Modulation of αCaMKII signaling by rapid ERα action

Brain Research

Volumn 1222, Issue , 2008, Pages 1-17

  O'Neill, Erin E ^a   Blewett, Alexis R ^a   Loria, Paula M ^b   Greene, Geoffrey L ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b PFIZER INC   (United States)

Author keywords

Ca2+ calmodulin dependent protein kinase II; Estrogen receptor; Phosphorylation; Rapid estrogen action; Signal transduction

Indexed keywords

ALPHA CALCIUM CALMODULIN KINASE II; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; GONADORELIN; MICROTUBULE ASSOCIATED PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOTRANSFERASE; RNA; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; ENZYME INHIBITOR; NERVE PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CELL STRAIN COS7; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENZYME ACTIVITY; GENETIC TRANSFECTION; HIPPOCAMPUS; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; ANIMAL; AUTORADIOGRAPHY; CELL CULTURE; CELL FRACTIONATION; CERCOPITHECUS; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; DRUG INTERACTION; EMBRYO (ANATOMY); GENE EXPRESSION REGULATION; GENETICS; METABOLISM; METHODOLOGY; MUTATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; AUTORADIOGRAPHY; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; GENE EXPRESSION REGULATION; HIPPOCAMPUS; MICE; MUTATION; NERVE TISSUE PROTEINS; NEURONS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; TRANSFECTION;

EID: 46749112166     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.05.036     Document Type: Article

References (54)

