Loss of analgesic effect of morphine due to coadministration of rifampin

Pain

Volumn 72, Issue 1-2, 1997, Pages 261-267

  Fromm, M F ^a   Eckhardt, K ^a   Li, S ^a   Schanzle, G ^a   Hofmann, U ^a   Mikus, G ^a   Eichelbaum, M ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cold pressor test; Enzyme induction; Morphine; Morphine 6 glucuronide; Pain; Rifampin

Indexed keywords

METHADONE; MORPHINE; MORPHINE 6 GLUCURONIDE; MORPHINE SULFATE; NARCOTIC ANALGESIC AGENT; PLACEBO; RIFAMPICIN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ADULT; ANALGESIA; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COLD PRESSOR TEST; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DEMETHYLATION; DOSE TIME EFFECT RELATION; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG GLUCURONIDATION; DRUG METABOLISM; DRUG URINE LEVEL; DRUG WITHDRAWAL; ENZYME INDUCTION; HUMAN; MALE; METHADONE TREATMENT; ORAL DRUG ADMINISTRATION; PAIN; PRIORITY JOURNAL;

EID: 0030879184     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(97)00044-4     Document Type: Article

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