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Volumn 72, Issue 10, 2004, Pages 5759-5767

Borrelia burgdorferi changes its surface antigenic expression in response to host immune responses

Author keywords

[No Author keywords available]

Indexed keywords

DECORIN BINDING PROTEIN A; LIPOPROTEIN; MEMBRANE ANTIGEN; MESSENGER RNA; OUTER SURFACE PROTEIN C; PROTEIN BBF01; PROTEIN VLSE; UNCLASSIFIED DRUG;

EID: 4644243233     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.10.5759-5767.2004     Document Type: Article
Times cited : (172)

References (55)
  • 1
    • 0032523936 scopus 로고    scopus 로고
    • A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state
    • Akins, D. R., K. W. Bourell, M. J. Caimano, M. V. Norgard, and J. D. Radolf. 1998. A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state. J. Clin. Investig. 101:2240-2250.
    • (1998) J. Clin. Investig. , vol.101 , pp. 2240-2250
    • Akins, D.R.1    Bourell, K.W.2    Caimano, M.J.3    Norgard, M.V.4    Radolf, J.D.5
  • 3
    • 0035010087 scopus 로고    scopus 로고
    • Distinct regulatory pathways control expression of Borrelia burgdorferi infection-associated OspC and Erp surface proteins
    • Babb, K., N. El-Hage, J. C. Miller, J. A. Carroll, and B. Stevenson. 2001. Distinct regulatory pathways control expression of Borrelia burgdorferi infection-associated OspC and Erp surface proteins. Infect. Immun. 69:4146-4153.
    • (2001) Infect. Immun. , vol.69 , pp. 4146-4153
    • Babb, K.1    El-Hage, N.2    Miller, J.C.3    Carroll, J.A.4    Stevenson, B.5
  • 5
    • 0038104769 scopus 로고    scopus 로고
    • Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals
    • Brooks, C. S., P. S. Hefty, S. E. Jolliff, and D. R. Akins. 2003. Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals. Infect. Immun. 71:3371-3383.
    • (2003) Infect. Immun. , vol.71 , pp. 3371-3383
    • Brooks, C.S.1    Hefty, P.S.2    Jolliff, S.E.3    Akins, D.R.4
  • 6
    • 0033543568 scopus 로고    scopus 로고
    • Adherence of Borrelia burgdorferi. Identification of critical lysine residues in DbpA required for decorin binding
    • Brown, E. L., B. P. Guo, P. O'Neal, and M. Hook. 1999. Adherence of Borrelia burgdorferi. Identification of critical lysine residues in DbpA required for decorin binding. J. Biol. Chem. 274:26272-26278.
    • (1999) J. Biol. Chem. , vol.274 , pp. 26272-26278
    • Brown, E.L.1    Guo, B.P.2    O'Neal, P.3    Hook, M.4
  • 7
    • 0032967572 scopus 로고    scopus 로고
    • Effects of environmental pH on membrane proteins in Borrelia burgdorferi
    • Carroll, J. A., C. F. Garon, and T. G. Schwan. 1999. Effects of environmental pH on membrane proteins in Borrelia burgdorferi. Infect. Immun. 67:3181-3187.
    • (1999) Infect. Immun. , vol.67 , pp. 3181-3187
    • Carroll, J.A.1    Garon, C.F.2    Schwan, T.G.3
  • 9
    • 0027305425 scopus 로고
    • Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus
    • Chen, J., M. Trounstine, F. W. Alt, F. Young, C. Kurahara, J. F. Loring, and D. Huszar. 1993. Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus. Int. Immunol. 5:647-656.
    • (1993) Int. Immunol. , vol.5 , pp. 647-656
    • Chen, J.1    Trounstine, M.2    Alt, F.W.3    Young, F.4    Kurahara, C.5    Loring, J.F.6    Huszar, D.7
  • 11
    • 0032950531 scopus 로고    scopus 로고
    • Influence of outer surface protein A antibody on Borrelia burgdorferi within feeding ticks
    • de Silva, A. M., N. S. Zeidner, Y. Zhang, M. C. Dolan, J. Piesman, and E. Fikrig. 1999. Influence of outer surface protein A antibody on Borrelia burgdorferi within feeding ticks. Infect. Immun. 67:30-35.
