메뉴 건너뛰기




Volumn 7, Issue SUPPL. 1, 2006, Pages

Integration of enzyme kinetic models and isotopomer distribution analysis for studies of in situ cell operation

Author keywords

[No Author keywords available]

Indexed keywords

ISOTOPE; ISOTOPOMER; TRACER;

EID: 46749150489     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-7-S1-S7     Document Type: Review
Times cited : (10)

References (49)
  • 1
    • 4243829380 scopus 로고    scopus 로고
    • Bidirectional Reaction Steps in Metabolic Networks: IV. Optimal Design of Isotopomer Labeling Experiments
    • 10.1002/(SICI)1097-0290(1999)66:2<86::AID-BIT2>3.0.CO;2-A 10567067
    • Mollney M Wiechert W Kownatzki D de Graaf AA Bidirectional Reaction Steps in Metabolic Networks: IV. Optimal Design of Isotopomer Labeling Experiments Biotechnol Bioeng 1999, 66:86-103 10.1002/ (SICI)1097-0290(1999)66:2<86::AID-BIT2>3.0.CO;2-A 10567067
    • (1999) Biotechnol Bioeng , vol.66 , pp. 86-103
    • Mollney, M.1    Wiechert, W.2    Kownatzki, D.3    de Graaf, A.A.4
  • 2
    • 0030050268 scopus 로고    scopus 로고
    • Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolic balancing
    • 10.1002/(SICI)1097-0290(19960120)49:2<111::AID-BIT1>3.0.CO;2-T
    • Marx A de Graaf AA Wiechert W Eggeling L Sahm H Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolic balancing Biotechnol Bioenerg 1996, 49:111-129 10.1002/ (SICI)1097-0290(19960120)49:2<111::AID-BIT1>3.0.CO;2-T
    • (1996) Biotechnol Bioenerg , vol.49 , pp. 111-129
    • Marx, A.1    de Graaf, A.A.2    Wiechert, W.3    Eggeling, L.4    Sahm, H.5
  • 4
    • 0025924769 scopus 로고
    • 13C-NMR: A simple yet comprehensive method for analysis of intermediary metabolism
    • 10.1016/0968-0004(91)90004-F 2053137
    • Jeffrey FM Rajagopal A Malloy CR Sherry AD 13C-NMR: A simple yet comprehensive method for analysis of intermediary metabolism Trends Biochem Sci 1991, 16:5-10 10.1016/0968-0004(91)90004-F 2053137
    • (1991) Trends Biochem Sci , vol.16 , pp. 5-10
    • Jeffrey, F.M.1    Rajagopal, A.2    Malloy, C.R.3    Sherry, A.D.4
  • 5
    • 0029146299 scopus 로고
    • Biosynthetically directed fractional 13C-labeling of proteinogenic amino acids - An efficient analytical tool to investigate intermediary metabolism
    • 10.1111/j.1432-1033.1995.tb20829.x 7556192
    • Szyperski T Biosynthetically directed fractional 13C-labeling of proteinogenic amino acids - an efficient analytical tool to investigate intermediary metabolism Eur J Biochem 1995, 232:433-448 10.1111/ j.1432-1033.1995.tb20829.x 7556192
    • (1995) Eur J Biochem , vol.232 , pp. 433-448
    • Szyperski, T.1
  • 6
    • 0347918847 scopus 로고    scopus 로고
    • Toward dynamic isotopomer analysis in the rat brain in Vivo: Automatic quantitation of 13C NMR spectra using LCModel
    • 10.1002/nbm.840 14679502
    • Henry PG Oz G Provencher S Gruetter R Toward dynamic isotopomer analysis in the rat brain in vivo: Automatic quantitation of 13C NMR spectra using LCModel NMR Biomed 2003, 16:400-412 10.1002/nbm.840 14679502
    • (2003) NMR Biomed , vol.16 , pp. 400-412
    • Henry, P.G.1    Oz, G.2    Provencher, S.3    Gruetter, R.4
