Alteration of p66shc is associated with endothelial dysfunction in the abdominal aortic coarctation of rats

FEBS Letters

Volumn 582, Issue 17, 2008, Pages 2561-2566

  Lee, Sang Ki ^a   Kim, Hyo Shin ^a   Song, Yun Jeong ^a   Joo, Hee Kyoung ^a   Lee, Ji Young ^a   Lee, Kwon Ho ^a   Cho, Eun Jung ^a   Cho, Chung Hyun ^a   Park, Jin Bong ^a   Jeon, Byeong Hwa ^a  

^a Department of Physiology   (South Korea)

Author keywords

Aortic coarctation; Endothelial nitric oxide synthase; Endothelium dependent relaxation; p66shc; Superoxide

Indexed keywords

ACETYLCHOLINE; ADAPTOR PROTEIN; ANGIOTENSIN II; ENDOTHELIAL NITRIC OXIDE SYNTHASE; PROTEIN P66SHC; PROTEIN SHC; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ABDOMINAL AORTA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA COARCTATION; ARTERIAL PRESSURE; ARTICLE; BLOOD FLOW; BLOOD PRESSURE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; HEART RATE; HEMODYNAMICS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANGIOTENSIN I; ANIMALS; AORTIC COARCTATION; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; HYPERTENSION; MICE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; SUPEROXIDES;

RATTUS;

EID: 46949089832     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.06.026     Document Type: Article

References (31)