1. Adams M., Fink S.E., Shah R.A., Janssen W.G., Hayashi S., Milner T.A., McEwen B.S., and Morrison J.H. Estrogen and aging affect the subcellular distribution of ERα in the hippocampus of female rats. J. Neurosci. 22 (2002) 3608-3614
2. Ahokas A., Kaukoranta J., Wahlbeck K., and Aito M. Estrogen deficiency in severe postpartum depression: successful treatment with sublingual physiologic 17beta-estradiol: a preliminary study. J. Clin. Psychiatry. 62 (2001) 332-336
3. Almeida O., Lautenschlager N., Vasikaram S., Leedman P., and Flicker L. Association between physiological serum concentration of estrogen and the mental health of community-dwelling postmenopausal women age 70 years and over. Am. J. Geriatr. Psychiatry 13 (2005) 142-149
4. Ba F., Pang P.K., Davidge S.T., and Benishin C.G. The neuroprotective effects of estrogen in SK-N-SH neuroblastoma cell cultures. Neurochem. Int. 44 (2004) 401-411
5. Bejar R., Yasuda R., Krugers H., Hood K., and Mayford M. Transgenic calmodulin-dependent protein kinase II activation: dose-dependent effects on synaptic plasticity, learning, and memory. J. Neurosci. 22 (2002) 5719-5726
6. Beyer C., and Raab H. Nongenomic effects of oestrogen: embryonic mouse midbrain neurones respond with a rapid release of calcium from intracellular stores. Eur. J. Neurosci. 10 (1998) 255-262
7. Blanquet P. Identification of two persistently activated neurotrophin-regulated pathways in rat hippocampus. Neuroscience 95 (1999) 705-719
8. Bryant D., Bosch M.A., Ronnekleiv O.K., and Dorsa D.M. 17-beta estradiol rapidly enhances extracellular signal-regulated kinase 2 phosphorylation in the brain. Neuroscience 133 (2005) 343-352
9. Cammarota M., Bevilaqua L.R.M., Dunkley P.R., and Rostas J.A.P. Angiotensin II promotes the phosphorylation of cyclic AMP-responsive element binding protein (CREB) at Ser133 through an ERK1/2-dependent mechanism. J. Neurochem. 79 (2001) 1122-1128
10. Clarke C., Norfleet A.M., Clarke M.S., Watson C.S., Cunningham K.A., and Thomas M.L. Perimembrane localization of the estrogen receptor alpha protein in neuronal processes of cultured hippocampal neurons. Neuroendocrinology 71 (2000) 34-42
11. Day M., Sung A., Logue S., Bowlby M., and Arias R. Beta estrogen receptor knockout (BERKO) mice present attenuated hippocampal CA1 long-term potentiation and related memory deficits in contextual fear conditioning. Behav. Brain Res. 164 (2005) 128-131
12. Dubal D., Zhu H., Yu J., Rau S.W., Shughrue P.J., Merchenthaler I., Kindy M.S., and Wise P.M. Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 1952-1957
13. Duff S. A beneficial effect of estrogen on working memory in postmenopausal women taking hormone replacement therapy. Horm.Behav. 38 (2000) 262-276
14. Estrada-Camarena E., Fernández-Guasti A., and López-Rubalcava C. Antidepressant-like effect of different estrogenic compounds in the forced swimming test. Neuropsychopharmacology 28 (2003) 830-838
15. Feng W., Ribeiro R.C., Wagner R.L., Nguyen H., Apriletti J.W., Fletterick R.J., Baxter J.D., Kushner P.J., and West B.L. Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors. Science 280 (1998) 1747-1749
16. Fugger H., Foster T.C., Gustafsson J., and Rissman E.F. Novel effects of estradiol and estrogen receptor alpha and beta on cognitive function. Brain Res. 883 (2000) 258-264
17. Gaudilliere B., Konishi Y., Iglesia N., Yao G.-I., and Bonni A. A CaMKII-NeuroD signaling pathway specifies dendritic morphogenesis. Neuron 41 (2004) 229-241
18. Gonzalez M., Cabrera-Socorro A., Perez-Garcia C., Fraser J.D., Lopez F.J., Alonso F., and Meyer G. Distribution patterns of estrogen receptor alpha and beta in the human cortex and hippocampus during development and adulthood. J. Comp. Neurol. 503 (2007) 790-802
19. 2+/calmodulin-dependent protein kinases. Annu Rev. Biochem. 61 (1992) 559-601
20. Hart S., Snyder M.A., Smejkalova T., and Woolley C.S. Estrogen mobilizes a subset of estrogen receptor-alpha-immunoreactive vesicles in inhibitory presynaptic boutons in hippocampal CA1. J. Neurosci. 27 (2007) 2102-2111
21. Heldring N., Pike A., Andersson S., Matthews J., Cheng G., Hartman J., Tujague M., Ström A., Treuter E., Warner M., and Gustafsson J.A. Estrogen receptors: how do they signal and what are their targets. Physiol. Rev. 87 (2007) 905-931
22. Hu X., Qin S., Lu Y.P., Ravid R., Swaab D.F., and Zhou J.N. Decreased ERα expression in hippocampal neurons in relation to hyperphosphorylated tau in Alzheimer patients. Acta. Neuropathol. 106 (2003) 213-220
23. 2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function. Annu. Rev. Biochem. 71 (2002) 473-510
24. Kuroki Y., Fukushima K., Kanda Y., Mizuno K., and Watanabe Y. Putative membrane-bound estrogen receptors possibly stimulate mitogen-activated protein kinase in the rat hippocampus. Eur. J. Pharmacol. 400 (2000) 205-209
25. Lee S., Campomanes C.R., Sikat P.T., Greenfield A.T., Allen P.B., and McEwen B.S. Estrogen induces phosphorylation of cyclic AMP response element binding (pCREB) in primary hippocampal cells in a time-dependent manner. Neuroscience 124 (2004) 549-560
26. Liu R., Lambe E.K., and Aghajanian G.K. Somatodendritic autoreceptor regulation of serotonergic neurons: dependence on l-tryptophan and tryptophan hydroxylase-activating kinases. Eur. J. Neurosci. 21 (2005) 945-958
27. Mannella P., and Brinton R.D. Estrogen receptor protein interaction with phosphatidylinositol 3-kinase leads to activation of phosphorylated Akt and extracellular signal-regulated kinase 1/2 in the same population of cortical neurons: a unified mechanism of estrogen action. J. Neurosci. 26 (2006) 9439-9447