    • (1999) Infect. Immun. , vol.67 , pp. 30-35
    • De Silva, A.M.1    Zeidner, N.S.2    Zhang, Y.3    Dolan, M.C.4    Piesman, J.5    Fikrig, E.6
  • 13
    • 0033946033 scopus 로고    scopus 로고
    • Lyme arthritis resolution with antiserum to a 37-kilodalton Borrelia burgdorferi protein
    • Feng, S., E. Hodzic, and S. W. Barthold. 2000. Lyme arthritis resolution with antiserum to a 37-kilodalton Borrelia burgdorferi protein. Infect. Immun. 68:4169-4173.
    • (2000) Infect. Immun. , vol.68 , pp. 4169-4173
    • Feng, S.1    Hodzic, E.2    Barthold, S.W.3
  • 14
    • 0345283030 scopus 로고    scopus 로고
    • Immunogenicity of Borrelia burgdorferi arthritis-related protein
    • Feng, S., E. Hodzic, K. Freet, and S. W. Barthold. 2003. Immunogenicity of Borrelia burgdorferi arthritis-related protein. Infect. Immun. 71:7211-7214.
    • (2003) Infect. Immun. , vol.71 , pp. 7211-7214
    • Feng, S.1    Hodzic, E.2    Freet, K.3    Barthold, S.W.4
  • 17
    • 0029948977 scopus 로고    scopus 로고
    • Outer surface protein C (OspC), but not P39, is a protective immunogen against a tick-transmitted Borrelia burgdorferi challenge: Evidence for a conformational protective epitope in OspC
    • Gilmore, R. D., Jr., K. J. Kappel, M. C. Dolan, T. R. Burkot, and B. J. Johnson. 1996. Outer surface protein C (OspC), but not P39, is a protective immunogen against a tick-transmitted Borrelia burgdorferi challenge: evidence for a conformational protective epitope in OspC. Infect. Immun. 64:2234-2239.
    • (1996) Infect. Immun. , vol.64 , pp. 2234-2239
    • Gilmore Jr., R.D.1    Kappel, K.J.2    Dolan, M.C.3    Burkot, T.R.4    Johnson, B.J.5
  • 19
    • 0033910411 scopus 로고    scopus 로고
    • Spirochetal lipoproteins and pathogenesis
    • Haake, D. A. 2000. Spirochetal lipoproteins and pathogenesis. Microbiology 146:1491-1504.
    • (2000) Microbiology , vol.146 , pp. 1491-1504
    • Haake, D.A.1
  • 20
    • 0031812736 scopus 로고    scopus 로고
    • Decorin-binding protein of Borrelia burgdorferi is encoded within a two-gene operon and is protective in the murine model of Lyme borreliosis
    • Hagman, K. E., P. Lahdenne, T. G. Popova, S. F. Porcella, D. R. Akins, J. D. Radolf, and M. V. Norgard. 1998. Decorin-binding protein of Borrelia burgdorferi is encoded within a two-gene operon and is protective in the murine model of Lyme borreliosis. Infect. Immun. 66:2674-2683.