  • 7
    • 0026204952 scopus 로고
    • Mass isotopomer analysis: Theoretical and practical considerations
    • 10.1002/bms.1200200804
    • Lee W-NP Byerley LO Bergner EA Edmond J Mass isotopomer analysis: theoretical and practical considerations BiolMass Spect 1991, 20:451-458 10.1002/bms.1200200804
    • (1991) BiolMass Spect , vol.20 , pp. 451-458
    • Lee, W.-N.P.1    Byerley, L.O.2    Bergner, E.A.3    Edmond, J.4
  • 8
    • 1642538406 scopus 로고    scopus 로고
    • High-throughput metabolic flux analysis based on gas chromatography-mass spectrometry derived 13C constraints
    • 10.1016/j.ab.2003.10.036 14751266
    • Fischer E Zamboni N Sauer U High-throughput metabolic flux analysis based on gas chromatography-mass spectrometry derived 13C constraints Analytical Biochemistry 2004, 325:308-316 10.1016/j.ab.2003.10.036 14751266
    • (2004) Analytical Biochemistry , vol.325 , pp. 308-316
    • Fischer, E.1    Zamboni, N.2    Sauer, U.3
  • 9
    • 0038650885 scopus 로고    scopus 로고
    • In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: Implications for brain function
    • 10.1146/annurev.physiol.65.092101.142131 12524459
    • Rothman DL Behar KL Hyder F Shulman RG In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: Implications for brain function Annu Rev Physiol 2003, 65:401-427 10.1146/ annurev.physiol.65.092101.142131 12524459
    • (2003) Annu Rev Physiol , vol.65 , pp. 401-427
    • Rothman, D.L.1    Behar, K.L.2    Hyder, F.3    Shulman, R.G.4
  • 11
    • 0025923743 scopus 로고
    • 13C NMR for the assessment of human brain glucose metabolism in vivo
    • 10.1021/bi00240a002 2054342
    • Beckmann N Turkalj I Seelig J Keller U 13C NMR for the assessment of human brain glucose metabolism in vivo Biochemistry 1991, 30:6362-6366 10.1021/bi00240a002 2054342
    • (1991) Biochemistry , vol.30 , pp. 6362-6366
    • Beckmann, N.1    Turkalj, I.2    Seelig, J.3    Keller, U.4
  • 12
    • 0035065635 scopus 로고    scopus 로고
    • 1-(13)C glucose magnetic resonance spectroscopy of pediatric and adult brain disorders
    • 10.1002/nbm.679 11252037
    • Bluml S Moreno A Hwang JH Ross BD 1-(13)C glucose magnetic resonance spectroscopy of pediatric and adult brain disorders NMR Biomed 2001, 14:19-32 10.1002/nbm.679 11252037
    • (2001) NMR Biomed , vol.14 , pp. 19-32
    • Bluml, S.1    Moreno, A.2    Hwang, J.H.3    Ross, B.D.4
  • 13
    • 0034744085 scopus 로고    scopus 로고
    • [1-13C]glucose MRS in chronic hepatic encephalopathy in man
    • 10.1002/mrm.1131 11378875
    • Bluml S Moreno-Torres A Ross BD [1-13C]glucose MRS in chronic hepatic encephalopathy in man Magn Reson Med 2001, 45:981-993 10.1002/mrm.1131 11378875
    • (2001) Magn Reson Med , vol.45 , pp. 981-993
    • Bluml, S.1    Moreno-Torres, A.2    Ross, B.D.3
  • 14
    • 0034951375 scopus 로고    scopus 로고
    • Alternative 1-(13)C glucose infusion protocols for clinical (13)C MRS examinations of the brain
    • 10.1002/mrm.1158 11443709
    • Moreno A Bluml S Hwang JH Ross BD Alternative 1-(13)C glucose infusion protocols for clinical (13)C MRS examinations of the brain Magn Reson Med 2001, 46:39-48 10.1002/mrm.1158 11443709
