-
1
-
-
38349171887
-
Oral delivery of antisense oligonucleotides in man
-
Tillman LG, Geary RS, Hardee GE. Oral delivery of antisense oligonucleotides in man. J Pharm Sci 2008; 97: 225-236
-
(2008)
J Pharm Sci
, vol.97
, pp. 225-236
-
-
Tillman, L.G.1
Geary, R.S.2
Hardee, G.E.3
-
2
-
-
0005772676
-
Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide
-
Stephenson ML, Zamecnik PC. Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc Natl Acad Sci USA 1978; 75: 285-288
-
(1978)
Proc Natl Acad Sci USA
, vol.75
, pp. 285-288
-
-
Stephenson, M.L.1
Zamecnik, P.C.2
-
3
-
-
0345570537
-
Characterization of oligonucleotide transport into living cells
-
Loke SL, Stein CA, Zhang XH et al. Characterization of oligonucleotide transport into living cells. Proc Natl Acad Sci USA 1989; 86: 3474-3478
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 3474-3478
-
-
Loke, S.L.1
Stein, C.A.2
Zhang, X.H.3
-
4
-
-
9644255578
-
Connective tissue growth factor regulates the key events in tubular epithelial to myofibroblast transition in vitro
-
Zhang C, Meng X, Zhu Z et al. Connective tissue growth factor regulates the key events in tubular epithelial to myofibroblast transition in vitro. Cell Biol Int 2004; 28: 863-873
-
(2004)
Cell Biol Int
, vol.28
, pp. 863-873
-
-
Zhang, C.1
Meng, X.2
Zhu, Z.3
-
5
-
-
0033849626
-
Role of Ras isoforms in the stimulated proliferation of human renal fibroblasts in primary culture
-
Sharpe CC, Dockrell ME, Noor MI et al. Role of Ras isoforms in the stimulated proliferation of human renal fibroblasts in primary culture. J Am Soc Nephrol 2000; 11: 1600-1606
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 1600-1606
-
-
Sharpe, C.C.1
Dockrell, M.E.2
Noor, M.I.3
-
6
-
-
0030000245
-
Progress in antisense oligonucleotide therapeutics
-
Crooke ST, Bennett CF. Progress in antisense oligonucleotide therapeutics. Annu Rev Pharmacol Toxicol 1996; 36: 107-129
-
(1996)
Annu Rev Pharmacol Toxicol
, vol.36
, pp. 107-129
-
-
Crooke, S.T.1
Bennett, C.F.2
-
7
-
-
0032575323
-
Correlating structure and stability of DNA duplexes with incorporated 2′-O-modified RNA analogues
-
Tereshko V, Portmann S, Tay EC et al. Correlating structure and stability of DNA duplexes with incorporated 2′-O-modified RNA analogues. Biochemistry 1998; 37: 10626-10634
-
(1998)
Biochemistry
, vol.37
, pp. 10626-10634
-
-
Tereshko, V.1
Portmann, S.2
Tay, E.C.3
-
8
-
-
0028241377
-
Biodistribution and metabolism of internally 3H-labeled oligonucleotides: I. Comparison of a phosphodiester and a phosphorothioate
-
Sands H, Gorey-Feret LJ, Cocuzza AJ et al. Biodistribution and metabolism of internally 3H-labeled oligonucleotides: I. Comparison of a phosphodiester and a phosphorothioate. Mol Pharmacol 1994; 45: 932-943
-
(1994)
Mol Pharmacol
, vol.45
, pp. 932-943
-
-
Sands, H.1
Gorey-Feret, L.J.2
Cocuzza, A.J.3
-
9
-
-
0029031695
-
Transport of phosphorothioate oligonucleotides in kidney: Implications formolecular therapy