    • (1998) Infect. Immun. , vol.66 , pp. 2674-2683
    • Hagman, K.E.1    Lahdenne, P.2    Popova, T.G.3    Porcella, S.F.4    Akins, D.R.5    Radolf, J.D.6    Norgard, M.V.7
  • 21
    • 0035940482 scopus 로고    scopus 로고
    • Expression of Borrelia burgdorferi OspC and DbpA is controlled by a RpoN-RpoS regulatory pathway
    • Hubner, A., X. Yang, D. M. Nolen, T. G. Popova, F. C. Cabello, and M. V. Norgard. 2001. Expression of Borrelia burgdorferi OspC and DbpA is controlled by a RpoN-RpoS regulatory pathway. Proc. Natl. Acad. Sci. USA 98:12724-12729.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12724-12729
    • Hubner, A.1    Yang, X.2    Nolen, D.M.3    Popova, T.G.4    Cabello, F.C.5    Norgard, M.V.6
  • 22
    • 0034141729 scopus 로고    scopus 로고
    • A bactericidal monoclonal antibody elicits a change in its antigen, OspB of Borrelia burgdorferi, that can be detected by limited proteolysis
    • Katona, L. I., S. Ayalew, J. L. Coleman, and J. L. Benach. 2000. A bactericidal monoclonal antibody elicits a change in its antigen, OspB of Borrelia burgdorferi, that can be detected by limited proteolysis. J. Immunol. 164:1425-1431.
    • (2000) J. Immunol. , vol.164 , pp. 1425-1431
    • Katona, L.I.1    Ayalew, S.2    Coleman, J.L.3    Benach, J.L.4
  • 23
    • 0042766235 scopus 로고    scopus 로고
    • The absence of linear plasmid 25 or 28-1 of Borrelia burgdorferi dramatically alters the kinetics of experimental infection via distinct mechanisms
    • Labandeira-Rey, M., J. Seshu, and J. T. Skare. 2003. The absence of linear plasmid 25 or 28-1 of Borrelia burgdorferi dramatically alters the kinetics of experimental infection via distinct mechanisms. Infect. Immun. 71:4608-4613.
    • (2003) Infect. Immun. , vol.71 , pp. 4608-4613
    • Labandeira-Rey, M.1    Seshu, J.2    Skare, J.T.3
  • 24
    • 0035168567 scopus 로고    scopus 로고
    • Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1
    • Labandeira-Rey, M., and J. T. Skare. 2001. Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1. Infect. Immun. 69:446-455.
    • (2001) Infect. Immun. , vol.69 , pp. 446-455
    • Labandeira-Rey, M.1    Skare, J.T.2
  • 25
    • 0033571071 scopus 로고    scopus 로고
    • An immunodominant conserved region within the variable domain of VlsE, the variable surface antigen of Borrelia burgdorferi
    • Liang, F. T., A. L. Alvarez, Y. Gu, J. M. Nowling, R. Ramamoorthy, and M. T. Philipp. 1999. An immunodominant conserved region within the variable domain of VlsE, the variable surface antigen of Borrelia burgdorferi. J. Immunol. 163:5566-5573.
    • (1999) J. Immunol. , vol.163 , pp. 5566-5573
    • Liang, F.T.1    Alvarez, A.L.2    Gu, Y.3    Nowling, J.M.4    Ramamoorthy, R.5    Philipp, M.T.6
  • 26
    • 0035058609 scopus 로고    scopus 로고
    • C-terminal invariable domain of VlsE is immunodominant but its antigenicity is scarcely conserved among strains of Lyme disease spirochetes
    • Liang, F. T., L. C. Bowers, and M. T. Philipp. 2001. C-terminal invariable domain of VlsE is immunodominant but its antigenicity is scarcely conserved among strains of Lyme disease spirochetes. Infect. Immun. 69:3224-3231.
    • (2001) Infect. Immun. , vol.69 , pp. 3224-3231
    • Liang, F.T.1    Bowers, L.C.2    Philipp, M.T.3
  • 27
    • 0037128163 scopus 로고    scopus 로고
    • An immune evasion mechanism for spirochetal persistence in Lyme borreliosis
    • Liang, F. T., M. B. Jacobs, L. C. Bowers, and M. T. Philipp. 2002. An immune evasion mechanism for spirochetal persistence in Lyme borreliosis. J. Exp. Med. 195:415-422.
