Presynaptic receptor arrays for clostridial neurotoxins

Trends in Microbiology

Volumn 12, Issue 10, 2004, Pages 442-446

  Montecucco, Cesare ^a   Rossetto, Ornella ^a   Schiavo, Giampietro ^b  

^a UNIVERSITY OF PADOVA   (Italy)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BOTULINUM TOXIN; LIPID; NEUROTOXIN; OLIGOSACCHARIDE; PROTEIN SUBUNIT;

CLOSTRIDIUM; ENDOCYTOSIS; NERVE ENDING; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN STRUCTURE; RECEPTOR BINDING; REVIEW; TETANUS;

CLOSTRIDIUM; NEGIBACTERIA;

EID: 4644364793     PISSN: 0966842X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tim.2004.08.002     Document Type: Article

References (41)

1. P.F. Bonventre Absorption of botulinal toxin from the gastrointestinal tract Rev. Infect. Dis. 1 1979 663 667
2. L.L. Simpson Identification of the characteristics that underlie botulinum toxin potency: implications for designing novel drugs Biochimie 82 2000 943 953
3. R.E. Shapiro Identification of a ganglioside recognition domain of tetanus toxin using a novel ganglioside photoaffinity ligand J. Biol. Chem. 272 1997 30380 30386
4. P. Emsley The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding J. Biol. Chem. 275 2000 8889 8894
5. C. Fotinou The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin J. Biol. Chem. 276 2001 32274 32281
6. H.A. Louch Identification of a binding site for ganglioside on the receptor binding domain of tetanus toxin Biochemistry 41 2002 13644 13652
7. A. Rummel Two carbohydrate binding sites in the H(CC)-domain of tetanus neurotoxin are required for toxicity J. Mol. Biol. 326 2003 835 847
8. A. Rummel The Hcc-domain of botulinum neurotoxin A and B exhibit a singular ganglioside binding site displaying serotype specific carbohydrate interaction Mol. Microbiol. 51 2004 631 643
9. J. Herreros Tetanus toxin fragment C binds to a protein present in neuronal cell lines and motoneurons J. Neurochem. 74 2000 1941 1950
10. J. Herreros Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons Mol. Biol. Cell. 12 2001 2947 2960
11. T. Nishiki The high-affinity binding of Clostridium botulinum type B neurotoxin to synaptotagmin II associated with gangliosides GT1b/GD1a FEBS Lett. 378 1996 253 257
12. T. Nishiki Binding of botulinum type B neurotoxin to Chinese hamster ovary cells transfected with rat synaptotagmin II cDNA Neurosci. Lett. 208 1996 105 108
13. M. Dong Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells J. Cell Biol. 162 2003 1293 1303
14. A. Rummel Synaptotagmin I and II act as nerve cell receptors for botulinum neurotoxin G J. Biol. Chem. 279 2004 30865 30870
15. L. Li, and B.R. Singh Isolation of synaptotagmin as a receptor for types A and E botulinum neurotoxin and analysis of their comparative binding using a new microtiter plate assay J. Nat. Toxins 7 1998 215 226
16. T.C. Umland Structure of the receptor binding fragment HC of tetanus neurotoxin Nat. Struct. Biol. 4 1997 788 792
17. G. Lalli The journey of tetanus and botulinum neurotoxins in neurons Trends Microbiol. 11 2003 431 437
18. P. Munro High sensitivity of mouse neuronal cells to tetanus toxin requires a GPI-anchored protein Biochem. Biophys. Res. Commun. 289 2001 623 629
19. C. Montecucco How do tetanus and botulinum toxins bind to neuronal membranes? Trends Biochem. Sci. 11 1986 314 317
20. T. Yamashita The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho J. Cell Biol. 157 2002 565 570
21. T. Mutoh Ganglioside GM1 binds to the Trk protein and regulates receptor function Proc. Natl. Acad. Sci. U. S. A. 92 1995 5087 5091
22. F.G. van der Goot, and T. Harder Raft membrane domains: from a liquid-ordered membrane phase to a site of pathogen attack Semin. Immunol. 13 2001 89 97
23. M. Edidin The state of lipid rafts: from model membranes to cells Annu. Rev. Biophys. Biomol. Struct. 32 2003 257 283
24. R.G. Parton, and A.A. Richards Lipid rafts and caveolae as portals for endocytosis: new insights and common mechanisms Traffic 11 2003 724 738
25. H.C. Siebert Unique conformer selection of human growth-regulatory lectin galectin-1 for ganglioside GM1 versus bacterial toxins Biochemistry 42 2003 14762 14773
26. J.E. Keller Uptake of botulinum neurotoxin into cultured neurons Biochemistry 43 2004 526 532
27. D.B. Lacy, and R.C. Stevens Sequence homology and structural analysis of the clostridial neurotoxins J. Mol. Biol. 291 1999 1091 1104
28. S. Swaminathan, and S. Eswaramoorthy Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B Nat. Struct. Biol. 7 2000 693 699
29. N.P. Morris Interaction of fragments B and C of tetanus toxin with neural and thyroid membranes and with gangliosides J. Biol. Chem. 255 1980 6071 6076
30. R.L. Goldberg Characterization of fragment C and tetanus toxin binding to rat brain membranes Mol. Pharmacol. 20 1981 565 570
31. U. Weller Chains and fragments of tetanus toxin: separation, reassociation and pharmacological properties Eur. J. Biochem. 182 1989 649 656
32. C. Montecucco Interaction of botulinum and tetanus toxins with the lipid bilayer surface Biochem. J. 251 1988 379 383
33. G. Schiavo On the role of polysialogangliosides as tetanus toxin receptors: a study with lipid monolayers Eur. J. Biochem. 199 1991 705 711
34. J. Mellanby, and I. Green How does tetanus toxin act? Neuroscience 6 1981 281 300
35. L.L. Simpson The binding fragment from tetanus toxin antagonizes the neuromuscular blocking actions of botulinum toxin J. Pharmacol. Exp. Ther. 229 1984 182 187
36. R. Hughes, and B.C. Whaler Influence of nerve-endings activity and of drugs on the rate of paralysis of rat diaphragm preparations by Clostridium botulinum type A toxin J. Physiol. 160 1962 221 233
37. E. Habermann Tetanus toxin blocks the neuromuscular transmission in vitro like botulinum A toxin Naunyn Schmiedebergs Arch. Pharmacol. 311 1980 33 40
38. P.P. Di Fiore, and P. De Camilli Endocytosis and signalling: an inseparable partnership Cell 106 2001 1 4
39. M. Kitamura Gangliosides are the binding substances in neural cells for tetanus and botulinum toxins in mice Biochim. Biophys. Acta. 1441 1999 1 3
40. R.W.M. Bullens Complex gangliosides at the neuromuscular junction are membrane receptors for autoantibodies and botulinum neurotoxin but redundant for normal synaptic function J. Neurosci. 22 2002 6876 6884
41. G. Lalli Myosin va and microtubule-based motors are required for fast axonal retrograde transport of tetanus toxin in motor neurons J. Cell Sci. 116 2003 4639 4650