Oxidative stress stimulates testicular orphan receptor 4 through forkhead transcription factor forkhead box O3a

Endocrinology

Volumn 149, Issue 7, 2008, Pages 3490-3499

  Li, Gonghui ^a,b   Lee, Yi Fen ^a   Liu, Su ^a   Cai, Yi ^a   Xie, Shaozhen ^a   Liu, Ning Chun ^a   Bao, Bo Ying ^a,c   Chen, Zhaodian ^b   Chang, Chawnshang ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b ZHEJIANG UNIVERSITY   (China)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; HYDROGEN PEROXIDE; NEUROPEPTIDE RECEPTOR; ORPHAN RECEPTOR 4; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR FKHRL1;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE EXPRESSION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION;

ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; CHROMONES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; HUMANS; HYDROGEN PEROXIDE; LUCIFERASES; MALE; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MORPHOLINES; OXIDANTS; OXIDATIVE STRESS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECEPTORS, STEROID; RECEPTORS, THYROID HORMONE; RNA INTERFERENCE; TESTIS;

EID: 46349086079     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-0121     Document Type: Article

References (45)

1. Beato M, Herrlich P, Schutz G 1995 Steroid hormone receptors: many actors in search of a plot. Cell 83:851-857
2. Mangelsdorf DJ, Thummel C, Beato M, Herrlich P, Schutz G, Umesono K, Blumberg B, Kastner P, Mark M, Chambon P, Evans RM 1995 The nuclear receptor superfamily: the second decade. Cell 83:835-839
3. Chang C, Da Silva SL, Ideta R, Lee Y, Yeh S, Burbach JP 1994 Human and rat TR4 orphan receptors specify a subclass of the steroid receptor superfamily. Proc Natl Acad Sci USA 91:6040-6044
4. Laudet V 1997 Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor. J Mol Endocrinol 19:207-226
5. Kim E, Xie S, Yeh SD, Lee YF, Collins LL, Hu YC, Shyr CR, Mu XM, Liu NC, Chen YT, Wang PH, Chang C 2003 Disruption of TR4 orphan nuclear receptor reduces the expression of liver apolipoprotein E/C-I/C-II gene cluster. J Biol Chem 278:46919-46926
6. Lee YF, Lee HJ, Chang C 2002 Recent advances in the TR2 and TR4 orphan receptors of the nuclear receptor superfamily. J Steroid Biochem Mol Biol 81:291-308
7. Lee YF, Pan HJ, Burbach JP, Morkin E, Chang C 1997 Identification of direct repeat 4 as a positive regulatory element for the human TR4 orphan receptor. A modulator for the thyroid hormone target genes. J Biol Chem 272:12215-12220
8. Lee YF, Shyr CR, Thin TH, Lin WJ, Chang C 1999 Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: a unique signaling pathway in the steroid receptor superfamily. Proc Natl Acad Sci USA 96:14724-14729
9. Lee YF, Young WJ, Burbach JP, Chang C 1998 Negative feedback control of the retinoid-retinoic acid/retinoid X receptor pathway by the human TR4 orphan receptor, a member of the steroid receptor superfamily. J Biol Chem 273:13437-13443
10. Lee YF, Young WJ, Lin WJ, Shyr CR, Chang C 1999 Differential regulation of direct repeat 3 vitamin D3 and direct repeat 4 thyroid hormone signaling pathways by the human TR4 orphan receptor. J Biol Chem 274:16198-16205
11. Kim E, Yang Z, Liu NC, Chang C 2005 Induction of apolipoprotein E expression by TR4 orphan nuclear receptor via 5′ proximal promoter region. Biochem Biophys Res Commun 328:85-90
12. Mu X, Lee YF, Liu NC, Chen YT, Kim E, Shyr CR, Chang C 2004 Targeted inactivation of testicular nuclear orphan receptor 4 delays and disrupts late meiotic prophase and subsequent meiotic divisions of spermatogenesis. Mol Cell Biol 24:5887-5899
13. Collins LL, Lee YF, Heinlein CA, Liu NC, Chen YT, Shyr CR, Meshul CK, Uno H, Platt KA, Chang C 2004 Growth retardation and abnormal maternal behavior in mice lacking testicular orphan nuclear receptor 4. Proc Natl Acad Sci USA 101:15058-15063
14. Chen YT, Collins LL, Uno H, Chang C 2005 Deficits in motor coordination with aberrant cerebellar development in mice lacking testicular orphan nuclear receptor 4. Mol Cell Biol 25:2722-2732
15. Huq MM, Gupta P, Tsai NP, Wei LN 2006 Modulation of testicular receptor 4 (TR4) activity by MAP-kinase mediated phosphorylation. Mol Cell Proteomics 5:2072-2082