    • (2002) J. Exp. Med. , vol.195 , pp. 415-422
    • Liang, F.T.1    Jacobs, M.B.2    Bowers, L.C.3    Philipp, M.T.4
  • 28
    • 0035112227 scopus 로고    scopus 로고
    • C-terminal invariable domain of VlsE may not serve as target for protective immune response against Borrelia burgdorferi
    • Liang, F. T., M. B. Jacobs, and M. T. Philipp. 2001. C-terminal invariable domain of VlsE may not serve as target for protective immune response against Borrelia burgdorferi. Infect. Immun. 69:1337-1343.
    • (2001) Infect. Immun. , vol.69 , pp. 1337-1343
    • Liang, F.T.1    Jacobs, M.B.2    Philipp, M.T.3
  • 29
    • 0037099692 scopus 로고    scopus 로고
    • Molecular adaptation of Borrelia burgdorferi in the murine host
    • Liang, F. T., F. K. Nelson, and E. Fikrig. 2002. Molecular adaptation of Borrelia burgdorferi in the murine host. J. Exp. Med. 196:275-280.
    • (2002) J. Exp. Med. , vol.196 , pp. 275-280
    • Liang, F.T.1    Nelson, F.K.2    Fikrig, E.3
  • 30
    • 0010206079 scopus 로고    scopus 로고
    • Cryptic and exposed invariable regions of VlsE, the variable surface antigen of Borrelia burgdorferi sl
    • Liang, F. T., J. M. Nowling, and M. T. Philipp. 2000. Cryptic and exposed invariable regions of VlsE, the variable surface antigen of Borrelia burgdorferi sl. J. Bacteriol. 182:3597-3601.
    • (2000) J. Bacteriol. , vol.182 , pp. 3597-3601
    • Liang, F.T.1    Nowling, J.M.2    Philipp, M.T.3
  • 31
    • 0010185122 scopus 로고    scopus 로고
    • Analysis of antibody response to invariable regions of VlsE, the variable surface antigen of Borrelia burgdorferi
    • Liang, F. T., and M. T. Philipp. 1999. Analysis of antibody response to invariable regions of VlsE, the variable surface antigen of Borrelia burgdorferi. Infect. Immun. 67:6702-6706.
    • (1999) Infect. Immun. , vol.67 , pp. 6702-6706
    • Liang, F.T.1    Philipp, M.T.2
  • 32
    • 0029008138 scopus 로고
    • Molecular analysis of neutralizing epitopes on outer surface proteins A and B of Borrelia burgdorferi
    • Ma, J., C. Gingrich-Baker, P. M. Franchi, P. Bulger, and R. T. Coughlin. 1995. Molecular analysis of neutralizing epitopes on outer surface proteins A and B of Borrelia burgdorferi. Infect. Immun. 63:2221-2227.
    • (1995) Infect. Immun. , vol.63 , pp. 2221-2227
    • Ma, J.1    Gingrich-Baker, C.2    Franchi, P.M.3    Bulger, P.4    Coughlin, R.T.5
  • 33
    • 0027310615 scopus 로고
    • Variability of osp genes and gene products among species of Lyme disease spirochetes
    • Marconi, R. T., M. E. Konkel, and C. F. Garon. 1993. Variability of osp genes and gene products among species of Lyme disease spirochetes. Infect. Immun. 61:2611-2617.
    • (1993) Infect. Immun. , vol.61 , pp. 2611-2617
    • Marconi, R.T.1    Konkel, M.E.2    Garon, C.F.3
  • 34
    • 0032858041 scopus 로고    scopus 로고
    • An OspC-specific monoclonal antibody passively protects mice from tick-transmitted infection by Borrelia burgdorferi B31
    • Mbow, M. L., R. D. Gilmore, Jr., and R. G. Titus. 1999. An OspC-specific monoclonal antibody passively protects mice from tick-transmitted infection by Borrelia burgdorferi B31. Infect. Immun. 67:5470-5472.
