메뉴 건너뛰기




Volumn 6, Issue , 2008, Pages

Immunostimulatory effects of three classes of CpG oligodeoxynucleotides on PBMC from HCV chronic carriers

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ALPHA2B INTERFERON; CPG OLIGODEOXYNUCLEOTIDE; CPG OLIGODEOXYNUCLEOTIDE A; CPG OLIGODEOXYNUCLEOTIDE B; CPG OLIGODEOXYNUCLEOTIDE C; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 10; RIBAVIRIN;

EID: 45949092349     PISSN: None     EISSN: 14768518     Source Type: Journal    
DOI: 10.1186/1476-8518-6-3     Document Type: Article
Times cited : (16)

References (63)
  • 1
    • 32344431567 scopus 로고    scopus 로고
    • Chronic hepatitis C virus management: 2000-2005 update
    • 16368925
    • Hughes CA Shafran SD Chronic hepatitis C virus management: 2000-2005 update Ann Pharmacother 2006, 40:74-82. 16368925
    • (2006) Ann Pharmacother , vol.40 , pp. 74-82
    • Hughes, C.A.1    Shafran, S.D.2
  • 2
    • 27644542713 scopus 로고    scopus 로고
    • Chronic hepatitis C: An age wave of disease burden
    • quiz S307-11
    • McHutchison JG Bacon BR Chronic hepatitis C: An age wave of disease burden Am J Manag Care 2005, 11:S286-95; quiz S307-11. 16232012
    • (2005) Am J Manag Care , vol.11
    • McHutchison, J.G.1    Bacon, B.R.2
  • 3
    • 0029949486 scopus 로고    scopus 로고
    • Genetic heterogeneity of hepatitis C virus. The clinical significance of genotypes and quasispecies behavior
    • 8792081
    • Marrone A Sallie R Genetic heterogeneity of hepatitis C virus. The clinical significance of genotypes and quasispecies behavior Clin Lab Med 1996, 16:429-449. 8792081
    • (1996) Clin Lab Med , vol.16 , pp. 429-449
    • Marrone, A.1    Sallie, R.2
  • 4
    • 33645038201 scopus 로고    scopus 로고
    • Immunopathogenesis of hepatitis C virus infection: Multifaceted strategies subverting innate and adaptive immunity
    • 10.2169/internalmedicine.45.1530 16543687
    • Kanto T Hayashi N Immunopathogenesis of hepatitis C virus infection: multifaceted strategies subverting innate and adaptive immunity Intern Med 2006, 45:183-191. 10.2169/internalmedicine.45.1530 16543687
    • (2006) Intern Med , vol.45 , pp. 183-191
    • Kanto, T.1    Hayashi, N.2
  • 5
    • 32644490562 scopus 로고    scopus 로고
    • A target on the move: Innate and adaptive immune escape strategies of hepatitis C virus
    • 10.1016/j.antiviral.2005.12.001 16413618
    • Thimme R Lohmann V Weber F A target on the move: Innate and adaptive immune escape strategies of hepatitis C virus Antiviral Res 2006, 69:129-141. 10.1016/j.antiviral.2005.12.001 16413618
    • (2006) Antiviral Res , vol.69 , pp. 129-141
    • Thimme, R.1    Lohmann, V.2    Weber, F.3
  • 6
    • 0035121503 scopus 로고    scopus 로고
    • Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection
    • 10.1053/gast.2001.21212 11159892
    • Bain C Fatmi A Zoulim F Zarski JP Trepo C Inchauspe G Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection Gastroenterology 2001, 120:512-524. 10.1053/gast.2001.21212 11159892
    • (2001) Gastroenterology , vol.120 , pp. 512-524
    • Bain, C.1    Fatmi, A.2    Zoulim, F.3    Zarski, J.P.4    Trepo, C.5    Inchauspe, G.6
  • 7
    • 0031915132 scopus 로고    scopus 로고
    • Liver-derived CTL in hepatitis C virus infection: Breadth and specificity of responses in a cohort of persons with chronic infection
    • 9570570
