Cloning, enzyme characterization of recombinant human Eg5 and the development of a new inhibitor

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 7, 2008, Pages 1397-1402

  Yang, Lei ^a   Jiang, Cheng ^a   Liu, Fei ^a   You, Qi Dong ^a   Wu, Wu Tong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Characterization; Eg5; G2 M arrest; Inhibitor; Molecular cloning

Indexed keywords

2,7,7 TRIMETHYL 4 (3 NITROPHENYL) 5 OXO N (4 CHLOROPHENYL) 1,4,5,6,7,8 HEXAHYDROQUINOLINE 3 CARBOXAMIDE; ADENOSINE TRIPHOSPHATASE; ANTINEOPLASTIC AGENT; CK0106023; COPPER ION; CPUYL064; DIMETHYLENASTRON; FERROUS ION; GENOMIC DNA; MAGNESIUM ION; MANGANESE; MEMBRANE PHOSPHOLIPID; METAL ION; MICROTUBULE DEPENDENT MOTOR PROTEIN EG5; MONASTROL; PACLITAXEL; QUINAZOLINE DERIVATIVE; RECOMBINANT PROTEIN; ZINC ION;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DOSE TIME EFFECT RELATION; DRUG TARGETING; ENZYME ACTIVITY; ENZYME ASSAY; ESCHERICHIA COLI; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MITOSIS SPINDLE; MOLECULAR CLONING; NONHUMAN; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN PURIFICATION; TEMPERATURE SENSITIVITY;

ADENOSINE TRIPHOSPHATASES; ANILIDES; ANNEXIN A5; APOPTOSIS; CELL DEATH; CELL DIVISION; CELL LINE, TUMOR; CELL PROLIFERATION; CLONING, MOLECULAR; DIMETHYL SULFOXIDE; DNA; FLOW CYTOMETRY; G2 PHASE; HUMANS; HYDROGEN-ION CONCENTRATION; KINESIN; METALS; MITOCHONDRIAL MEMBRANES; MITOTIC SPINDLE APPARATUS; QUINOLONES; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TEMPERATURE;

EID: 46449091195     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.1397     Document Type: Article

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