InsP3 signaling induces pulse-modulated Ca2+ signals in the nucleus of airway epithelial ciliated cells

Biophysical Journal

Volumn 88, Issue 6, 2005, Pages 3946-3953

  Quesada, Ivan ^a   Verdugo, Pedro ^a,b  

^a University of Washington   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; APAMIN; CALCIUM; FLUORESCENT DYE; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; POTASSIUM CHANNEL; CALCIUM CHANNEL;

ANIMAL CELL; APAMIN SENSITIVE POTASSIUM CHANNEL; ARTICLE; CALCIUM MOBILIZATION; CALCIUM POTASSIUM EXCHANGE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL COMPARTMENTALIZATION; CELL CULTURE; CELL GRANULE; CELL NUCLEUS; CELL NUCLEUS MEMBRANE; CILIATED EPITHELIUM; CYTOSOL; ENDOPLASMIC RETICULUM; INTRANUCLEAR COMPARTMENT; ION EXCHANGE; MAST CELL; MOLECULAR DYNAMICS; NONHUMAN; PHENOMENOLOGY; RAT; RESPIRATORY EPITHELIUM; ANIMAL; BIOLOGICAL MODEL; BIOPHYSICS; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; IN VITRO STUDY; ION TRANSPORT; METABOLISM; MOUSE; TRACHEA;

ANIMALS; BIOPHYSICS; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL NUCLEUS; EPITHELIAL CELLS; INOSITOL 1,4,5-TRISPHOSPHATE; ION TRANSPORT; MICE; MODELS, BIOLOGICAL; NUCLEAR ENVELOPE; TRACHEA;

EID: 22244490002     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.105.061390     Document Type: Article

References (45)