    • Wong DK Dudley DD Afdhal NH Dienstag J Rice CM Wang L Houghton M Walker BD Koziel MJ Liver-derived CTL in hepatitis C virus infection: Breadth and specificity of responses in a cohort of persons with chronic infection J Immunol 1998, 160:1479-1488. 9570570
    • (1998) J Immunol , vol.160 , pp. 1479-1488
    • Wong, D.K.1    Dudley, D.D.2    Afdhal, N.H.3    Dienstag, J.4    Rice, C.M.5    Wang, L.6    Houghton, M.7    Walker, B.D.8    Koziel, M.J.9
  • 9
    • 0031308730 scopus 로고    scopus 로고
    • The role of immune responses in the pathogenesis of hepatitis C virus infection
    • 10.1111/j.1365-2893.1997.tb00178.x 9429208
    • Koziel MJ The role of immune responses in the pathogenesis of hepatitis C virus infection J Viral Hepat 1997, 4(Suppl 2):31-41. 10.1111/ j.1365-2893.1997.tb00178.x 9429208
    • (1997) J Viral Hepat , vol.4 , Issue.SUPPL. 2 , pp. 31-41
    • Koziel, M.J.1
  • 10
    • 0031808407 scopus 로고    scopus 로고
    • Intrahepatic hepatitis C virus-specific cytotoxic T lymphocyte activity and response to interferon alfa therapy in chronic hepatitis C
    • 10.1002/hep.510280129 9657116
    • Nelson DR Marousis CG Ohno T Davis GL Lau JY Intrahepatic hepatitis C virus-specific cytotoxic T lymphocyte activity and response to interferon alfa therapy in chronic hepatitis C Hepatology 1998, 28:225-230. 10.1002/hep.510280129 9657116
    • (1998) Hepatology , vol.28 , pp. 225-230
    • Nelson, D.R.1    Marousis, C.G.2    Ohno, T.3    Davis, G.L.4    Lau, J.Y.5
  • 11
    • 0036788253 scopus 로고    scopus 로고
    • Peginterferon alone or with ribavirin enhances HCV-specific CD4 T-helper 1 responses in patients with chronic hepatitis C
    • 10.1053/gast.2002.36045 12360469
    • Kamal SM Fehr J Roesler B Peters T Rasenack JW Peginterferon alone or with ribavirin enhances HCV-specific CD4 T-helper 1 responses in patients with chronic hepatitis C Gastroenterology 2002, 123:1070-1083. 10.1053/gast.2002.36045 12360469
    • (2002) Gastroenterology , vol.123 , pp. 1070-1083
    • Kamal, S.M.1    Fehr, J.2    Roesler, B.3    Peters, T.4    Rasenack, J.W.5
  • 12
    • 0033960092 scopus 로고    scopus 로고
    • Hepatitis C virus-specific T-cell reactivity during interferon and ribavirin treatment in chronic hepatitis C
    • 10.1016/S0016-5085(00)70217-4 10648463
    • Cramp ME Rossol S Chokshi S Carucci P Williams R Naoumov NV Hepatitis C virus-specific T-cell reactivity during interferon and ribavirin treatment in chronic hepatitis C Gastroenterology 2000, 118:346-355. 10.1016/S0016-5085(00)70217-4 10648463
    • (2000) Gastroenterology , vol.118 , pp. 346-355
    • Cramp, M.E.1    Rossol, S.2    Chokshi, S.3    Carucci, P.4    Williams, R.5    Naoumov, N.V.6
  • 13
    • 33644520948 scopus 로고    scopus 로고
    • Therapy of hepatitis C: From empiricism to eradication
    • 10.1002/hep.21064 16447262
    • Pawlotsky JM Therapy of hepatitis C: From empiricism to eradication Hepatology 2006, 43:S207-20. 10.1002/hep.21064 16447262
    • (2006) Hepatology , vol.43
    • Pawlotsky, J.M.1
  • 14
    • 17644402442 scopus 로고    scopus 로고
    • Type I interferons (alpha/beta) in immunity and autoimmunity
    • 10.1146/annurev.immunol.23.021704.115843 15771573
    • Theofilopoulos AN Baccala R Beutler B Kono DH Type I interferons (alpha/ beta) in immunity and autoimmunity Annu Rev Immunol 2005, 23:307-336. 10.1146/annurev.immunol.23.021704.115843 15771573