    • (2001) Magn Reson Med , vol.46 , pp. 39-48
    • Moreno, A.1    Bluml, S.2    Hwang, J.H.3    Ross, B.D.4
  • 15
    • 0035089253 scopus 로고    scopus 로고
    • Direct determination of the N-acetyl-L-aspartate synthesis rate in the human brain by (13)C MRS and [l-(13)C]glucose infusion
    • 11279290
    • Moreno A Ross BD Bluml S Direct determination of the N-acetyl-L-aspartate synthesis rate in the human brain by (13)C MRS and [l-(13)C]glucose infusion J Neurochem 2001, 77:347-350 11279290
    • (2001) J Neurochem , vol.77 , pp. 347-350
    • Moreno, A.1    Ross, B.D.2    Bluml, S.3
  • 16
    • 0025249938 scopus 로고
    • The flux from glucose to glutamate in the rat brain in vivo as determined by 1H-observed/13C-edited NMR spectroscopy
    • 1968068
    • Fitzpatrick SM Hetherington HP Behar KL Shulman RG The flux from glucose to glutamate in the rat brain in vivo as determined by 1H-observed/ 13C-edited NMR spectroscopy J Cereb Blood Flow Metab 1990, 10:170-179 1968068
    • (1990) J Cereb Blood Flow Metab , vol.10 , pp. 170-179
    • Fitzpatrick, S.M.1    Hetherington, H.P.2    Behar, K.L.3    Shulman, R.G.4
  • 17
    • 0027630704 scopus 로고
    • Cerebal metabolism of [l,2-13C2]glucose and [U- 13C4]3-hydroxybutyrate in rat brain as detected by 13C NMR spectroscopy
    • 8105858
    • Künnecke B Cerdán B and Seelig J Cerebal metabolism of [l,2-13C2]glucose and [U- 13C4]3-hydroxybutyrate in rat brain as detected by 13C NMR spectroscopy NMR Biomed 1993, 6:264-277 8105858
    • (1993) NMR Biomed , vol.6 , pp. 264-277
    • Künnecke, B.1    Cerdán, B.2    Seelig, J.3
  • 18
    • 10844241455 scopus 로고    scopus 로고
    • Metabolism of [U- 13C]Leucine in Cultured Astroglial Cells
    • 10.1007/s11064-004-6879-8 15662840
    • Bixel MG Engelmann J Willker W Hamprecht B Leibfritz D Metabolism of [U- 13C]Leucine in Cultured Astroglial Cells Neurochem Res 2004, 29:2057-2067 10.1007/s11064-004-6879-8 15662840
    • (2004) Neurochem Res , vol.29 , pp. 2057-2067
    • Bixel, M.G.1    Engelmann, J.2    Willker, W.3    Hamprecht, B.4    Leibfritz, D.5
  • 20
    • 0035854660 scopus 로고    scopus 로고
    • Acute inhibition of hepatic glucose-6-phosphatase does not affect gluconeogenesis but directs gluconeogenic flux toward glycogen in fasted rats. A pharmacological study with the chlorogenic acid derivative S4048
    • 10.1074/jbc.M101223200 11346646
    • Van Dijk TH van der Sluijs FH Wiegman CH Baller JF Gustafson LA Burger HJ Herling AW Kuipers F Meijer AJ Reijngoud DJ Acute inhibition of hepatic glucose-6-phosphatase does not affect gluconeogenesis but directs gluconeogenic flux toward glycogen in fasted rats. A pharmacological study with the chlorogenic acid derivative S4048 J Biol Chem 2001, 276:25727-25735 10.1074/jbc.M101223200 11346646
    • (2001) J Biol Chem , vol.276 , pp. 25727-25735
    • Van Dijk, T.H.1    van der Sluijs, F.H.2    Wiegman, C.H.3    Baller, J.F.4    Gustafson, L.A.5    Burger, H.J.6    Herling, A.W.7    Kuipers, F.8    Meijer, A.J.9    Reijngoud, D.J.10
  • 21
