Regulation of milk lipid formation and secretion in the mouse mammary gland

Advances in Experimental Medicine and Biology

Volumn 554, Issue , 2004, Pages 263-279

  McManaman, James L ^a   Palmer, Carol A ^b   Anderson, Steven ^b   Schwertfeger, Kaylee ^b   Neville, Margaret C ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOPHILIN; BUTYROPHILIN; CYTOSOLIC LIPID DROPLET; FAT DROPLET; GLUCOSE; MILK FAT; MILK PROTEIN; PROTEIN KINASE B; UNCLASSIFIED DRUG; XANTHINE OXIDASE;

BREAST MILK; CELL DIFFERENTIATION; CHEMICAL ANALYSIS; COMPLEX FORMATION; CONFERENCE PAPER; CONFOCAL MICROSCOPY; ENZYME ACTIVITY; GLUCOSE TRANSPORT; IMMUNOFLUORESCENCE MICROSCOPY; INTRACELLULAR TRANSPORT; LACTATION; LIPOGENESIS; MAMMARY GLAND; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS;

ANIMALIA;

EID: 4644269107     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4757-4242-8_22     Document Type: Conference Paper

References (49)

1. Allen JC, Keller RP, Archer P, Neville MC. Studies in human lactation: milk composition and daily secretion rates of macronutrients in the first year of lactation. Am J Clin Nutr 1991;54:69-80.
2. Baldwin RL, Yang YT. Enzymatic and metabolic changes in the development of lactation. In: Larson BL, Smith VR, editors. Lactation. New York: Academic Press, 1974; pp 349-407.
3. Buechler C, Ritter M, Duong CQ, Orso E, Kapinsky M, Schmitz G. Adipophilin is a sensitive marker for lipid loading in human blood monocytes. Biochim Biophys Acta 2001;1532:97-104.
4. Delzenne NM, Kok N. Effects of fructans-type prebiotics on lipid metabolism. Am J Clin Nutr 2001;73:456S-458S.
5. Dils RR. Comparative aspects of milk fat synthesis. J Dairy Sci 1986;69:904-910.
6. Dils RR. Milk fat synthesis. In: Mepham TB, editor. Biochemistry of Lactation. Amsterdam: Elsevier, 1983; pp 141-157.
7. Fleet IR, Goode JA, Hamon MH, Laurie MS, Linzell JL, Peaker M. Secretory activity of goat mammary glands during pregnancy and the onset of lactation. J Physiol 1975;251:763-773.
8. Gao J, Serrero G. Adipose differentiation related protein (ADRP) expressed in transfected COS-7 cells selectively stimulates long chain fatty acid uptake. J Biol Chem 1999;274:16825-16830.
9. Gao J, Ye H, Serrero G. Stimulation of adipose differentiation related protein (ADRP) expression in adipocyte precursors by long-chain fatty acids. J Cell Physiol 2000;182:297-302.
10. Gupta RA, Brockman JA, Sarraf P, Willson TM, DuBois RN. Target genes of peroxisome proliferator-activated receptor gamma in colorectal cancer cells. J Biol Chem 2001;276:29681-29687.
11. Hachey DL, Thomas MR, Emken EA, Garza C, Brown-Booth L, Adlof RO, Klein PD. Human lactation: maternal transfer of dietary triglycerides labeled with stable isotopes. J Lipid Res 1987;28:1185-1192.
12. Hamosh M, Clary TR, Chernick SS, Scow RO. Lipoprotein lipase activity of adipose and mammary tissue and plasma triglyceride in pregnant and lactating rats. Biochim Biophys Acta 1970;210:473-482.
13. Hartmann PE. Changes in the composition yield of the mammary secretion of cows during the initiation of lactation. Journal of Endocrinology 1973;59:231-247.
14. Heid HW, Moll R, Schwetlick I, Rackwitz HR, Keenan TW. Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases. Cell Tissue Res 1998;294;309-321.
15. Hollman KH. Cytology and fine structure of the mammary gland. In: Larson BL, Smith VR, editors. Lactation. New York: Academic Press, 1974; pp 3-95.
16. Jenness R. Comparative aspects of milk proteins. J Dairy Res 1979;46:197-210.
17. Jensen RG, Hitman J, Carlson SE, Couch SC, Hamosh M, Newburg DS. Milk lipids: A. Human milk lipids. In: Jensen RG, editor. Handbook of Milk Composition. San Diego: Academic Press, 1995; pp 495-542.
18. Kang S, Davis RA. Cholesterol and hepatic lipoprotein assembly and secretion. Biochim Biophys Acta 2000;1529:223-230.
19. Kuhn NJ. Progesterone withdrawal as the lactogenic trigger in the rat. J Endocrinol 1969;44:39-54.
20. Londos C, Brasaemle DL, Gruia-Gray J, Servetnick DA, Schulte CJ, Levin DM, Kimmel AR. Perilipin: unique proteins associated with intracellular neutral lipid droplets in adipocytes and steroidogenic cells. Biochem Soc Trans 1995;23:611-615.
21. Londos C, Brasaemle DL, Schulte CJ, Segrest JP, Kimmel AR. Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells. Semin Cell Dev Biol 1999;10:51-58.
22. Lu X, Gruia-Gray J, Copeland NG, Gilbert DJ, Jenkins NA, Londos C, Kimmel AR. The murine perilipin gene: the lipid droplet-associated perilipins derive from tissue-specific, mRNA splice variants and define a gene family of ancient origin. Mamm Genome 2001;12:741-749.
23. Lund LR, Romer J, Thomasset N, Solberg H, Pyke C, Bissell MJ, Dano K, Werb Z. Two distinct phases of apoptosis in mammary gland involution: Proteinase-independent and -dependent pathways. Development 1999;122:181-193.