    • (1999) Infect. Immun. , vol.67 , pp. 5470-5472
    • Mbow, M.L.1    Gilmore Jr., R.D.2    Titus, R.G.3
  • 35
    • 0036070663 scopus 로고    scopus 로고
    • Evidence that the variable regions of the central domain of VlsE are antigenic during infection with Lyme disease spirochetes
    • McDowell, J. V., S. Y. Sung, L. T. Hu, and R. T. Marconi. 2002. Evidence that the variable regions of the central domain of VlsE are antigenic during infection with Lyme disease spirochetes. Infect. Immun. 70:4196-4203.
    • (2002) Infect. Immun. , vol.70 , pp. 4196-4203
    • McDowell, J.V.1    Sung, S.Y.2    Hu, L.T.3    Marconi, R.T.4
  • 37
    • 0032946470 scopus 로고    scopus 로고
    • Killing of Borrelia burgdorferi by antibody elicited by OspA vaccine is inefficient in the absence of complement
    • Nowling, J. M., and M. T. Philipp. 1999. Killing of Borrelia burgdorferi by antibody elicited by OspA vaccine is inefficient in the absence of complement. Infect. Immun. 67:443-445.
    • (1999) Infect. Immun. , vol.67 , pp. 443-445
    • Nowling, J.M.1    Philipp, M.T.2
  • 38
    • 0035895241 scopus 로고    scopus 로고
    • Antigenic and genetic heterogeneity of Borrelia burgdorferi populations transmitted by ticks
    • Ohnishi, J., J. Piesman, and A. M. de Silva. 2001. Antigenic and genetic heterogeneity of Borrelia burgdorferi populations transmitted by ticks. Proc. Natl. Acad. Sci. USA 98:670-675.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 670-675
    • Ohnishi, J.1    Piesman, J.2    De Silva, A.M.3
  • 40
    • 0038687785 scopus 로고    scopus 로고
    • A plasmid-encoded nicotinamidase (PncA) is essential for infectivity of Borrelia burgdorferi in a mammalian host
    • Purser, J. E., M. B. Lawrenz, M. J. Caimano, J. K. Howell, J. D. Radolf, and S. J. Norris. 2003. A plasmid-encoded nicotinamidase (PncA) is essential for infectivity of Borrelia burgdorferi in a mammalian host. Mol. Microbiol. 48:753-764.
    • (2003) Mol. Microbiol. , vol.48 , pp. 753-764
    • Purser, J.E.1    Lawrenz, M.B.2    Caimano, M.J.3    Howell, J.K.4    Radolf, J.D.5    Norris, S.J.6
  • 41
    • 0034610332 scopus 로고    scopus 로고
    • Correlation between plasmid content and infectivity in Borrelia burgdorfeti
    • Purser, J. E., and S. J. Norris. 2000. Correlation between plasmid content and infectivity in Borrelia burgdorfeti. Proc. Natl. Acad. Sci. USA 97:13865-13870.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13865-13870
    • Purser, J.E.1    Norris, S.J.2
  • 42
    • 0035085033 scopus 로고    scopus 로고
    • Borrelia burgdorferi proteins whose expression is similarly affected by culture temperature and pH
    • Ramamoorthy, R., and D. Scholl-Meeker. 2001. Borrelia burgdorferi proteins whose expression is similarly affected by culture temperature and pH. Infect. Immun. 69:2739-2742.
    • (2001) Infect. Immun. , vol.69 , pp. 2739-2742
    • Ramamoorthy, R.1    Scholl-Meeker, D.2
  • 43
    • 0037306193 scopus 로고    scopus 로고
    • Does host complement kill Borrelia burgdorferi within ticks?
    • Rathinavelu, S., A. Broadwater, and A. M. de Silva. 2003. Does host complement kill Borrelia burgdorferi within ticks? Infect. Immun. 71:822-829.