16. Lee RY, Hench J, Ruvkun G 2001 Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway. Curr Biol 11:1950-1957
17. Murakami S, Tedesco PM, Cypser JR, Johnson TE 2000 Molecular genetic mechanisms of life span manipulation in Caenorhabditis elegans. Ann NY Acad Sci 908:40-49
18. Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R 1993AC. elegans mutant that lives twice as long as wild type. Nature 366:461-464
19. Lin K, Dorman JB, Rodan A, Kenyon C 1997 daf-16: an HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278:1319-1322
20. Accili D, Arden KC 2004 FOXOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell 117:421-426
21. Greer EL, Brunet A 2005 FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 24:7410-7425
22. Burgering BM, Kops GJ 2002 Cell cycle and death control: long live Forkheads. Trends Biochem Sci 27:352-360
23. Kops GJ, Dansen TB, Polderman PE, Saarloos I, Wirtz KW, Coffer PJ, Huang TT, Bos JL, Medema RH, Burgering BM 2002 Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 419:316 -321
24. Kops GJ, Medema RH, Glassford J, Essers MA, Dijkers PF, Coffer PJ, Lam EW, Burgering BM 2002 Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. Mol Cell Biol 22:2025-2036
25. Schmidt M, Fernandez de Mattos S, van der Horst A, Klompmaker R, Kops GJ, Lam EW, Burgering BM, Medema RH 2002 Cell cycle inhibition by FOXO forkhead transcription factors involves downregulation of cyclin D. Mol Cell Biol 22:7842-7852
26. Stahl M, Dijkers PF, Kops GJ, Lens SM, Coffer PJ, Burgering BM, Medema RH 2002 The forkhead transcription factor FOXO regulates transcription of p27Kip1 and Bim in response to IL-2. J Immunol 168:5024-5031
27. Furukawa-Hibi Y, Yoshida-Araki K, Ohta T, Ikeda K, Motoyama N 2002 FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress. J Biol Chem 277:26729-26732
28. Tran H, Brunet A, Grenier JM, Datta SR, Fornace Jr AJ, DiStefano PS, Chiang LW, Greenberg ME 2002 DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 296:530-534
29. Ramaswamy S, Nakamura N, Sansal I, Bergeron L, Sellers WR 2002 A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR. Cancer Cell 2:81-91
30. Nemoto S, Finkel T 2002 Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. Science 295:2450-2452
31. Brunet A, Kanai F, Stehn J, Xu J, Sarbassova D, Frangioni JV, Dalal SN, DeCaprio JA, Greenberg ME, Yaffe MB 2002 14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport. J Cell Biol 156:817-828
32. Furuyama T, Nakazawa T, Nakano I, Mori N 2000 Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues. Biochem J 349:629-634
33. Yang L, Xie S, Jamaluddin MS, Altuwaijri S, Ni J, Kim E, Chen YT, Hu YC, Wang L, Chuang KH, Wu CT, Chang C 2005 Induction of androgen receptor expression by phosphatidylinositol 3-kinase/Akt downstream substrate, FOXO3a, and their roles in apoptosis of LNCaP prostate cancer cells. J Biol Chem 280:33558-33565
34. Biggs 3rd WH, Cavenee WK, Arden KC 2001 Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse. Mamm Genome 12:416-425
35. Xuan Z, Zhang MQ 2005 From worm to human: bioinformatics approaches to identify FOXO target genes. Mech Ageing Dev 126:209-215
36. Birkenkamp KU, Coffer PJ 2003 Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors. Biochem Soc Trans 31:292-297
37. Kirkwood TB, Austad SN 2000 Why do we age? Nature 408:233-238
38. Finkel T, Holbrook NJ 2000 Oxidants, oxidative stress and the biology of ageing. Nature 408:239-247
39. Hekimi S, Guarente L 2003 Genetics and the specificity of the aging process. Science 299:1351-1354
40. Melov S, Coskun PE, Wallace DC 1999 Mouse models of mitochondrial disease, oxidative stress, and senescence. Mutat Res 434:233-242
41. Landis GN, Tower J 2005 Superoxide dismutase evolution and life span regulation. Mech Ageing Dev 126:365-379
42. Droge W 2002 Free radicals in the physiological control of cell function. Physiol Rev 82:47-95
43. Sohal RS, Weindruch R 1996 Oxidative stress, caloric restriction, and aging. Science 273:59-63
44. Schwarze SR, Weindruch R, Aiken JM 1998 Oxidative stress and aging reduce COX I RNA and cytochrome oxidase activity in Drosophila. Free Radic Biol Med 25:740-747
45. Orr WC, Sohal RS 1994 Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263:1128-1130