Adipophilin is a sensitive marker for lipid loading in human blood monocytes

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1532, Issue 1-2, 2001, Pages 97-104

  Buechler, Christa ^a   Ritter, Mirko ^a   Duong, Chinh Quoc ^a   Orso, Evelyn ^a   Kapinsky, Michael ^a   Schmitz, Gerd ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Adipophilin; Blood monocyte; Enzymatically modified low density lipoprotein; Free fatty acid; Proliferator activated receptor

Indexed keywords

ADIPOPHILIN; CELL PROTEIN; CHOLESTEROL; CHOLESTEROL ESTER; CIGLITAZONE; FATTY ACID; LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; UNCLASSIFIED DRUG;

ARTICLE; CELL LEVEL; CONTROLLED STUDY; FATTY ACID TRANSPORT; FOAM CELL; HUMAN; HUMAN CELL; LIPID STORAGE; MONOCYTE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION;

ADULT; BASE SEQUENCE; BLOTTING, NORTHERN; BLOTTING, WESTERN; DNA PRIMERS; FLOW CYTOMETRY; HUMANS; LIPIDS; LIPOPROTEINS, LDL; MIDDLE AGED; MONOCYTES; PEPTIDES; PROSTAGLANDIN D2; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 0035978364     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1388-1981(01)00121-4     Document Type: Article

References (24)

1. Isolation and characterization of a full-length cDNA coding for an adipose differentiation-related protein
2. Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases
3. Induced expression of adipophilin mRNA in human macrophages stimulated with oxidized low-density lipoprotein and in atherosclerotic lesions
4. Conner Memorial Lecture. Oxidative modification of LDL and atherogenesis
5. Binding site on macrophages that mediate uptake and degradation of acetylated low density lipoprotein producing massive cholesterol deposition
6. On the pathogenesis of atherosclerosis. Enzymatic transformation of human low density lipoprotein to an atherogenic moiety
7. Processes in atherogenesis: Complement activation
8. Complement and atherogenesis: The unknown connection
9. Monocyte differentiation and foam cell formation induced by hydrolase modified lipoproteins
10. Adipose differentiation related protein (ADRP) expressed in transfected COS-7 cells selectively stimulates long chain fatty acid uptake
11. Stimulation of adipose differentiation related protein (ADRP) expression in adipocyte precursors by long-chain fatty acids
12. Stimulation of adipogenesis in fibroblasts by PPARgamma 2, a lipid-activated transcription factor
13. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
14. Expression of peroxisome proliferator-activated receptors (PPARS) in human astrocytic cells: PPAR gamma agonists as inducers of apoptosis
15. PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
16. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
17. Effects of purinergic agents on human mononuclear phagocytes are differentiation dependent. Implications for atherogenesis
18. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
19. Detection of intracellular cytokines by flow cytometry
20. Mechanisms of enhanced macrophage apoE secretion by oxidized LDL
21. Increased response to cholesterol feeding in apolipoprotein C1-deficient mice
22. CD36 antisense expression in 3T3-F442A preadipocytes
23. Fat change of immunomodulation
24. PPARγ agonists inhibit production of monocyte inflammatory cytokines