Asynchronous shear stress and circumferential strain reduces endothelial NO synthase and cyclooxygenase-2 but induces endothelin-1 gene expression in endothelial cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 24, Issue 11, 2004, Pages 2088-2094

  Dancu, Michael B ^a,b   Berardi, Danielle E ^a   Vanden Heuvel, John P ^a   Tarbell, John M ^b  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b City University of New York   (United States)

Author keywords

Coronary arteries; COX 2; eNOS; ET 1; Hemodynamics; Shear stress and strain

Indexed keywords

CYCLOOXYGENASE 2; ENDOTHELIN 1; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROSTACYCLIN; VASOACTIVE AGENT;

ANIMAL CELL; ARTERY INTIMA PROLIFERATION; ARTICLE; ATHEROGENESIS; BLOOD VESSEL TONE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME SYNTHESIS; GENE EXPRESSION; HEMODYNAMICS; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHEAR STRESS; THROMBOCYTE ADHESION;

ANIMALS; AORTA; CATTLE; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CYCLOOXYGENASE 2; ENDOTHELIAL CELLS; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEMODYNAMIC PROCESSES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; STRESS, MECHANICAL; TIME FACTORS;

EID: 8344263796     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000143855.85343.0e     Document Type: Article

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