    • (2005) Annu Rev Immunol , vol.23 , pp. 307-336
    • Theofilopoulos, A.N.1    Baccala, R.2    Beutler, B.3    Kono, D.H.4
  • 15
    • 33646560284 scopus 로고    scopus 로고
    • The metabolism, pharmacokinetics and mechanisms of antiviral activity of ribavirin against hepatitis C virus
    • 10.1007/s00018-005-5455-y 16501888
    • Dixit NM Perelson AS The metabolism, pharmacokinetics and mechanisms of antiviral activity of ribavirin against hepatitis C virus Cell Mol Life Sci 2006, 63:832-842. 10.1007/s00018-005-5455-y 16501888
    • (2006) Cell Mol Life Sci , vol.63 , pp. 832-842
    • Dixit, N.M.1    Perelson, A.S.2
  • 16
    • 30344455618 scopus 로고    scopus 로고
    • Treating HCV with ribavirin analogues and ribavirin-like molecules
    • 10.1093/jac/dki405 16293677
    • Gish RG Treating HCV with ribavirin analogues and ribavirin-like molecules J Antimicrob Chemother 2006, 57:8-13. 10.1093/jac/dki405 16293677
    • (2006) J Antimicrob Chemother , vol.57 , pp. 8-13
    • Gish, R.G.1
  • 17
    • 26244439300 scopus 로고    scopus 로고
    • Relationship between early HCV kinetics and T-cell reactivity in chronic hepatitis C genotype 1 during peginterferon and ribavirin therapy
    • 10.1016/j.jhep.2005.05.024 16139918
    • Tang KH Herrmann E Cooksley H Tatman N Chokshi S Williams R Zeuzem S Naoumov NV Relationship between early HCV kinetics and T-cell reactivity in chronic hepatitis C genotype 1 during peginterferon and ribavirin therapy J Hepatol 2005, 43:776-782. 10.1016/j.jhep.2005.05.024 16139918
    • (2005) J Hepatol , vol.43 , pp. 776-782
    • Tang, K.H.1    Herrmann, E.2    Cooksley, H.3    Tatman, N.4    Chokshi, S.5    Williams, R.6    Zeuzem, S.7    Naoumov, N.V.8
  • 18
    • 0036190222 scopus 로고    scopus 로고
    • Interferon-alpha-2b plus ribavirin: A review of its use in the management of chronic hepatitis C
    • 10.2165/00003495-200262030-00009 11827565
    • Scott LJ Perry CM Interferon-alpha-2b plus ribavirin: A review of its use in the management of chronic hepatitis C Drugs 2002, 62:507-556. 10.2165/00003495-200262030-00009 11827565
    • (2002) Drugs , vol.62 , pp. 507-556
    • Scott, L.J.1    Perry, C.M.2
  • 19
    • 0037806029 scopus 로고    scopus 로고
    • Effect of ribavirin on hepatitis C viral kinetics in patients treated with pegylated interferon
    • 10.1053/jhep.2003.50218 12774014
    • Herrmann E Lee JH Marinos G Modi M Zeuzem S Effect of ribavirin on hepatitis C viral kinetics in patients treated with pegylated interferon Hepatology 2003, 37:1351-1358. 10.1053/jhep.2003.50218 12774014
    • (2003) Hepatology , vol.37 , pp. 1351-1358
    • Herrmann, E.1    Lee, J.H.2    Marinos, G.3    Modi, M.4    Zeuzem, S.5
  • 20
    • 4344574012 scopus 로고    scopus 로고
    • Impact of alpha interferon and ribavirin on the function of maturing dendritic cells
    • 514729 15328100 10.1128/AAC.48.9.3382-3389.2004
    • Barnes E Salio M Cerundolo V Medlin J Murphy S Dusheiko G Klenerman P Impact of alpha interferon and ribavirin on the function of maturing dendritic cells Antimicrob Agents Chemother 2004, 48:3382-3389. 514729 15328100 10.1128/AAC.48.9.3382-3389.2004
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 3382-3389
    • Barnes, E.1    Salio, M.2    Cerundolo, V.3    Medlin, J.4    Murphy, S.5    Dusheiko, G.6    Klenerman, P.7
  • 21
    • 0010693314 scopus 로고    scopus 로고
