The Lin12-Notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity

Journal of Biological Chemistry

Volumn 279, Issue 37, 2004, Pages 38525-38531

  Boldt, Henning B ^a   Kjaer Sorensen, Kasper ^a   Overgaard, Michael T ^a   Weyer, Kathrin ^a   Poulsen, Christine B ^a   Sottrup Jensen, Lars ^a   Conover, Cheryl A ^b   Giudice, Linda C ^c   Oxvig, Claus ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b MAYO CLINIC   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CALCIUM; ENZYMES; MUTAGENESIS; SUBSTRATES;

LIN12-NOTCH REPEAT (LNR); PLASMA PROTEINS;

PROTEINS;

CALBINDIN; CALCIUM; METALLOPROTEINASE; NOTCH RECEPTOR; PREGNANCY ASSOCIATED PLASMA PROTEIN A; SOMATOMEDIN BINDING PROTEIN 4; SOMATOMEDIN BINDING PROTEIN 5;

AMINO ACID SEQUENCE; ARTICLE; CALCIUM BINDING; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DELETION MUTANT; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIN12 NOTCH REPEAT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WILD TYPE;

AMINO ACID SEQUENCE; BLOTTING, WESTERN; CALCIUM; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPEPTIDASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 4; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5; IONS; LIGANDS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PLASMIDS; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NOTCH; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION;

EID: 4644293845     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M405222200     Document Type: Article

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