-
1
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr JF, Wyllie AH and Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26: 239-257, 1972.
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
3
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462, 1995.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
4
-
-
0018830636
-
Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
-
Wyllie AH: Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555-556, 1980.
-
(1980)
Nature
, vol.284
, pp. 555-556
-
-
Wyllie, A.H.1
-
5
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO: The biochemistry of apoptosis. Nature 407: 770-776, 2000.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
6
-
-
0030702084
-
Caspases: Intracellular signaling by proteolysis
-
Salvesen GS and Dixit VM: Caspases: intracellular signaling by proteolysis. Cell 91: 443-446, 1997.
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
7
-
-
2642689658
-
Proteases to die for
-
Cryns V and Yuan J: Proteases to die for. Genes Dev 12: 1551-1570, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 1551-1570
-
-
Cryns, V.1
Yuan, J.2
-
8
-
-
0842281645
-
Cell death: Critical control points
-
Danial NN and Korsmeyer SJ: Cell death: critical control points. Cell 116: 205-219, 2004.
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
10
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross A, McDonnell JM and Korsmeyer SJ: BCL-2 family members and the mitochondria in apoptosis. Genes Dev 13: 1899-1911, 1999.
-
(1999)
Genes Dev
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
12
-
-
19944432123
-
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
-
Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM and Huang DC: Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol Cell 17: 393-403, 2005.
-
(2005)
Mol Cell
, vol.17
, pp. 393-403
-
-
Chen, L.1
Willis, S.N.2
Wei, A.3
Smith, B.J.4
Fletcher, J.I.5
Hinds, M.G.6
Colman, P.M.7
Day, C.L.8
Adams, J.M.9
Huang, D.C.10
-
13
-
-
33751513394
-
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies
-
Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ and Cheng EH: Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies. Nat Cell Biol 8: 1348-1358, 2006.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1348-1358
-
-
Kim, H.1
Rafiuddin-Shah, M.2
Tu, H.C.3
Jeffers, J.R.4
Zambetti, G.P.5
Hsieh, J.J.6
Cheng, E.H.7
-
14
-
-
33750834023
-
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
-
van Delft MF, Wei AH, Mason KD Vandenberg CJ, Chen L, Czabotar PE, Willis SN, Scott CL, Day CL, Cory S, Adams JM, Roberts AW and Huang DC: The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. Cancer Cell 10: 389-399, 2006.
-
(2006)
Cancer Cell
, vol.10
, pp. 389-399
-
-
van Delft, M.F.1
Wei, A.H.2
Mason, K.D.3
Vandenberg, C.J.4
Chen, L.5
Czabotar, P.E.6
Willis, S.N.7
Scott, C.L.8
Day, C.L.9
Cory, S.10
Adams, J.M.11
Roberts, A.W.12
Huang, D.C.13
-
15
-
-
34547098188
-
Structural insights into the degradation of Mcl-1 induced by BH3 domains
-
Czabotar PE, Lee EF, van Delft MF, Day CL, Smith BJ, Huang DC, Fairlie WD, Hinds MG and Colman PM: Structural insights into the degradation of Mcl-1 induced by BH3 domains. Proc Natl Acad Sci USA 104: 6217-6222, 2007.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 6217-6222
-
-
Czabotar, P.E.1
Lee, E.F.2
van Delft, M.F.3
Day, C.L.4
Smith, B.J.5
Huang, D.C.6
Fairlie, W.D.7
Hinds, M.G.8
Colman, P.M.9
-
16
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T and Tanaka N: Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288: 1053-1058, 2000.
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
17
-
-
0346655211
-
BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha
-
Kim JY, Ann HJ, Ryu JH, Suk K and Park JH: BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha. J Exp Med 199: 113-124, 2004.
-
(2004)
J Exp Med
, vol.199
, pp. 113-124
-
-
Kim, J.Y.1
Ann, H.J.2
Ryu, J.H.3
Suk, K.4
Park, J.H.5
-
18
-
-
0242410719
-
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
-
Villunger A, Michalak EM, Coultas L, Mullauer F, Böck G, Ausserlechner MJ, Adams JM and Strasser A: p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 302: 1036-1038, 2003.
-
(2003)
Science
, vol.302
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
Mullauer, F.4
Böck, G.5
Ausserlechner, M.J.6
Adams, J.M.7
Strasser, A.8
-
19
-
-
33846997899
-
Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa
-
Naik E, Michalak EM, Villunger A, Adams JM and Strasser A: Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa. J Cell Biol 176: 415-424, 2007.
-
(2007)
J Cell Biol
, vol.176
, pp. 415-424
-
-
Naik, E.1
Michalak, E.M.2
Villunger, A.3
Adams, J.M.4
Strasser, A.5
-
20
-
-
22244454745
-
Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: Therapeutic implications
-
Fernandez Y, Verhaegen M, Miller TP, Rush JL, Steiner P, Opipari AW Jr, Lowe SW and Soengas MS: Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications. Cancer Res 65: 6294-6304, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 6294-6304
-
-
Fernandez, Y.1
Verhaegen, M.2
Miller, T.P.3
Rush, J.L.4
Steiner, P.5
Opipari Jr, A.W.6
Lowe, S.W.7
Soengas, M.S.8
-
21
-
-
30144442233
-
The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status
-
Perez-Galan P, Roue G, Villamor N, Montserrat E, Campo E and Colomer D: The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status. Blood 107: 257-264, 2006.