-
Rappaport J, Hanss B, Kopp JB et al. Transport of phosphorothioate oligonucleotides in kidney: implications formolecular therapy. Kidney Int 1995; 47: 1462-1469
-
(1995)
Kidney Int
, vol.47
, pp. 1462-1469
-
-
Rappaport, J.1
Hanss, B.2
Kopp, J.B.3
-
10
-
-
0034000915
-
Effects of ICAM-1 antisense oligonucleotide on the tubulointerstitium in mice with unilateral ureteral obstruction
-
Cheng QL, Chen XM, Li F et al. Effects of ICAM-1 antisense oligonucleotide on the tubulointerstitium in mice with unilateral ureteral obstruction. Kidney Int 2000; 57: 183-190
-
(2000)
Kidney Int
, vol.57
, pp. 183-190
-
-
Cheng, Q.L.1
Chen, X.M.2
Li, F.3
-
11
-
-
20044394365
-
Methoxyethyl-modified intercellular adhesion molecule-1 antisense phosphorothiateoligonucleotides inhibit allograft rejection, ischemic-reperfusion injury, and cyclosporine-induced nephrotoxicity
-
Chen W, Langer RM, Janczewska S et al. Methoxyethyl-modified intercellular adhesion molecule-1 antisense phosphorothiateoligonucleotides inhibit allograft rejection, ischemic-reperfusion injury, and cyclosporine-induced nephrotoxicity. Transplantation 2005; 79: 401-408
-
(2005)
Transplantation
, vol.79
, pp. 401-408
-
-
Chen, W.1
Langer, R.M.2
Janczewska, S.3
-
12
-
-
35248841125
-
Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes
-
Guha M, Xu ZG, Tung D et al. Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes. Faseb J 2007; 21: 3355-3368
-
(2007)
Faseb J
, vol.21
, pp. 3355-3368
-
-
Guha, M.1
Xu, Z.G.2
Tung, D.3
-
13
-
-
2542473312
-
Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis
-
Yokoi H, Mukoyama M, Nagae T et al. Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis. J Am Soc Nephrol 2004; 15: 1430-1440
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1430-1440
-
-
Yokoi, H.1
Mukoyama, M.2
Nagae, T.3
-
14
-
-
21144449335
-
Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis
-
Yamada M, Katsuma S, Adachi T et al. Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis. Proc Natl Acad Sci USA 2005; 102: 7736-7741
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 7736-7741
-
-
Yamada, M.1
Katsuma, S.2
Adachi, T.3
-
16
-
-
0033736396
-
Transforming growth factor-beta 1 antisense oligodeoxynucleotides block interstitial fibrosis in unilateral ureteral obstruction
-
Isaka Y, Tsujie M, Ando Y et al. Transforming growth factor-beta 1 antisense oligodeoxynucleotides block interstitial fibrosis in unilateral ureteral obstruction. Kidney Int 2000; 58: 1885-1892
-
(2000)
Kidney Int
, vol.58
, pp. 1885-1892
-
-
Isaka, Y.1
Tsujie, M.2
Ando, Y.3
-
17
-
-
0037255325
-
Oligodeoxynucleotide studies in primates: Antisense and immune stimulatory indications
-
Farman CA, Kornbrust DJ. Oligodeoxynucleotide studies in primates: antisense and immune stimulatory indications. Toxicol Pathol 2003; 31(Suppl): 119-122
-
(2003)
Toxicol Pathol
, vol.31
, Issue.SUPPL.
