Generation and characterization of a human bradykinin receptor B1 transgenic rat as a pharmacodynamic model

Journal of Pharmacology and Experimental Therapeutics

Volumn 310, Issue 2, 2004, Pages 488-497

  Hess, J Fred ^a   Ransom, Richard W ^a   Zeng, Zhizhen ^a   Chang, Raymond S L ^a   Hey, Patricia J ^a   Warren, Lee ^a   Harrell, Charles M ^a   Murphy, Kathryn L ^a   Chen, Tsing Bau ^a   Miller, Patricia J ^a   Lis, Edward ^a   Reiss, Duane ^a   Gibson, Raymond E ^a   Markowitz, M Kristine ^a   DiPardo, Robert M ^a   Su, Dai Shi ^a   Bock, Mark G ^a   Gould, Robert J ^a   Pettibone, Douglas J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ B1 RECEPTOR; ENOLASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN HOMOGENATE; CENTRAL NERVOUS SYSTEM; CHROMOSOME 1; CONTROLLED STUDY; FEMALE; GENE INSERTION; GENE MAPPING; HETEROZYGOSITY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MALE; MEMBRANE; NEUROPATHIC PAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PHARMACODYNAMICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SPECIES; SPINAL CORD; TISSUE SLICE; TRANSGENE; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BRAIN; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; ILEUM; MALE; MODELS, ANIMAL; PEPTIDE FRAGMENTS; PROTEIN BINDING; RATS; RECEPTOR, BRADYKININ B1;

EID: 3342877436     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.066886     Document Type: Article

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