Conditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neurons

Developmental Biology

Volumn 319, Issue 2, 2008, Pages 179-191

  Hendershot, Tyler J ^a   Liu, Hongbin ^a   Clouthier, David E ^b   Shepherd, Iain T ^c   Coppola, Eva ^d   Studer, Michèle ^d   Firulli, Anthony B ^e   Pittman, Douglas L ^f   Howard, Marthe J ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c EMORY UNIVERSITY   (United States)

^d TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^e RILEY HOSPITAL FOR CHILDREN   (United States)

^f University of South Carolina   (United States)

Author keywords

bHLH; Cell type specific gene regulation; Gata3; Hand2 (dHand); Neural crest; Neurogenesis; Phox2; Sympathetic ganglia; TH

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; PROTEIN HAND2; PROTEIN PHOX2A; TRANSCRIPTION FACTOR GATA 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; GATA3 GENE; GENE; GENE CONTROL; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; HAND2 GENE; KNOCKOUT MOUSE; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL CREST; NONHUMAN; NORADRENERGIC SYSTEM; PHOX2A GENE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYMPATHETIC NERVE CELL; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS;

EID: 46049095468     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2008.03.036     Document Type: Article

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