1. 2+ homeostasis. Nat. Cell Biol. 1:409-414.
2. Al-Mohanna, F. A., K. W. Caddy, and S. R. Bolsover. 1994. The nucleus is insulated from large cytosolic calcium ion changes. Nature. 367:745-749.
3. 2+ oscillations. EMBO J. 21:3590-3597.
4. Berridge, M. J., M. D. Bootman, and H. L. Roderick. 2003. Calcium signalling: dynamics, homeostasis and remodeling. Nat. Rev. Mol. Cell Biol. 4:517-529.
5. 2+ concentration measured with specifically targeted recombinant aequorin. EMBO J. 12:4813-4819.
6. + channel in porcine coronary artery endothelium: relevance to EDHF. Br. J. Pharmacol. 135: 1133-1143.
7. 2+ oscillations on propagation to nucleus. J. Biol. Chem. 277:50226-50229.
8. Chawla, S., G. E. Hardingham, D. R. Quinn, and H. Bading. 1998. CBP: a signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV. Science. 281:1505-1509.
9. 2+ oscillations. Science. 279:227-230.
10. Divecha, N., H. Banfic, and R. F. Irvine. 1991. The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus. EMBO J. 10:3207-3214.
11. 2+ response amplitude and duration. Nature. 386:855-858.
12. Dolmetsch, R. E., K. Xu, and R. S. Lewis. 1998. Calcium oscillations increase the efficiency and specificity of gene expression. Nature. 392: 933-936.
13. Echevarria, W., M. F. Leite, M. T. Guerra, W. R. Zipfel, and M. H. Nathanson. 2003. Regulation of calcium signals in the nucleus by a nucleoplasmic reticulum. Nat. Cell Biol. 5:440-446.
14. Finch, E. A., T. J. Turner, and S. M. Goldin. 1991. Calcium as a coagonist of inositol 1,4,5-trisphosphate-induced calcium release. Science. 252: 443-446.
15. 2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors. J. Cell Biol. 163:271-282.
16. 2+ signals that are excluded from the nuclear region in pancreatic acinar cells. Pflugers Arch. 432:1055-1061.
17. 2+ from the nuclear envelope. Cell. 80:439-444.
18. Goldbeter, A., G. Dupont, and J. Halloy. 2000. The frequency encoding of pulsatility. Novartis Found. Symp. 227:19-36.
19. Hardingham, G. E., S. Chawla, C. M. Johnson, and H. Bading. 1997. Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression. Nature. 385:260-265.
20. Hardingham, G. E., F. J. L. Arnold, and H. Bading. 2001. Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity. Nat. Neurosci. 4:261-267.
21. i oscillation frequency regulates agonist-stimulated NF-kappaB transcriptional activity. J. Biol. Chem. 274:33995-33998.
22. Humbert, J. P., N. Matter, J. C. Artault, P. Koppler, and A. N. Malviya. 1996. Inositol 1,4,5-trisphosphate receptor is located to the inner nuclear membrane vindicating regulation of nuclear calcium signaling by inositol 1,4,5-trisphosphate. Discrete distribution of inositol phosphate receptors to inner and outer nuclear membranes. J. Biol. Chem. 271:478-485.
23. Kutcher, L. W., S. R. Beauman, E. I. Gruenstein, M. A. Kaetzel, and J. R. Dedman. 2003. Nuclear CaMKII inhibits neuronal differentiation of PC12 cells without affecting MAPK or CREB activation. Am. J. Physiol. Cell Physiol. 284:C1334-C1345.
24. Leite, M. F., E. C. Thrower, W. Echevarria, P. Koulen, K. Hirata, A. M. Bennett, B. E. Ehrlich, and M. H. Nathanson. 2003. Nuclear and cytosolic calcium are regulated independently. Proc. Natl. Acad. Sci. USA. 100:2975-2980.
25. 2+ spike frequency can optimize gene expression. Nature. 392:936-941.
26. +-channels in the nuclear envelope isolated from single pancreatic acinar cells. Pflugers Arch. 430:148-150.
27. Mazzanti, M., J. O. Bustamante, and H. Oberleithner. 2001. Electrical dimension of the nuclear envelope. Physiol. Rev. 81:1-19.
28. 2+ binding effects on protein conformation and protein interactions of canine cardiac calsequestrin. J. Biol. Chem. 263:1376-1381.
29. 2+ images obtained by optical sectioning of fura-2 loaded mast cells. J. Cell Biol. 116:745-759.
30. 2+. Nature. 395:908-912.
31. 2+ concentration in isolated rat liver nuclei. Proc. Natl. Acad. Sci. USA. 86:453-457.
32. 2+ pool in liver nuclei. Proc. Natl. Acad. Sci. USA. 87:6858-6862.
33. + ionophores nigericin and valinomycin and purification of the 63 kDa antibody-binding protein. Biochem. J. 300:673-683.
34. Petersen, O. H., O. V. Gerasimenko, J. V. Gerasimenko, H. Mogami, and A. V. Tepikin. 1998. The calcium store in the nuclear envelope. Cell Calcium. 23:87-90.
35. Pusl, T., J. J. Wu, T. L. Zimmerman, L. Zhang, B. E. Ehrlich, M. W. Berchtold, J. B. Hoek, S. J. Karpen, M. H. Nathanson, and A. M. Bennett. 2002. Epidermal growth factor-mediated activation of the ETS domain transcription factor Elk-1 requires nuclear calcium. J. Biol. Chem. 277:27517-27527.
36. Quesada, I., W. C. Chin, J. Steed, P. Campos-Bedolla, and P. Verdugo. 2001. Mouse mast cell secretory granules can function as intracellular ionic oscillators. Biophys. J. 80:2133-2139.
37. + from mast cell secretory granules: implications for signal transduction. Biophys. J. 85: 963-970.
38. 2+ transients that modulate nuclear function. Proc. Natl. Acad. Sci. USA. 99:9544-9549.
39. Radominska-Pandya, A., I. D. Pokrovskaya, J. Xu, J. M. Little, A. R. Jude, R. C. Kurten, and P. J. Czernik. 2002. Nuclear UDP- glucuronosyltransferases: identification of UGT2B7 and UGT1A6 in human liver nuclear membranes. Arch. Biochem. Biophys. 399:37-48.
40. Santella, L., and E. Carafoli. 1997. Calcium signaling in the cell nucleus. FASEB J. 11:1091-1109.
41. Tabares, L., M. Mazzanti, and D. E. Clapham. 1991. Chloride channels in the nuclear membrane. J. Membr. Biol. 123:49-54.
42. 2+-calmodulin signals in nucleus and cytosol. Curr. Biol. 10:86-94.
43. 2+ oscillation. EMBO J. 22:3825-3832.
44. 2+-dependent hormonal stimulation of ciliary activity. Nature. 283:764-765.
45. 2+ homeostasis. J. Cell Biol. 121:1041-1051.