    • Effects of the ribavirin-interferon alpha combination on cultured peripheral blood mononuclear cells from chronic hepatitis C patients
    • 10.1006/cyto.1997.0333 9722937
    • Martin J Navas S Quiroga JA Pardo M Carreno V Effects of the ribavirin-interferon alpha combination on cultured peripheral blood mononuclear cells from chronic hepatitis C patients Cytokine 1998, 10:635-644. 10.1006/cyto.1997.0333 9722937
    • (1998) Cytokine , vol.10 , pp. 635-644
    • Martin, J.1    Navas, S.2    Quiroga, J.A.3    Pardo, M.4    Carreno, V.5
  • 22
    • 0033024781 scopus 로고    scopus 로고
    • Ribavirin polarizes human T cell responses towards a Type 1 cytokine profile
    • 10.1016/S0168-8278(99)80093-2 10190717
    • Tam RC Pai B Bard J Lim C Averett DR Phan UT Milovanovic T Ribavirin polarizes human T cell responses towards a Type 1 cytokine profile J Hepatol 1999, 30:376-382. 10.1016/S0168-8278(99)80093-2 10190717
    • (1999) J Hepatol , vol.30 , pp. 376-382
    • Tam, R.C.1    Pai, B.2    Bard, J.3    Lim, C.4    Averett, D.R.5    Phan, U.T.6    Milovanovic, T.7
  • 23
    • 34247255323 scopus 로고    scopus 로고
    • Direct evidence for immunomodulatory properties of ribavirin on T-cell reactivity to hepatitis C virus
    • 10.1016/j.antiviral.2006.11.008 17210188
    • Rigopoulou EI Abbott WG Williams R Naoumov NV Direct evidence for immunomodulatory properties of ribavirin on T-cell reactivity to hepatitis C virus Antiviral Res 2007, 75:36-42. 10.1016/ j.antiviral.2006.11.008 17210188
    • (2007) Antiviral Res , vol.75 , pp. 36-42
    • Rigopoulou, E.I.1    Abbott, W.G.2    Williams, R.3    Naoumov, N.V.4
  • 24
    • 23944462641 scopus 로고    scopus 로고
    • Mechanism of action of interferon and ribavirin in treatment of hepatitis C
    • 10.1038/nature04082 16107837
    • Feld JJ Hoofnagle JH Mechanism of action of interferon and ribavirin in treatment of hepatitis C Nature 2005, 436:967-972. 10.1038/nature04082 16107837
    • (2005) Nature , vol.436 , pp. 967-972
    • Feld, J.J.1    Hoofnagle, J.H.2
  • 26
    • 33745847180 scopus 로고    scopus 로고
    • TLRs, NLRs and RLRs: A trinity of pathogen sensors that co-operate in innate immunity
    • 10.1016/j.it.2006.06.003 16807108
    • Creagh EM O'Neill LA TLRs, NLRs and RLRs: A trinity of pathogen sensors that co-operate in innate immunity Trends Immunol 2006, 27:352-357. 10.1016/j.it.2006.06.003 16807108
    • (2006) Trends Immunol , vol.27 , pp. 352-357
    • Creagh, E.M.1    O'Neill, L.A.2
  • 27
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • 10.1038/ni1112 15454922
    • Iwasaki A Medzhitov R Toll-like receptor control of the adaptive immune responses Nat Immunol 2004, 5:987-995. 10.1038/ni1112 15454922
    • (2004) Nat Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 28
    • 33745946911 scopus 로고    scopus 로고
    • Therapeutic potential of Toll-like receptor 9 activation
    • 10.1038/nrd2059 16763660
    • Krieg AM Therapeutic potential of Toll-like receptor 9 activation Nat Rev Drug Discov 2006, 5:471-484. 10.1038/nrd2059 16763660
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 471-484
    • Krieg, A.M.1
  • 29
    • 0030239828 scopus 로고    scopus 로고
    • Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA
    • 8757300
    • Ballas ZK Rasmussen WL Krieg AM Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA J Immunol 1996, 157:1840-1845. 8757300
    • (1996) J Immunol , vol.157 , pp. 1840-1845