28. Mayford M., Bach M.E., Huang Y.Y., Wang L., Hawkins R.D., and Kandel E.R. Control of memory formation through regulated expression of a CaMKII transgene. Science 274 (1996) 1678-1683
29. McGlade-McCulloh E., Yamamoto H., Tan S.E., Brickey D.A., and Soderling T.R. Phosphorylation and regulation of glutamate receptors by calcium/calmodulin-dependent protein kinase II. Nature 362 (1993) 640-642
30. Nethrapalli I., Singh M., Guan X., Guo Q., Lubahn D.B., Korach K.S., and Toran-Allerand C.D. Estradiol (E2) elicits SRC phosphorylation in the mouse neocortex: the initial event in E2 activation of the MAPK cascade?. Endocrinology 142 (2001) 5145-5148
31. Omkumar R., Kiely M.J., Rosenstein A.J., Min K.T., and Kennedy M.B. Identification of a phosphorylation site for calcium/calmodulin-dependent protein kinase II in the NR2B subunit of the N-methyl-d-aspartate receptor. J. Biol. Chem. 279 (1996) 31670-31678
32. Piiper A., Dikic I., Lutz M.P., Leser J., Kronenberger B., Elez R., Cramer H., Müller-Esterl W., and Zeuzem S. Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, AKT, and neurite outgrowth in PC12 cells. J. Biol. Chem. 277 (2002) 43623-43630
33. Sanchez C., Diaz-Nido J., and Avila J. Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function. Prog. Neurobiol. 61 (2000) 133-168
34. Sandstrom N., and Williams C.L. Spatial memory retention is enhanced by acute and continuous estradiol replacement. Horm. Behav. 45 (2004) 128-135
35. Sawai T., Bernier F., Fukushima T., Hashimoto T., Ogura H., and Nishizawa Y. Estrogen induces a rapid increase of calcium-calmodulin-dependent protein kinase II activity in the hippocampus. Brain Res. 950 (2002) 308-311
36. Shughrue P., Lane M.V., and Merchenthaler I. Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system. J. Comp. Neurol. 388 (1997) 507-525
37. Silva A., Stevens C.F., Tonegawa S., and Wang Y. Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice. Science 257 (1992) 201-206
38. Slooter A.J. Estrogen use and early onset Alzheimer's disease: a population-based study. J. Neurol. Neurosurg. Psychiatry 67 (1999) 779-781
39. Solum D., and Handa R.J. Localization of ERalpha in pyramidal neurons of the developing rat hippocampus. Dev. Brain. Res. 128 (2001) 165-175
40. Song J., Wang C.X., Song D.K., Wang P., Shuaib A., and Hao C. Interferon gamma induces neurite outgrowth by upregulation of p35 neuron-specific cyclin-dependent kinase 5 activator via activation of ERK1/2 pathway. J. Biol. Chem. 280 (2005) 12896-12901
41. Stefani G., Onofri F., Valtorta F., Vaccaro P., Greengard P., and Benfenati F. Kinetic analysis of the phosphorylation-dependent interactions of synapsin I with rat brain synaptic vesicles. J. Physiol. 504 (1997) 501-515
42. Sun J., Chen H.Y., and Davie J.R. Effect of estradiol on histone acetylation dynamics in human breast cancer cells. J. Biol. Chem. 276 (2001) 49435-49442
43. Szego E., Barabás K., Balog J., Szilágyi N., Korach K.S., Juhász G., and Abrahám I.M. Estrogen induces estrogen receptor alpha-dependent cAMP response element-binding protein phosphorylation via mitogen activated protein kinase pathway in basal forebrain cholinergic neurons in vivo. J. Neurosci. 26 (2006) 4104-4110
44. Tang M.X. Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease. Lancet 348 (1996) 429-432
45. Trifilieff P., Herry C., Vanhoutte P., Caboche J., Desmedt A., Riedel G., Mons N., and Micheau J. Foreground contextual fear memory consolidation requires two independent phases of hippocampal ERK/CREB activation. Learn. Mem. 13 (2006) 349-358
46. Walf A., and Frye C.A. Administration of estrogen receptor beta-specific selective estrogen receptor modulators to the hippocampus decrease anxiety and depressive behavior of ovariectomized rats. Pharmacol. Biochem. Behav. 86 (2007) 407-414
47. Wen Y., Perez E.J., Green P.S., Sarkar S.N., and Simpkins J.W. nNOS is involved in estrogen mediated neuroprotection in neuroblastoma cells. NeuroReport. 15 (2004) 1515-1518
48. Winder D., Martin K.C., Muzzio I.A., Rohrer D., Chruscinski A., Kobilka B., and Kandel E.R. ERK plays a regulatory role in induction of LTP by theta frequency stimulation and its modulation by beta-adrenergic receptors. Neuron 24 (1999) 715-726
49. Woolley C. Estrogen-mediated structural and functional synaptic plasticity in the female rat hippocampus. Horm. Behav. 34 (1998) 140-148
50. 2+ influx via L-type calcium channels activates the Src/ERK/cyclic-AMP response element binding protein signal pathway and BCL-2 expression in rat hippocampal neurons: a potential initiation mechanism for estrogen-induced neuroprotection. Neuroscience 135 (2005) 59-72
51. Wu X., and McMurray C.T. Calmodulin kinase II attenuation of gene transcription by preventing cAMP response element-binding protein (CREB) dimerization and binding of the CREB-binding protein. J. Biol. Chem. 276 (2001) 1735-1741
52. Yasuda M., and Mayford M.R. CaMKII activation in the entorhinal cortex disrupts previously encoded spatial memory. Neuron 50 (2006) 309-318
53. 2+ rise and subsequent cyclic AMP response element-binding protein activation in hippocampal neurons: a potential initiation mechanism for estrogen neurotrophism. Neuroscience 132 (2005) 299-311
54. 2+ dynamics leading to ERK phosphorylation and estrogen neuroprotection in hippocampal neurons. Brain Res. 1172 (2007) 48-59