    • (2003) Infect. Immun. , vol.71 , pp. 822-829
    • Rathinavelu, S.1    Broadwater, A.2    De Silva, A.M.3
  • 44
    • 0037022354 scopus 로고    scopus 로고
    • DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete
    • Revel, A. T., A. M. Talaat, and M. V. Norgard. 2002. DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete. Proc. Natl. Acad. Sci. USA 99:1562-1567.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 1562-1567
    • Revel, A.T.1    Talaat, A.M.2    Norgard, M.V.3
  • 45
    • 0027509237 scopus 로고
    • In vitro inhibition of Borrelia burgdorferi growth by antibodies
    • Sadziene, A., P. A. Thompson, and A. G. Harbour. 1993. In vitro inhibition of Borrelia burgdorferi growth by antibodies. J. Infect. Dis. 167:165-172.
    • (1993) J. Infect. Dis. , vol.167 , pp. 165-172
    • Sadziene, A.1    Thompson, P.A.2    Harbour, A.G.3
  • 46
    • 0028926240 scopus 로고
    • Induction of an outer surface protein on Borrelia burgdorferi during tick feeding
    • Schwan, T. G., J. Piesman, W. T. Golde, M. C. Dolan, and P. A. Rosa. 1995. Induction of an outer surface protein on Borrelia burgdorferi during tick feeding. Proc. Natl. Acad. Sci. USA 92:2909-2913.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2909-2913
    • Schwan, T.G.1    Piesman, J.2    Golde, W.T.3    Dolan, M.C.4    Rosa, P.A.5
  • 47
    • 0030218954 scopus 로고    scopus 로고
    • Immunity to Lyme disease: Protection, pathology and persistence
    • Seiler, K. P., and J. J. Weis. 1996. Immunity to Lyme disease: protection, pathology and persistence. Curr. Opin. Immunol. 8:503-509.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 503-509
    • Seiler, K.P.1    Weis, J.J.2
  • 48
    • 0035849985 scopus 로고    scopus 로고
    • Lyme disease
    • Steere, A. C. 2001. Lyme disease. N. Engl. J. Med. 345:115-125.
    • (2001) N. Engl. J. Med. , vol.345 , pp. 115-125
    • Steere, A.C.1
  • 49
    • 0028828202 scopus 로고
    • Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi
    • Stevenson, B., T. G. Schwan, and P. A. Rosa. 1995. Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi. Infect. Immun. 63:4535-4539.
    • (1995) Infect. Immun. , vol.63 , pp. 4535-4539
    • Stevenson, B.1    Schwan, T.G.2    Rosa, P.A.3
  • 53
    • 0035001039 scopus 로고    scopus 로고
    • Influence of cultivation media on genetic regulatory patterns in Borrelia burgdorferi
    • Yang, X., T. G. Popova, M. S. Goldberg, and M. V. Norgard. 2001. Influence of cultivation media on genetic regulatory patterns in Borrelia burgdorferi. Infect. Immun. 69:4159-4163.
    • (2001) Infect. Immun. , vol.69 , pp. 4159-4163
    • Yang, X.1    Popova, T.G.2    Goldberg, M.S.3    Norgard, M.V.4
  • 54
    • 0030904280 scopus 로고    scopus 로고
    • Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes
    • Zhang, J. R., J. M. Hardham, A. G. Barbour, and S. J. Norris. 1997. Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes. Cell 89:275-285.
    • (1997) Cell , vol.89 , pp. 275-285
    • Zhang, J.R.1    Hardham, J.M.2    Barbour, A.G.3    Norris, S.J.4
  • 55
    • 0031850030 scopus 로고    scopus 로고
    • Kinetics and in vivo induction of genetic variation of vlsE in Borrelia burgdorferi
    • Zhang, J. R., and S. J. Norris. 1998. Kinetics and in vivo induction of genetic variation of vlsE in Borrelia burgdorferi. Infect. Immun. 66:3689-3697.
    • (1998) Infect. Immun. , vol.66 , pp. 3689-3697
    • Zhang, J.R.1    Norris, S.J.2


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