    • 0142062465 scopus 로고    scopus 로고
    • Integration of [U- 13C]glucose and 2H2O for quantification of hepatic glucose production and gluconeogenesis
    • 10.1002/nbm.826 14558117
    • Perdigoto R Rodrigues TB Furtado AL Porto A Geraldes CF Jones JG Integration of [U- 13C]glucose and 2H2O for quantification of hepatic glucose production and gluconeogenesis NMR Biomed 2003, 16:189-198 10.1002/nbm.826 14558117
    • (2003) NMR Biomed , vol.16 , pp. 189-198
    • Perdigoto, R.1    Rodrigues, T.B.2    Furtado, A.L.3    Porto, A.4    Geraldes, C.F.5    Jones, J.G.6
  • 23
    • 0011190358 scopus 로고
    • The use of glucose-14 C for the evaluation of pathway of glucose metabolism
    • 14404802
    • Katz J Wood HG The use of glucose-14 C for the evaluation of pathway of glucose metabolism J Biol Chem 1960, 235:2165-2177 14404802
    • (1960) J Biol Chem , vol.235 , pp. 2165-2177
    • Katz, J.1    Wood, H.G.2
  • 24
    • 0742305444 scopus 로고    scopus 로고
    • Basic principles of metabolic modeling of NMR 13C isotopic turnover to determine rates of brain metabolism in vivo
    • 10.1016/j.ymben.2003.10.003 14734257
    • Mason GF Rothman DL Basic principles of metabolic modeling of NMR 13C isotopic turnover to determine rates of brain metabolism in vivo Metab Eng 2004, 6:75-84 10.1016/j.ymben.2003.10.003 14734257
    • (2004) Metab Eng , vol.6 , pp. 75-84
    • Mason, G.F.1    Rothman, D.L.2
  • 25
    • 0343471424 scopus 로고    scopus 로고
    • Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices
    • 10.1002/(SICI)1097-0290(19970920)55:6<831::AID-BIT2>3.0.CO;2-H
    • Schmidt K Carlsen M Nielsen J Villadsen J Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices Biotechnol Bioeng 1997, 55:831-840 10.1002/ (SICI)1097-0290(19970920)55:6<831::AID-BIT2>3.0.CO;2-H
    • (1997) Biotechnol Bioeng , vol.55 , pp. 831-840
    • Schmidt, K.1    Carlsen, M.2    Nielsen, J.3    Villadsen, J.4
  • 26
    • 0028036096 scopus 로고
    • Modeling of isotope distributions and intracellular fluxes in metabolic networks using atom mapping matrices
    • 10.1021/bp00029a006
    • Zupke C Stephanopoulos G Modeling of isotope distributions and intracellular fluxes in metabolic networks using atom mapping matrices Biotechnol Prog 1994, 10:489-498 10.1021/bp00029a006
    • (1994) Biotechnol Prog , vol.10 , pp. 489-498
    • Zupke, C.1    Stephanopoulos, G.2
  • 27
    • 0343267841 scopus 로고    scopus 로고
    • Bidirectional Reaction Steps in Metabolic Networks: III. Explicit Solution and Analysis of Isotopomer Labeling Systems
    • 10.1002/(SICI)1097-0290(1999)66:2<69::AID-BIT1>3.0.CO;2-6 10567066
    • Wiechert W Mollney M Isermann N Wurzel M de Graaf AA Bidirectional Reaction Steps in Metabolic Networks: III. Explicit Solution and Analysis of Isotopomer Labeling Systems Biotechnol Bioeng 1999, 66:69-85 10.1002/(SICI)1097-0290(1999)66:2<69::AID-BIT1>3.0.CO;2-6 10567066
    • (1999) Biotechnol Bioeng , vol.66 , pp. 69-85
    • Wiechert, W.1    Mollney, M.2    Isermann, N.3    Wurzel, M.4    de Graaf, A.A.5
  • 28
    • 0029689236 scopus 로고    scopus 로고
