1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes decrease mitochondrial membrane potential and induce apoptosis in endometrial and other cancer cell lines

Molecular Carcinogenesis

Volumn 47, Issue 7, 2008, Pages 492-507

  Hong, Jun ^a   Samudio, Ismael ^a   Chintharlapalli, Sudhakar ^a   Safe, Stephen ^a,b  

^a UNIVERSITY OF TEXAS   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

ANT; Apoptosis; C DIM; HEC1A cells; Mitochondria

Indexed keywords

1,1 BIS(3' INDOLYL) 1 (4 PHENYL)METHANE; 1,1 BIS(3' INDOLYL) 1 (4 TERT BUTYLPHENYL)METHANE; ADENINE NUCLEOTIDE TRANSLOCASE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ATRACTYLOSIDE; CASPASE; CYSTEINE; CYTOCHROME C; ENDONUCLEASE G; EOSIN; EOSIN 5 MALEIMIDE; MALEIMIDE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; TOLUENE DERIVATIVE; 1,1 BIS(3' INDOLYL) 1 (4 T BUTYLPHENYL)METHANE; 1,1-BIS(3'-INDOLYL)-1-(4-T-BUTYLPHENYL)METHANE; INDOLE DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; ENDOMETRIUM CANCER; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; GROWTH INHIBITION; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN INTERACTION; ALKYLATION; CELL CULTURE; CELL PROLIFERATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; ENDOMETRIUM TUMOR; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; NORTHERN BLOTTING; PANCREAS TUMOR; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ATRA;

ADENINE NUCLEOTIDE TRANSLOCATOR 1; ADENOSINE TRIPHOSPHATE; ALKYLATION; APOPTOSIS; ATRACTYLOSIDE; BLOTTING, NORTHERN; BLOTTING, WESTERN; CASPASES; CELL PROLIFERATION; CYTOCHROMES C; ENDOMETRIAL NEOPLASMS; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INDOLES; MEMBRANE POTENTIAL, MITOCHONDRIAL; PANCREATIC NEOPLASMS; PPAR GAMMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED;

EID: 45949105104     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20407     Document Type: Article

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