Three-dimensional structure of rat-liver acyl-CoA oxidase in complex with a fatty acid: Insights into substrate-recognition and reactivity toward molecular oxygen

Journal of Biochemistry

Volumn 139, Issue 4, 2006, Pages 789-795

  Tokuoka, Keiji ^a   Nakajima, Yoshitaka ^a,d   Hirotsu, Ken ^a   Miyahara, Ikuko ^a   Nishina, Yasuzo ^b   Shiga, Kiyoshi ^b   Tamaoki, Haruhiko ^b   Setoyama, Chiaki ^b   Tojo, Hiromasa ^c   Miura, Retsu ^b  

^a Osaka Prefecture University   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d NAGASAKI UNIVERSITY   (Japan)

Author keywords

Acyl CoA oxidase; Complex with a fatty acid; Reactivity with oxygen; Substrate recognition; Three dimensional structure

Indexed keywords

ACYL COENZYME A OXIDASE; COENZYME A; FATTY ACID; FLAVINE ADENINE NUCLEOTIDE; LIGAND; OXYGEN; THIOESTER;

ARTICLE; BINDING SITE; CARBOXYLATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CRYSTALLIZATION; DIMERIZATION; ENZYME MECHANISM; ENZYME SUBSTRATE; HYDROGEN BOND; HYDROLYSIS; MASS SPECTROMETRY; NONHUMAN; PROTEIN ANALYSIS; RAT;

ACYL-COA DEHYDROGENASES; ACYL-COA OXIDASE; ANIMALS; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; FATTY ACIDS; HYDROGEN BONDING; LIVER; MODELS, CHEMICAL; OXIDATION-REDUCTION; OXYGEN; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RATS; SUBSTRATE SPECIFICITY;

EID: 33745667017     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/jb/mvj088     Document Type: Article

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