    • In vivo stationary flux analysis by 13C labeling experiments
    • 8623613
    • Wiechert W de Graaf AA In vivo stationary flux analysis by 13C labeling experiments Adv Biochem Eng Biotechnol 1996, 54:109-154 8623613
    • (1996) Adv Biochem Eng Biotechnol , vol.54 , pp. 109-154
    • Wiechert, W.1    de Graaf, A.A.2
  • 29
    • 0031554635 scopus 로고    scopus 로고
    • Bidirectional Reaction Steps in Metabolic Networks: I. Modeling and Simulation of Carbon Isotope Labeling Experiments
    • 10.1002/(SICI)1097-0290(19970705)55:1<101::AID-BIT12>3.0.CO;2-P
    • Wiechert W de Graaf AA Bidirectional Reaction Steps in Metabolic Networks: I. Modeling and Simulation of Carbon Isotope Labeling Experiments Biotechnol Bioeng 1997, 55:101-117 10.1002/ (SICI)1097-0290(19970705)55:1<101::AID-BIT12>3.0.CO;2-P
    • (1997) Biotechnol Bioeng , vol.55 , pp. 101-117
    • Wiechert, W.1    de Graaf, A.A.2
  • 30
    • 0031554628 scopus 로고    scopus 로고
    • Bidirectional Reaction Steps in Metabolic Networks: II. Flux Estimation and Statistical Analysis
    • 10.1002/(SICI)1097-0290(19970705)55:1<118::AID-BIT13>3.0.CO;2-I
    • Wiechert W Siefke C de Graaf AA Marx A Bidirectional Reaction Steps in Metabolic Networks: II. Flux Estimation and Statistical Analysis Biotechnol Bioeng 1997, 55:118-135 10.1002/ (SICI)1097-0290(19970705)55:1<118::AID-BIT13>3.0.CO;2-I
    • (1997) Biotechnol Bioeng , vol.55 , pp. 118-135
    • Wiechert, W.1    Siefke, C.2    de Graaf, A.A.3    Marx, A.4
  • 32
    • 12344293559 scopus 로고    scopus 로고
    • An optimized algorithm for flux estimation from isotopomer distribution in glucose metabolites
    • 10.1093/bioinformatics/bth412 15256408
    • Selivanov VA Puigjaner J Sillero A Centelles JJ Ramos-Montoya A Lee PW Cascante M An optimized algorithm for flux estimation from isotopomer distribution in glucose metabolites Bioinformatics 2004, 20:3387-3397 10.1093/bioinformatics/bth412 15256408
    • (2004) Bioinformatics , vol.20 , pp. 3387-3397
    • Selivanov, V.A.1    Puigjaner, J.2    Sillero, A.3    Centelles, J.J.4    Ramos-Montoya, A.5    Lee, P.W.6    Cascante, M.7
  • 33
    • 24144498480 scopus 로고    scopus 로고
    • Rapid simulation and analysis of isotopomer distributions using constraints based on enzyme mechanisms: An example from HT29 cancer cells
    • 10.1093/bioinformatics/bti573 16002431
    • Selivanov VA Meshalkina LE Solovjeva ON Kuchel PW Ramos-Montoya A Kochetov GA Lee PW Cascante M Rapid simulation and analysis of isotopomer distributions using constraints based on enzyme mechanisms: an example from HT29 cancer cells Bioinformatics 2005, 21:3558-3564 10.1093/bioinformatics/bti573 16002431
    • (2005) Bioinformatics , vol.21 , pp. 3558-3564
    • Selivanov, V.A.1    Meshalkina, L.E.2    Solovjeva, O.N.3    Kuchel, P.W.4    Ramos-Montoya, A.5    Kochetov, G.A.6    Lee, P.W.7    Cascante, M.8
  • 34
    • 0034813964 scopus 로고    scopus 로고
    • Possible Pitfalls of Flux Calculations Based on 13C-Labeling
    • 10.1006/mben.2000.0174 11289791
    • van Winden W Verheijen P Heijnen S Possible Pitfalls of Flux Calculations Based on 13C-Labeling Metab Eng 2001, 3:151-62 10.1006/ mben.2000.0174 11289791
