Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines

Oncogene

Volumn 23, Issue 40, 2004, Pages 6736-6742

  Ku, Ja Lok ^a   Kang, Sung Bum ^a   Shin, Young Kyoung ^a   Kang, Hio Chung ^a   Hong, Sung Hye ^a   Kim, Il Jin ^a   Shin, Joo Ho ^a   Han, Inn Oc ^b   Park, Jae Gahb ^a,b  

^a Seoul National University College of Medicine   (South Korea)

^b National Cancer Center   (South Korea)

Author keywords

Hypermethylation colorectal cancer; Promoter; RUNX3

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BISULFITE; TRANSCRIPTION FACTOR RUNX1;

ARTICLE; CHEMICAL MODIFICATION; CLINICAL ARTICLE; COLON CARCINOGENESIS; COLORECTAL CANCER; COLORECTAL CARCINOMA; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENE LOCUS; GENE MUTATION; GENETIC MARKER; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HYPERMETHYLATION; MICROSATELLITE INSTABILITY; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; REPRESSOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM; STOMACH CANCER; TRANSCRIPTION REGULATION;

BASE SEQUENCE; CELL LINE, TUMOR; CLONING, MOLECULAR; COLORECTAL NEOPLASMS; CORE BINDING FACTOR ALPHA 3 SUBUNIT; DNA METHYLATION; DNA PRIMERS; DNA, COMPLEMENTARY; DNA, NEOPLASM; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); TRANSCRIPTION FACTORS;

EID: 4644363411     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207731     Document Type: Article

References (29)

1. Bangsow C, Rubins N, Glusman G, Bernstein Y, Negreanu V, Goldenberg D, Lotem J, Ben-Asher E, Lancet D, Levanon D and Groner Y. (2001). Gene, 279, 221-232.
2. Di Vinci A, Infusini E, Nigro S, Monaco R and Giaretti W. (1998a). Cancer, 83, 415-422.
3. Di Vinci A, Infusini E, Peveri C, Sciutto A, Geido E, Risio M, Rossini FP and Giaretti W. (1998b). Int. J. Cancer, 75, 45-50.
4. Esteller M, Fraga MF, Guo M, Garcia-Foncillas J, Hedenfalk I, Godwin AK, Trojan J, Vaurs-Barriere C, Bignon YJ, Ramus S, Benitez J, Caldes T, Akiyama Y, Yuasa Y, Launonen V, Canal MJ, Rodriguez R, Capella G, Peinado MA, Borg A, Aaltonen LA, Ponder BA, Baylin SB and Herman JG. (2001). Hum. Mol. Genet., 10, 3001-3007.
5. Ezaki T, Yanagisawa A, Ohta K, Aiso S, Watanabe M, Hibi T, Kato Y, Nakajima T, Ariyama T, Inazawa J, Nakamura Y and Horii A. (1996). Br. J. Cancer, 73, 424-428.
6. Guo WH, Weng LQ, Ito K, Chen LF, Nakanishi H, Tatematsu M and Ito Y. (2002). Oncogene, 21, 8351-8355.
7. Herman JG, Graff JR, Myöhänen S, Nelkin BD and Baylin SB. (1996). Proc. Natl. Acad. Sci. USA, 93, 9821-9826.
8. Hung J, Kishimoto Y, Sugio K, Virmani A, McIntire DD, Minna JD and Gazdar AF. (1995). J. Am. Med. Assoc., 273, 558-563.
9. Ito Y and Miyazono K. (2003). Curr. Opin. Genet. Dev., 13, 43-47.
10. Ku JL, Yoon KA, Kim DY and Park JG. (1999). Eur. J. Cancer, 35, 1724-1729.
11. Ku JL, Yoon KA, Kim IJ, Kim WH, Jang JY, Suh KS, Kim SW, Park YH, Hwang JH, Yoon YB and Park JG. (2002). Br. J. Cancer, 87, 187-193.
12. Lee KS, Hong SH and Bae SC. (2002). Oncogene, 21, 7156-7163.
13. Li QL, Ito K, Sakakura C, Fukamachi H, Inoue KI, Chi XZ, Lee KY, Nomura S, Lee CW, Ban SB, Kim HM, Kim WJ, Yamamoto H, Yamashita N, Yano T, Ikeda T, Itohara S, Inazawa J, Abe T, Hagiwara A, Yamagishi H, Ooe A, Kaneda A, Sugimura T, Ushijima T, Bae SC and Ito Y. (2002). Cell, 109, 113-124.
14. Melki JR, Vincent PC, Brown RD and Clark SJ. (2000). Blood, 95, 3208-3213.
15. Nam S, Jin YH, Li QL, Lee KY, Jeong GB, Ito Y, Lee JH and Bae SC. (2002). Mol. Cell. Biol., 22, 547-554.
16. Ogunbiyi OA, Goodfellow PJ, Gagliardi G, Swanson PE, Birnbaum EH, Fleshman JW, Kodner IJ and Moley JF. (1997). Gastroenterology, 113, 761-766.
17. Oh JW, Ku JL, Yoon KA, Kwon, HJ, Kim WH, Park HS, Yeo KS, Song SY, Chung JK and Park JG. (1999). Int. J. Cancer, 81, 902-910.
18. Park JG, Oie HK, Sugarbaker PH, Henslee JG, Chen TR, Johnson BE and Gazdar AF. (1987). Cancer Res., 47, 6710-6718.
19. Paz MF, Fraga MF, Avila S, Guo M, Pollan M, Herman JG and Esteller M. (2003). Cancer Res., 63, 1114-1121.
20. Praml C, Finke LH, Herfarth C, Schlag P, Schwab M and Amler L. (1995). Oncogene, 11, 1357-1362.
21. Rini D and Calabi F. (2001). Gene, 273, 13-22.
22. Smiraglia DJ, Rush LJ, Fruhwald MC, Dai Z, Held WA, Costello JF, Lang JC, Eng C, Li B, Wright FA, Caligiuri MA and Plass C. (2001). Hum. Mol. Genet., 10, 1413-1419.
23. Song SH, Jong HS, Choi HH, Inoue H, Tanabe T, Kim NK and Bang YJ. (2001). Cancer Res., 61, 4628-4635.
24. Suh ER, Ha CS, Rankin EB, Toyota M and Traber PG. (2002). J. Biol. Chem., 277, 35759-35800.
25. Tanaka K, Yanoshita R, Konishi M, Oshimura M, Maeda Y, Mori T and Miyaki M. (1993). Oncogene, 8, 2253-2258.
26. Trojan J, Brieger A, Raedle J, Esteller M and Zeuzem S. (2000). Gut, 47, 272-276.
27. van Engeland M, Roemen GM, Brink M, Pachen MM, Weijenberg MP, de Bruine AP, Arends JW, van den Brandt PA, de Goeij AF and Herman JG. (2002). Oncogene, 21, 3792-3795.
28. Yang Q, Nakamura M, Nakamura Y, Yoshimura G, Suzuma T, Umemura T, Shimizu Y, Mori I, Sakurai T and Kakudo K. (2002). Clin. Cancer Res., 8, 2890-2893.
29. Zöchbauer-Müller S, Fong KM, Maitra A, Lam S, Geradts J, Ashfaq R, Virmani AK, Milchgrub S, Gazdar AF and Minna JD. (2001). Cancer Res., 61, 3581-3585.