1. Madamanchi N.R., Vendrov A., and Runge M.S. Oxidative stress and vascular disease. Arterioscler. Thromb. Vasc. Biol. 25 (2005) 29-38
2. Vaziri N.D., Wang X.Q., Oveisi F., and Rad B. Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats. Hypertension 36 (2000) 142-146
3. Yu B.P. Cellular defenses against damage from reactive oxygen species. Physiol. Rev. 74 (1994) 139-162
4. Cave A.C., Brewer A.C., Narayanapanicker A., Ray R., Grieve D.J., Walker S., and Shah A.M. NADPH oxidases in cardiovascular health and disease. Antioxid. Redox Signal. 8 (2006) 691-728
5. Landmesser U., Hornig B., and Drexler H. Endothelial function: a critical determinant in atherosclerosis?. Circulation 109 (2004) II27-II33
6. Migliaccio E., Mele S., Salcini A.E., Pelicci G., Lai K.M., Superti-Furga G., Pawson T., Di Fiore P.P., Lanfrancone L., and Pelicci P.G. Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway. EMBO J. 16 (1997) 706-716
7. Migliaccio E., Giorgio M., Mele S., Pelicci G., Reboldi P., Pandolfi P.P., Lanfrancone L., and Pelicci P.G. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature 402 (1999) 309-313
8. Molavi B., and Mehta J.L. Oxidative stress in cardiovascular disease: molecular basis of its deleterious effects, its detection, and therapeutic considerations. Curr. Opin. Cardiol. 19 (2004) 488-493
9. Nemoto S., and Finkel T. Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. Science 295 (2002) 2450-2452
10. Napoli C., Martin-Padura I., de Nigris F., Giorgio M., Mansueto G., Somma P., Condorelli M., Sica G., De Rosa G., and Pelicci P. Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet. Proc. Natl. Acad. Sci. USA 100 (2003) 2112-2116
11. Camici G.G., Schiavoni M., Francia P., Bachschmid M., Martin-Padura I., Hersberger M., Tanner F.C., Pelicci P., Volpe M., Anversa P., Luscher T.F., and Cosentino F. Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress. Proc. Natl. Acad. Sci. USA 104 (2007) 5217-5222
12. Yamamori T., White A.R., Mattagajasingh I., Khanday F.A., Haile A., Qi B., Jeon B.H., Bugayenko A., Kasuno K., Berkowitz D.E., and Irani K. P66shc regulates endothelial NO production and endothelium-dependent vasorelaxation: implications for age-associated vascular dysfunction. J. Mol. Cell. Cardiol. 39 (2005) 992-995
13. Lee S.K., Kim Y.S., Kim C.S., Son S.J., Yoo D.G., Lee K.H., Lee S.D., Park J.B., and Jeon B.H. p66shc adaptor protein suppresses the activation of endothelial nitric oxide synthase in mouse embryonic fibroblasts. Korean J. Physiol. Pharmacol. 10 (2006) 155-159
14. Fernandes M., Onesti G., Weder A., Dykyj R., Gould A.B., Kim K.E., and Swartz C. Experimental model of severe renal hypertension. J. Lab. Clin. Med. 87 (1976) 561-567
15. Parker Jr. F.B., Streeten D.H., Farrell B., Blackman M.S., Sondheimer H.M., and Anderson Jr. G.H. Preoperative and postoperative renin levels in coarctation of the aorta. Circulation 66 (1982) 513-514
16. Barton C.H., Ni Z., and Vaziri N.D. Enhanced nitric oxide inactivation in aortic coarctation-induced hypertension. Kidney Int. 60 (2001) 1083-1087
17. Sindhu R.K., Roberts C.K., Ehdaie A., Zhan C.D., and Vaziri N.D. Effects of aortic coarctation on aortic antioxidant enzymes and NADPH oxidase protein expression. Life Sci. 76 (2005) 945-953
18. Vaziri N.D., and Ni Z. Expression of NOX-I, gp91phox, p47phox and P67phox in the aorta segments above and below coarctation. Biochim. Biophys. Acta 1723 (2005) 321-327
19. Ungvari Z., Csiszar A., Kaminski P.M., Wolin M.S., and Koller A. Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system. Am. J. Pathol. 165 (2004) 219-226
20. Rajagopalan S., Kurz S., Munzel T., Tarpey M., Freeman B.A., Griendling K.K., and Harrison D.G. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J. Clin. Invest. 97 (1996) 1916-1923
21. Zhou M.S., Jaimes E.A., and Raij L. Vascular but not cardiac remodeling is associated with superoxide production in angiotensin II hypertension. J. Hypertens. 23 (2005) 1737-1743
22. Li J., Zhao X., Li X., Lerea K.M., and Olson S.C. Angiotensin II type 2 receptor-dependent increases in nitric oxide synthase expression in the pulmonary endothelium is mediated via a G alpha i3/Ras/Raf/MAPK pathway. Am. J. Physiol.: Cell Physiol. 292 (2007) C2185-C2196
23. Rojo-Ortega J.M., and Genest J. A method for production of experimental hypertension in rats. Can. J. Physiol. Pharmacol. 46 (1968) 883-885
24. Jeon B.H., Gupta G., Park Y.C., Qi B., Haile A., Khanday F.A., Liu Y.X., Kim J.M., Ozaki M., White A.R., Berkowitz D.E., and Irani K. Apurinic/apyrimidinic endonuclease 1 regulates endothelial NO production and vascular tone. Circ. Res. 95 (2004) 902-910
25. Yayama K., Horii M., Hiyoshi H., Takano M., Okamoto H., Kagota S., and Kunitomo M. Up-regulation of angiotensin II type 2 receptor in rat thoracic aorta by pressure-overload. J. Pharmacol. Exp. Ther. 308 (2004) 736-743
26. Goetz R.M., and Holtz J. Enhanced angiotensin-converting enzyme activity and impaired endothelium-dependent vasodilation in aortae from hypertensive rats: evidence for a causal link. Clin. Sci. (Lond.) 97 (1999) 165-174
27. Bell D.R. Vascular smooth muscle responses to endothelial autacoids in rats with chronic coarctation hypertension. J. Hypertens. 11 (1993) 65-74
28. Dancu M.B., Berardi D.E., Vanden Heuvel J.P., and Tarbell J.M. Asynchronous shear stress and circumferential strain reduces endothelial NO synthase and cyclooxygenase-2 but induces endothelin-1 gene expression in endothelial cells. Arterioscler. Thromb. Vasc. Biol. 24 (2004) 2088-2094
29. Francia P., delli Gatti C., Bachschmid M., Martin-Padura I., Savoia C., Migliaccio E., Pelicci P.G., Schiavoni M., Luscher T.F., Volpe M., and Cosentino F. Deletion of p66shc gene protects against age-related endothelial dysfunction. Circulation 110 (2004) 2889-2895
30. Prado C.M., Ramos S.G., Alves-Filho J.C., Elias Jr. J., Cunha F.Q., and Rossi M.A. Turbulent flow/low wall shear stress and stretch differentially affect aorta remodeling in rats. J. Hypertens. 24 (2006) 503-515
31. Bardy N., Merval R., Benessiano J., Samuel J.L., and Tedgui A. Pressure and angiotensin II synergistically induce aortic fibronectin expression in organ culture model of rabbit aorta. Evidence for a pressure-induced tissue renin-angiotensin system. Circ. Res. 79 (1996) 70-78