Up-Regulation of Angiotensin II Type 2 Receptor in Rat Thoracic Aorta by Pressure-Overload

Journal of Pharmacology and Experimental Therapeutics

Volumn 308, Issue 2, 2004, Pages 736-743

  Yayama, Katsutoshi ^a   Horii, Miyuki ^a   Hiyoshi, Hiromi ^a   Takano, Masaoki ^a   Okamoto, Hiroshi ^a   Kagota, Satomi ^b   Kunitomo, Masaru ^b  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b MUKOGAWA WOMEN'S UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; CANDESARTAN; CYCLIC GMP; LOSARTAN; MESSENGER RNA; N(G) NITROARGININE METHYL ESTER;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; GENETICS; HYPERTENSION; MALE; METABOLISM; NONHUMAN; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PRESSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THORACIC AORTA; UPREGULATION; VASCULAR ENDOTHELIUM; VASCULAR RING; VASOCONSTRICTION;

ANGIOTENSIN II; ANIMALS; AORTA, THORACIC; BLOOD PRESSURE; ENDOTHELIUM, VASCULAR; MALE; PRESSURE; RATS; RATS, WISTAR; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RNA, MESSENGER; UP-REGULATION; VASOCONSTRICTION;

EID: 1642457221     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.058420     Document Type: Article

References (32)

1. Akishita M, Yamada H, Dzau VJ, and Horiuchi M (1999) Increased vasoconstrictor response of the mouse lacking angiotensin II type 2 receptor. Biochem Biophys Res Commun 261:345-349.
2. Baker KM, Chernin MI, Wixson SK, and Aceto JF (1990) Renin-angiotensin system involvement in pressure-overload cardiac hypertrophy in rats. Am J Physiol 259:H324-H332.
3. 1, receptor antagonist in hypertensive rats. Hypertension 34:1112-1116.
4. Bardy N, Merval R, Benessiano J, Samuel JL, and Tedgui A (1996) Pressure and angiotensin II synergistically induce aortic fibronectin expression in organ culture model of rabbit aorta. Evidence for a pressure-induced tissue renin-angiotensin system. Cir Res 79:70-78.
5. Barton CH, Ni Z, and Vaziri ND (2001) Effect of severe aortic banding above the renal arteries on nitric oxide synthase isotype expression. Kidney Int 59:654-661.
6. Bonnet F, Cooper ME, Carey RM, Casley D, and Cao Z (2001) Vascular expression of angiotensin type 2 receptor in the adult rat: influence of angiotensin II infusion. J Hypertens 19:1075-1081.
7. Bouloumie A, Bauersachs J, Linz W, Scholkens BA, Wiemer G, and Freming BR (1997) Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and superoxide anion production. Hypertension 30:934-941.
8. 2 receptor in blood pressure regulation and therapeutic implications. Am J Hypertens 14;98S-102S.
9. 2) receptor in the regulation of blood pressure and renal function. Hypertension 35:155-163.
10. de Gasparo M, Catt KJ, Inagami T, Wright W, and Unger TH (2000) International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev 52:415-472.
11. Doggrell SA and Brown L (1998) Rat models of hypertension, cardiac hypertrophy and failure. Cardiovasc Res 39:89-105.
12. 2-subtype receptors in the blood pressure-lowering effects of losartan in salt-restricted rats. J Hypertens 16:2039-2043.
13. 2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism. Hypertension 31:349-355.
14. Gyurko R, Kimura B, Kurian P, Crews FT, and Phillips MI (1992) Angiotensin II receptor subtypes play opposite roles in regulating phosphatidylinositol hydrolysis in rat skin slices. Biochem Biophys Res Commun 186:285-292.
15. Hein L, Barsh GS, Pratt RE, Dzau VJ, and Kobilka BK (1995) Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice. Nature (Lond) 377:744-747.
16. Hutchinson HG, Hein L, Fujinaga M, and Pratt RE (1999) Modulation of vascular development and injury by angiotensin II. Cardiovasc Res 41:689-700.
17. Ichiki T, Labosky PA, Shiota C, Okuyama S, Imagawa Y, Fogo A, Niimura F, Ichikawa I, Hogan BL, and Inagami T (1995) Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor. Nature (Lond) 377:748-750.
18. 2 receptor-dependent vasodilation is mediated by activation of vascular kinin generation under flow conditions. Br J Pharmacol 136:484-491.
19. Liu Y, Yang X, Sharov VG, Nass O, Sabbah HN, Peterson E, and Carretero OA (1997) Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure: role of kinins and angiotensin II type 2 receptors. J Clin Investig 99:1926-1935.
20. Noda M, Katoh T, Takuwa N, Kumada M, Kurokawa K, and Takuwa Y (1994) Synergistic stimulation of parathyroid hormone-related peptide gene expression by mechanical stretch and angiotensin II in rat aortic smooth muscle cells. J Biol Chem 269:17911-17917.
21. Nouet S and Nahmias C (2000) Signal transduction from the angiotensin II AT2 receptor. Trends Endocrinol Metab 11:1-6.
22. Ohtani R, Ohashi Y, Muranaga K, Itoh N, and Okamoto H (1989) Changes in activity of the renin-angiotensin system of the rat by induction of acute inflammation. Life Sci 44:237-241.
23. Otsuka S, Sugano M, Makino N, Sawada S, Hata T, and Niho Y (1998) Interaction of mRNAs for angiotensin II type 1 and type 2 receptors to vascular remodeling in spontaneously hypertensive rats. Hypertension 32:467-472.
24. Scheuer DA and Perrone MH (1993) Angiotensin type 2 receptors mediate depressor phase of biphasic pressure response to angiotensin. Am J Physiol 264:R917-R923.
25. Seyedi N, Xu X, Nasjletti A, and Hintze TH (1995) Coronary kinin generation mediates nitric oxide release after angiotensin receptor stimulation. Hypertension 26:164-170.
26. 2 receptor in a renal wrap hypertension model. Hypertension 33:1237-1242.
27. 2 receptors in angiotensin II-stimulated contraction of small mesenteric arteries in young SHR. Hypertension 33:366-372.
28. Tsutsumi Y, Matsubara H, Masaki H, Kurihara H, Murasawa S, Takai S, Miyazaki M, Nozawa Y, Ozono R, Nakagawa K, et al. (1999) Angiotendin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation. J Clin Investig 104:925-935.
29. Viswanathan M, Tsutsumi K, Correa FMA, and Saavedra JM (1991) Changes in expression of angiotensin receptor subtypes in the rat aorta during development. Biochem Biophys Res Commun 179:1361-1367.
30. Wirth KJ, Linz W, Wiemer G, and Scholkens BA (1996) Differences in acetylcholine-and bradykinin-induced vasorelaxation of the mesenteric vascular bed in spontaneously hypertensive rats of different ages. Naunyn-Schmiedeberg's Arch Pharmacol 354:38-43.
31. 2-receptor mRNA in the heart in pressure-overload cardiac hypertrophy in the rat. Biochem Pharmacol 65:1017-1025.
32. 2 and arachidonic acid. J Neurosci 18:679-686.