Activated nuclear metabotropic glutamate receptor mGlu5 couples to nuclear Gq/11 proteins to generate inositol 1,4,5-trisphosphate-mediated nuclear Ca2+ release

Journal of Biological Chemistry

Volumn 283, Issue 20, 2008, Pages 14072-14083

  Kumar, Vikas ^a   Jong, Yuh Jiin I ^a   O'Malley, Karen L ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b 660 S Euclid Ave ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; BIOSENSORS; CELL MEMBRANES; CYTOLOGY; INTERNET PROTOCOLS; NEURONS; NUCLEIC ACIDS; RNA; SUGARS;

DIRECT ASSESSMENTS; DOMINANT NEGATIVES; DYNAMIC ROLES; GENETIC TECHNIQUES; HEK293 CELLS; HETEROLOGOUS CELLS; IN-SITU; INOSITOL PHOSPHATES; METABOTROPIC GLUTAMATE RECEPTORS; NUCLEAR MEMBRANES; OCTADECYL; OPTICAL-; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C; PHOSPHORYLCHOLINE; PLASMA MEMBRANES; RECEPTOR ACTIVATIONS; RYANODINE RECEPTORS; SMALL INTERFERING RNAS; STRIATAL NEURONS; TRIS PHOSPHATES;

CALCIUM;

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM ION; CELL NUCLEUS RECEPTOR; EDELFOSINE; GLUTAMATE RECEPTOR 5; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL PHOSPHATE; PHOSPHOLIPASE C BETA1; RYANODINE RECEPTOR; 1 (6 ((3 METHOXYESTRA 1,3,5(10) TRIEN 17 YL)AMINO)HEXYL) 1H PYRROLE 2,5 DIONE; 1-(6-((3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL)-1H-PYRROLE-2,5-DIONE; 2 PYRROLIDONE DERIVATIVE; CALCIUM; ENZYME INHIBITOR; ESTRANE DERIVATIVE; PHOSPHOLIPASE C;

ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL NUCLEUS; CELL ORGANELLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; BIOLOGICAL MODEL; CELL LINE; CELL NUCLEUS MEMBRANE; DOMINANT GENE; DRUG ANTAGONISM; FLUORESCENCE MICROSCOPY; GENETIC PROCEDURES; METABOLISM; METHODOLOGY;

BIOSENSING TECHNIQUES; CALCIUM; CELL LINE; CELL NUCLEUS; ENZYME INHIBITORS; ESTRENES; GENES, DOMINANT; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; NUCLEAR ENVELOPE; PYRROLIDINONES; TYPE C PHOSPHOLIPASES;

EID: 46649115754     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708551200     Document Type: Article

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