    • (2001) Metab Eng , vol.3 , pp. 151-162
    • van Winden, W.1    Verheijen, P.2    Heijnen, S.3
  • 35
    • 0028036096 scopus 로고
    • Modeling of isotope distributions and intracellular fluxes in metabolic networks using atom mapping matrices
    • 10.1021/bp00029a006
    • Zupke C Stephanopoulos G Modeling of isotope distributions and intracellular fluxes in metabolic networks using atom mapping matrices Biotechnol Prog 1994, 10:489-498 10.1021/bp00029a006
    • (1994) Biotechnol Prog , vol.10 , pp. 489-498
    • Zupke, C.1    Stephanopoulos, G.2
  • 36
    • 26244452731 scopus 로고    scopus 로고
    • Revisiting the C-label distribution of the non-oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence
    • 10.1111/j.1742-4658.2005.04907.x 16176270
    • Kleijn RJ van Winden WA van Gulik WM Heijnen JJ Revisiting the C-label distribution of the non-oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence FEBS J 2005, 272:4970-4982 10.1111/j.1742-4658.2005.04907.x 16176270
    • (2005) FEBS J , vol.272 , pp. 4970-4982
    • Kleijn, R.J.1    van Winden, W.A.2    van Gulik, W.M.3    Heijnen, J.J.4
  • 39
    • 0032578533 scopus 로고    scopus 로고
    • Interpreting functional imaging studies in terms of neurotransmitter cycling
    • 21753 9751778 10.1073/pnas.95.20.11993
    • Shulman RG Rothman DL Interpreting functional imaging studies in terms of neurotransmitter cycling Proc Natl Acad Sci USA 1998, 95:11993-11998 21753 9751778 10.1073/pnas.95.20.11993
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11993-11998
    • Shulman, R.G.1    Rothman, D.L.2
  • 40
    • 0032477607 scopus 로고    scopus 로고
    • The neuroimaging of human brain function
    • 33795 9448238 10.1073/pnas.95.3.763
    • Posner MI Raichle ME The neuroimaging of human brain function Proc Natl Acad Sci USA 1998, 95:763-764 33795 9448238 10.1073/pnas.95.3.763
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 763-764
    • Posner, M.I.1    Raichle, M.E.2
  • 41
    • 0032821136 scopus 로고    scopus 로고
    • New approaches to functional neuroenergetics
    • 10.1162/089892999563454 10507889
    • Fitzpatrick SM Rothman D New approaches to functional neuroenergetics J Cogn Neurosci 1999, 11:467-471 10.1162/089892999563454 10507889
    • (1999) J Cogn Neurosci , vol.11 , pp. 467-471
    • Fitzpatrick, S.M.1    Rothman, D.2
  • 43
    • 0034744108 scopus 로고    scopus 로고
    • 13C Isotopomer Analysis of Glucose and Alanine Metabolism Reveals Cytosolic Pyruvate Compartmentation as Part of Energy Metabolism in Astrocytes
    • 10.1002/glia.1054 11329182
    • 13C Isotopomer Analysis of Glucose and Alanine Metabolism Reveals Cytosolic Pyruvate Compartmentation as Part of Energy Metabolism in Astrocytes Glia 2001, 34:200-212 10.1002/glia.1054 11329182
    • (2001) Glia , vol.34 , pp. 200-212
    • Zwingmann, C.1    Richter-Landsberg, C.2    Leibfritz, D.3
  • 44
    • 0035577325 scopus 로고    scopus 로고
    • Intracellular compartmentation of pyruvate in primary cultures of cortical neurons as detected by (13)C NMR spectroscopy with multiple (13)C labels