, pp. 119-122
-
-
Farman, C.A.1
Kornbrust, D.J.2
-
18
-
-
0032697942
-
A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides
-
Levin AA. A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides. Biochim Biophys Acta 1999; 1489: 69-84
-
(1999)
Biochim Biophys Acta
, vol.1489
, pp. 69-84
-
-
Levin, A.A.1
-
20
-
-
0001359591
-
Introduction of a Chimeric Chalcone Synthase gene into Petunia results in reversible co-suppression of homologous genes in trans
-
Napoli C, Lemieux C, Jorgensen R. Introduction of a Chimeric Chalcone Synthase gene into Petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 1990; 2: 279-289
-
(1990)
Plant Cell
, vol.2
, pp. 279-289
-
-
Napoli, C.1
Lemieux, C.2
Jorgensen, R.3
-
21
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
-
22
-
-
0037123601
-
Ancient pathways programmed by small RNAs
-
Zamore PD. Ancient pathways programmed by small RNAs. Science 2002; 296: 1265-1269
-
(2002)
Science
, vol.296
, pp. 1265-1269
-
-
Zamore, P.D.1
-
23
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411: 494-498
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
-
24
-
-
34248682403
-
RNAi therapeutics: Principles, prospects and challenges
-
Aagaard L, Rossi JJ. RNAi therapeutics: principles, prospects and challenges. Adv Drug Deliv Rev 2007; 59: 75-86
-
(2007)
Adv Drug Deliv Rev
, vol.59
, pp. 75-86
-
-
Aagaard, L.1
Rossi, J.J.2
-
25
-
-
33646188259
-
3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets
-
Birmingham A, Anderson EM, Reynolds A et al. 3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets. Nat Methods 2006; 3: 199-204
-
(2006)
Nat Methods
, vol.3
, pp. 199-204
-
-
Birmingham, A.1
Anderson, E.M.2
Reynolds, A.3
-
26
-
-
1942533474
-
In vivo activity of nuclease-resistant siRNAs
-
Layzer JM, McCaffrey AP, Tanner AK et al. In vivo activity of nuclease-resistant siRNAs. RNA 2004; 10: 766-771
-
(2004)
RNA
, vol.10
, pp. 766-771
-
-
Layzer, J.M.1
McCaffrey, A.P.2
Tanner, A.K.3
-
27
-
-
16244362066
-
Cationic lipids enhance siRNA-mediated interferon response in mice
-
Ma Z, Li J, He F et al. Cationic lipids enhance siRNA-mediated interferon response in mice. Biochem Biophys Res Commun 2005; 330: 755-759
-
(2005)
Biochem Biophys Res Commun
, vol.330
, pp. 755-759
-
-
Ma, Z.1
Li, J.2
He, F.3
-
28
-
-
20144389695
-
Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7
-
Hornung V, Guenthner-Biller M, Bourquin C et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med 2005; 11: 263-270
-
(2005)
Nat Med
, vol.11
, pp. 263-270
-
-
Hornung, V.1
Guenthner-Biller, M.2
Bourquin, C.3
-
29
-
-
13444262170
-
Inhibition of respiratory viruses by nasally administered siRNA
-
Bitko V, Musiyenko A, Shulyayeva O et al. Inhibition of respiratory viruses by nasally administered siRNA. Nat Med 2005; 11: 50-55
-
(2005)
Nat Med
, vol.11
, pp. 50-55
-
-
Bitko, V.1
Musiyenko, A.2
Shulyayeva, O.3
-
30
-
-
0038748037
-
Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model
-
Reich SJ, Fosnot J, Kuroki A et al. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. Mol Vis 2003; 9: 210-216
-
(2003)
Mol Vis
, vol.9
, pp. 210-216
-
-
Reich, S.J.1
Fosnot, J.2
Kuroki, A.3
-
31
-
-
6944238701
-
Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury
-
Hamar P, Song E, Kokeny G et al. Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury. Proc Natl Acad Sci USA 2004; 101: 14883-14888
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 14883-14888
-
-
Hamar, P.1
Song, E.2
Kokeny, G.3
-
32
-
-
33745350487
-
TGF-beta1 siRNA suppresses the tubulointerstitial fibrosis in the kidney of ureteral obstruction
-
Hwang M, Kim HJ, Noh HJ et al. TGF-beta1 siRNA suppresses the tubulointerstitial fibrosis in the kidney of ureteral obstruction. Exp Mol Pathol 2006; 81: 48-54
-
(2006)
Exp Mol Pathol
, vol.81
, pp. 48-54
-
-
Hwang, M.1
Kim, H.J.2
Noh, H.J.3
-
33
-
-
21344454891
-
Exploring RNA interference as a therapeutic strategy for renal disease
-
Takabatake Y, Isaka Y, Mizui M et al. Exploring RNA interference as a therapeutic strategy for renal disease. Gene Ther 2005; 12: 965-973
-
(2005)
Gene Ther
, vol.12
, pp. 965-973
-
-
Takabatake, Y.1
Isaka, Y.2
Mizui, M.3
-
34
-
-
32944454941
-
Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo
-
Judge AD, Bola G, Lee AC et al. Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo. Mol Ther 2006; 13: 494-505
-
(2006)
Mol Ther
, vol.13
, pp. 494-505
-
-
Judge, A.D.1
Bola, G.2
Lee, A.C.3
|