A high-throughput screen for endothelial lipase using HDL as substrate

Journal of Biomolecular Screening

Volumn 13, Issue 6, 2008, Pages 468-475

  Keller, Paul M ^a   Rust, Timothy ^a   Murphy, Dennis J ^a   Matico, Rosalie ^b   Trill, John J ^b   Krawiec, John A ^a   Jurewicz, Anthony ^a   Jaye, Michael ^a   Harpel, Mark ^a   Thrall, Sara ^b   Schwartz, Benjamin ^a,b  

^a GLAXOSMITHKLINE   (United States)

^b Departments of Biological Reagents and Assay Development   (United States)

Author keywords

Alkylation protection; Coupled enzyme assay; Endothelial lipase; HDL; Interfacial enzymes

Indexed keywords

ACYL COENZYME A OXIDASE; ENDOTHELIAL LIPASE; FATTY ACID; HIGH DENSITY LIPOPROTEIN; HORSERADISH PEROXIDASE; LONG CHAIN FATTY ACID COENZYME A LIGASE; TRIACYLGLYCEROL LIPASE;

ALKYLATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME INHIBITION; ENZYME SUBSTRATE; HIGH THROUGHPUT SCREENING; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL;

ACYL-COA OXIDASE; ADENOSINE TRIPHOSPHATE; ANIMALS; BIOLOGICAL ASSAY; CHO CELLS; COENZYME A LIGASES; CRICETINAE; CRICETULUS; FATTY ACIDS, NONESTERIFIED; HORSERADISH PEROXIDASE; HUMANS; HYDROLYSIS; KINETICS; LIPASE; LIPOPROTEINS, HDL; MODELS, BIOLOGICAL; OXAZINES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

ANIMALIA; ARMORACIA RUSTICANA;

EID: 46149105665     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057108319738     Document Type: Article

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