24. Magun R, Burgering BM, Coffer PJ, Pardasani D, Lin Y, Chabot J, Sorisky A. Expression of a constitutively activated form of protein kinase B (c-Akt) in 3T3-L1 preadipose cells causes spontaneous differentiation. Endocrinology 1996;137:3590-3593.
25. Marti A, Feng Z, Altermatt HJ, Jaggi R. Milk accumulation triggers apoptosis of mammary epithelial cells. Eur J Cell Biol 1997;73:158-165.
26. Mather IH, Keenan TW. Origin and secretion of milk lipids. J Mammary Gland Biol Neoplasia 1998;3:259-273.
27. McManaman JL, Palmer CA, Wright RM, Neville MC. Functional regulation of xanthine oxidoreductase expression and localization in the mouse mammary gland: evidence of a role in lipid secretion. J Physiol 2002;545:567-579.
28. McManaman JL, Zabaronick W, Schaack J, Orlicky D. Lipid targeting domains of adipophilin. J Lipid Res 2003;44:668-673.
29. Mensenkamp AR, Havekes LM, Romijn JA, Kuipers F. Hepatic steatosis and very low density lipoprotein secretion: the involvement of apolipoprotein E. J Hepatol 35;2001:816-822.
30. Miura S, Gan JW, Brzostowski J, Parisi MJ, Schultz CJ, Londos C, Oliver B, Kimmel AR. Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium. J Biol Chem 2002;277:32253-32257.
31. Murphy DJ, Vance J. Mechanisms of lipid-body formation. Trends Biochem Sci 1999;24:109-115.
32. Murphy DJ. The biogenesis and functions of lipid bodies in animals, plants and microorganisms. Prog Lipid Res 2001;40:325-438.
33. Neville MC, McFadden TB, Forsyth I. Hormonal regulation of mammary differentiation and milk secretion. J Mammary Gland Biol Neoplasia 2002;7:49-66.
34. Neville MC, Neifert MR, editors. Lactation: Physiology, Nutrition, and Breast-Feeding. New York: Plenum Press, 1983.
35. Nguyen D-AD, Parlow AF, Neville MC. Hormonal regulation of tight junction closure in the mouse mammary epithelium during the transition from pregnancy to lactation. J Endocrinol 2001;170:347-356.
36. Palmer CA, Lubon H, McManaman JL. Transgenic mice expressing recombinant human protein C exhibit defects in lactation and impaired mammary gland development. Transgenic Res 2003;12:283-292.
37. Patton, S., Stemberger, B. H., & Knudsen, C. M., The suppression of milk fat globule secretion by colchicine: an effect coupled to inhibition of exocytosis. Biochim Biophys Acta 1977;499:404-410.
38. Rudolph M, McManaman JL, Hunter L, Phang T, Neville MC. Initiation of lactation in the mammary gland: Temporal analysis of a complex biological switch with expression profiling and trajectory clustering. J Mammary Gland Biol Neoplasia 2003;8:287-307.
39. Schwertfeger KL, McManaman JL, Palmer CA, Neville MC, Anderson SM. Expression of constitutively activated Akt in the mammary gland leads to excess lipid synthesis during pregnancy and lactation. J Lipid Res 2003;44:1100-1112.
40. Smith SJ, Cases S, Jensen DR, Chen HC, Sande E, Tow B, Sanan DA, Raber J, Eckel RH, Farese R V Jr. Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat. Nat Genet 2000;25:87-90.
41. Souza SC, Muliro KV, Liscum L, Lien P, Yamamoto MT, Schaffer JE, Dallal GE, Wang X, Kraemer FB, Obin M, Greenberg AS. Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adenoviral reconstituted system. J Biol Chem 2002;277:8267-8272.
42. Souza SC, Yamamoto MT, Franciosa MD, Lien P, Greenberg AS. BRL 49653 blocks the lipolytic actions of tumor necrosis factor-alpha: a potential new insulin-sensitizing mechanism for thiazolidinediones. Diabetes 1998;47:691-695.
43. Steiner S, Wahl D, Mangold BL, Robison R, Raymackers J, Meheus L, Anderson NL, Cordier A. Induction of the adipose differentiation-related protein in liver of etomoxir-treated rats. Biochem Biophys Res Commun 1996;218:777-782.
44. Strange R, Li F, Saurer S, Burkhardt A, Friis RR. Apoptotic cell death and tissue remodelling during mouse mammary gland involution. Development 1992;115:49-58
45. Tauchi-Sato K, Ozeki S, Houjou T, Taguchi R, Fujimoto T. The surface of lipid droplets is a phospholipid monolayer with a unique Fatty Acid composition. J Biol Chem 2002;277:44507-44512.
46. Vorbach C, Scriven A, Capecchi MR. The housekeeping gene xanthine oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland. Genes Dev 2002;6:3223-3235.
47. Vosper H, Patel L, Graham TL, Khoudoli GA, Hill A, Macphee CH, Pinto I, Smith SA, Suckling KE, Wolf CR, Palmer CN. The peroxisome proliferator-activated receptor delta promotes lipid accumulation in human macrophages. J Biol Chem 2001;276:44258-44265.
48. Wellings SR. Ultrastructural basis of lactogenesis. In: Reynolds M, Folley SJ, editors. Lactogenesis. Philadelphia: University of Pennsylvania Press, 1969; pp 5-25.
49. Wu CC, Howell KE, Neville MC, Yates JR III, McManaman JL. Proteomics reveal a link between the endoplasmic reticulum and lipid secretory mechanisms in mammary epithelial cells. Electrophoresis 2000;21:3470-3482.