    • 10.1002/jnr.10048 11746401
    • Cruz F Villalba M Garcia-Espinosa MA Ballesteros P Bogonez E Satrustegui J Cerdan S Intracellular compartmentation of pyruvate in primary cultures of cortical neurons as detected by (13)C NMR spectroscopy with multiple (13)C labels J Neurosci Res 2001, 66:771-781 10.1002/jnr.10048 11746401
    • (2001) J Neurosci Res , vol.66 , pp. 771-781
    • Cruz, F.1    Villalba, M.2    Garcia-Espinosa, M.A.3    Ballesteros, P.4    Bogonez, E.5    Satrustegui, J.6    Cerdan, S.7
  • 45
    • 2442572392 scopus 로고    scopus 로고
    • Intracellular metabolic compartmentation assessed by 13C magnetic resonance spectroscopy
    • 10.1016/j.neuint.2003.10.010 15145546
    • Sonnewald U Schousboe A Qu H Waagepetersen HS Intracellular metabolic compartmentation assessed by 13C magnetic resonance spectroscopy Neurochem Int 2004, 45:305-310 10.1016/j.neuint.2003.10.010 15145546
    • (2004) Neurochem Int , vol.45 , pp. 305-310
    • Sonnewald, U.1    Schousboe, A.2    Qu, H.3    Waagepetersen, H.S.4
  • 46
    • 0037025324 scopus 로고    scopus 로고
    • Coupling of Cell Energetics With Membrane Metabolic Sensing Integrative Signaling Through Creatine Kinase Phosphotransfer Disrupted By M-Ck Gene Knock-Out
    • 10.1074/jbc.M201777200 11967264
    • Abraham MR Selivanov VA Hodgson DM Pucar D Zingman LV Wieringa B Dzeja PP Alekseev AE Terzic A Coupling of Cell Energetics With Membrane Metabolic Sensing Integrative Signaling Through Creatine Kinase Phosphotransfer Disrupted By M-Ck Gene Knock-Out J Biol Chem 2002, 277:24427-24434 10.1074/jbc.M201777200 11967264
    • (2002) J Biol Chem , vol.277 , pp. 24427-24434
    • Abraham, M.R.1    Selivanov, V.A.2    Hodgson, D.M.3    Pucar, D.4    Zingman, L.V.5    Wieringa, B.6    Dzeja, P.P.7    Alekseev, A.E.8    Terzic, A.9
  • 47
    • 0842345396 scopus 로고    scopus 로고
    • Nucleotide-gated KATP channels integrated with creatine and adenylate kinases: Amplification, tuning and sensing of energetic signals in the compartmentalized cellular environment
    • 14977185 10.1023/B:MCBI.0000009872.35940.7d
    • Selivanov VA Alekseev AE Hodgson DM Dzeja PP Terzic A Nucleotide-gated KATP channels integrated with creatine and adenylate kinases: Amplification, tuning and sensing of energetic signals in the compartmentalized cellular environment Mol Cell Biochem 2004 256/ 257:243-256 14977185 10.1023/B:MCBI.0000009872.35940.7d
    • (2004) Mol Cell Biochem , vol.257 , Issue.256 , pp. 243-256
    • Selivanov, V.A.1    Alekseev, A.E.2    Hodgson, D.M.3    Dzeja, P.P.4    Terzic, A.5
  • 48
    • 0033895842 scopus 로고    scopus 로고
    • Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion
    • 10.1085/jgp.116.2.147 10919863
    • Rich TC Fagan KA Nakata H Schaack J Cooper DM Karpen JW Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion J Gen Physiol 2000, 116:147-161 10.1085/ jgp.116.2.147 10919863
    • (2000) J Gen Physiol , vol.116 , pp. 147-161
    • Rich, T.C.1    Fagan, K.A.2    Nakata, H.3    Schaack, J.4    Cooper, D.M.5    Karpen, J.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.