPUTER SIMULATION; ENZYME STABILITY; HYDROGEN BONDING; MODELS, CHEMICAL; PROTEIN STRUCTURE, SECONDARY; QUANTUM THEORY;

EID: 46949094784     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja711043x     Document Type: Article

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