2-Aminobenzophenones as a novel class of bradykinin B1 receptor antagonists

Journal of Medicinal Chemistry

Volumn 51, Issue 13, 2008, Pages 3946-3952

  Su, Dai Shi ^a   Lim, John L ^a   Tinney, Elizabeth ^a   Wan, Bang Lin ^a   Murphy, Kathy L ^a   Reiss, Duane R ^a   Harrell, C Meacham ^a   O'Malley, Stacy S ^a   Ransom, Rick W ^a   Chang, Raymond S L ^a   Pettibone, Douglas J ^a   Yu, Jian ^a   Tang, Cuyue ^a   Prueksaritanont, Thomayant ^a   Freidinger, Roger M ^a   Bock, Mark G ^a   Anthony, Neville J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOBENZOPHENONE DERIVATIVE; 4 AMINO N (2 BENZOYLPHENYL)BENZENESULFONAMIDE; BENZOPHENONE DERIVATIVE; BRADYKININ B1 RECEPTOR ANTAGONIST; TETRAHYDROFURAN 2 YLMETHYL 4 [[(2 BENZOYLPHENYL)AMINO]SULFONYL]PHENYLCARBAMATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DOG; DRUG BIOAVAILABILITY; DRUG METABOLISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HUMAN; HUMAN CELL; INFLAMMATION; NONHUMAN; PAIN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; RECEPTOR OCCUPANCY; SPRAGUE DAWLEY RAT; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TRANSGENIC RAT;

AMINES; ANIMALS; BENZOPHENONES; CELL LINE; DOGS; HUMANS; MOLECULAR STRUCTURE; RATS; RECEPTOR, BRADYKININ B1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 46849121569     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm800199h     Document Type: Article

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