Characterization of the renal tubular transport of zonampanel, a novel α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, by human organic anion transporters

Drug Metabolism and Disposition

Volumn 32, Issue 10, 2004, Pages 1096-1102

  Hashimoto, Tadashi ^a   Narikawa, Shinichi ^b   Huang, Xiu Lin ^b   Minematsu, Tsuyoshi ^a   Usui, Takashi ^a   Kamimura, Hidetaka ^a   Endou, Hitoshi ^c  

^a ASTELLAS PHARMA INC   (Japan)

^b Fuji Biomedix Co Ltd   (Japan)

^c KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOHIPPURIC ACID; 6 (1 IMIDAZOLYL) 7 NITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR ANTAGONIST; CIMETIDINE; ESTRONE SULFATE; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 2; ORGANIC ANION TRANSPORTER 3; ORGANIC ANION TRANSPORTER 4; ORGANIC CATION TRANSPORTER; ORGANIC CATION TRANSPORTER 2; PROBENECID; UNCLASSIFIED DRUG; ZONAMPANEL; [1,2,3,4 TETRAHYDRO 7 (1H IMIDAZOL 1 YL) 6 NITRO 2,3 DIOXO 1 QUINOXALINYL]ACETIC ACID;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; DRUG ELIMINATION; DRUG EXCRETION; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TRANSPORT; ENZYME SPECIFICITY; HUMAN; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANIMALIA;

EID: 4644333578     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.32.10.1096     Document Type: Article

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