-
(2006)
Blood
, vol.107
, pp. 257-264
-
-
Perez-Galan, P.1
Roue, G.2
Villamor, N.3
Montserrat, E.4
Campo, E.5
Colomer, D.6
-
22
-
-
33846013251
-
Proteasome inhibitor PS-341 induces apoptosis in cisplatin-resistant squamous cell carcinoma cells by induction of Noxa
-
Fribley AM, Evenchik B, Zeng Q, Park BK, Guan JY, Zhang H, Hale TJ, Soengas MS, Kaufman RJ and Wang CY: Proteasome inhibitor PS-341 induces apoptosis in cisplatin-resistant squamous cell carcinoma cells by induction of Noxa. J Biol Chem 281: 31440-31447, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 31440-31447
-
-
Fribley, A.M.1
Evenchik, B.2
Zeng, Q.3
Park, B.K.4
Guan, J.Y.5
Zhang, H.6
Hale, T.J.7
Soengas, M.S.8
Kaufman, R.J.9
Wang, C.Y.10
-
23
-
-
34147157853
-
Bortezomib, but not cisplatin, induces mitochondria-dependent apoptosis accompanied by up-regulation of noxa in the non-small cell lung cancer cell line NCI-H460
-
Voortman J, Checinska A, Giaccone G, Rodriguez JA and Kruyt FA: Bortezomib, but not cisplatin, induces mitochondria-dependent apoptosis accompanied by up-regulation of noxa in the non-small cell lung cancer cell line NCI-H460. Mol Cancer Ther 6: 1046-1053, 2007.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1046-1053
-
-
Voortman, J.1
Checinska, A.2
Giaccone, G.3
Rodriguez, J.A.4
Kruyt, F.A.5
-
24
-
-
27744526342
-
A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells
-
Bockbrader KM, Tan M and Sun Y: A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells. Oncogene 24: 7381-7388, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 7381-7388
-
-
Bockbrader, K.M.1
Tan, M.2
Sun, Y.3
-
25
-
-
2342478955
-
Global Genechip profiling to identify genes responsive to p53-induced growth arrest and apoptosis in human lung carcinomas
-
Robinson M, Jiang P, Cui J, Li J, Wang Y, Swaroop M, Madore S, Lawrence TS and Sun Y: Global Genechip profiling to identify genes responsive to p53-induced growth arrest and apoptosis in human lung carcinomas. Cancer Biol Therapy 2: 406-415, 2003.
-
(2003)
Cancer Biol Therapy
, vol.2
, pp. 406-415
-
-
Robinson, M.1
Jiang, P.2
Cui, J.3
Li, J.4
Wang, Y.5
Swaroop, M.6
Madore, S.7
Lawrence, T.S.8
Sun, Y.9
-
26
-
-
0025012137
-
Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13-acetate- responsive gene that is highly expressed in an adult T-cell leukemia cell line
-
Hijikata M, Kato N, Sato T, Kagami Y and Shimotohno K: Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13-acetate- responsive gene that is highly expressed in an adult T-cell leukemia cell line. J Virol 64: 4632-4639, 1990.
-
(1990)
J Virol
, vol.64
, pp. 4632-4639
-
-
Hijikata, M.1
Kato, N.2
Sato, T.3
Kagami, Y.4
Shimotohno, K.5
-
27
-
-
33847328289
-
The Bcl-2 apoptotic switch in cancer development and therapy
-
Adams JM and Cory S: The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26: 1324-1337, 2007.
-
(2007)
Oncogene
, vol.26
, pp. 1324-1337
-
-
Adams, J.M.1
Cory, S.2
-
28
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
Oltersdorf T, Elmore SW, Shoemaker AR, Armstrong RC, Augeri DJ, Belli BA, Bruncko M, Deckwerth TL, Dinges J, Hajduk PJ, Joseph MK, Kitada S, Korsmeyer SJ, Kunzer AR, Letai A, Li C, Mitten MJ, Nettesheim DG, Ng S, Nimmer PM, O'Connor JM, Oleksijew A, Petros AM, Reed JC, Shen W, Tahir SK, Thompson CB, Tomaselli KJ, Wang B, Wendt MD, Zhang H, Fesik SW and Rosenberg SH: An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 435: 677-681, 2005.
-
(2005)
Nature
, vol.435
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
Armstrong, R.C.4
Augeri, D.J.5
Belli, B.A.6
Bruncko, M.7
Deckwerth, T.L.8
Dinges, J.9
Hajduk, P.J.10
Joseph, M.K.11
Kitada, S.12
Korsmeyer, S.J.13
Kunzer, A.R.14
Letai, A.15
Li, C.16
Mitten, M.J.17
Nettesheim, D.G.18
Ng, S.19
Nimmer, P.M.20
O'Connor, J.M.21
Oleksijew, A.22
Petros, A.M.23
Reed, J.C.24
Shen, W.25
Tahir, S.K.26
Thompson, C.B.27
Tomaselli, K.J.28
Wang, B.29
Wendt, M.D.30
Zhang, H.31
Fesik, S.W.32
Rosenberg, S.H.33
more..
|