    • Ballas, Z.K.1    Rasmussen, W.L.2    Krieg, A.M.3
  • 31
    • 33645935688 scopus 로고    scopus 로고
    • Comparison of different CpG oligodeoxynucleotide classes for their capability to stimulate human NK cells
    • 10.1002/eji.200535781 16525994
    • Sivori S Carlomagno S Moretta L Moretta A Comparison of different CpG oligodeoxynucleotide classes for their capability to stimulate human NK cells Eur J Immunol 2006, 36:961-967. 10.1002/eji.200535781 16525994
    • (2006) Eur J Immunol , vol.36 , pp. 961-967
    • Sivori, S.1    Carlomagno, S.2    Moretta, L.3    Moretta, A.4
  • 33
    • 28444437011 scopus 로고    scopus 로고
    • Perspectives in asthma: Molecular use of microbial products in asthma prevention and treatment
    • 10.1016/j.jaci.2005.08.050 16337446
    • Racila DM Kline JN Perspectives in asthma: Molecular use of microbial products in asthma prevention and treatment J Allergy Clin Immunol 2005, 116:1202-1205. 10.1016/j.jaci.2005.08.050 16337446
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 1202-1205
    • Racila, D.M.1    Kline, J.N.2
  • 34
    • 33745820869 scopus 로고    scopus 로고
    • TLR9 in health and disease
    • 10.1080/08830180600743107 16818370
    • Vollmer J TLR9 in health and disease Int Rev Immunol 2006, 25:155-181. 10.1080/08830180600743107 16818370
    • (2006) Int Rev Immunol , vol.25 , pp. 155-181
    • Vollmer, J.1
  • 35
    • 17244374001 scopus 로고    scopus 로고
    • Type I interferon dependence of plasmacytoid dendritic cell activation and migration
    • 2213121 15795237 10.1084/jem.20041930
    • Asselin-Paturel C Brizard G Chemin K Boonstra A O'Garra A Vicari A Trinchieri G Type I interferon dependence of plasmacytoid dendritic cell activation and migration J Exp Med 2005, 201:1157-1167. 2213121 15795237 10.1084/jem.20041930
    • (2005) J Exp Med , vol.201 , pp. 1157-1167
    • Asselin-Paturel, C.1    Brizard, G.2    Chemin, K.3    Boonstra, A.4    O'Garra, A.5    Vicari, A.6    Trinchieri, G.7
  • 36
    • 0036587573 scopus 로고    scopus 로고
    • Differential and competitive activation of human immune cells by distinct classes of CpG oligodeoxynucleotide
    • 11994506
    • Gursel M Verthelyi D Gursel I Ishii KJ Klinman DM Differential and competitive activation of human immune cells by distinct classes of CpG oligodeoxynucleotide J Leukoc Biol 2002, 71:813-820. 11994506
    • (2002) J Leukoc Biol , vol.71 , pp. 813-820
    • Gursel, M.1    Verthelyi, D.2    Gursel, I.3    Ishii, K.J.4    Klinman, D.M.5
  • 37
    • 0034933019 scopus 로고    scopus 로고
    • Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells
    • 10.1002/1521-4141(200107)31:7<2154::AID-IMMU2154>3.0.CO;2-U 11449369
    • Krug A Rothenfusser S Hornung V Jahrsdorfer B Blackwell S Ballas ZK Endres S Krieg AM Hartmann G Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells Eur J Immunol 2001, 31:2154-2163. 10.1002/ 1521-4141(200107)31:7<2154::AID-IMMU2154>3.0.CO;2-U 11449369
    • (2001) Eur J Immunol , vol.31 , pp. 2154-2163
    • Krug, A.1    Rothenfusser, S.2    Hornung, V.3    Jahrsdorfer, B.4    Blackwell, S.5    Ballas, Z.K.6    Endres, S.7    Krieg, A.M.8    Hartmann, G.9
  • 39
    • 0038142387 scopus 로고    scopus 로고
    • A role for Toll-like receptors in acquired immunity: Up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells
    • 10.1182/blood-2002-11-3569 12560217
    • Bernasconi NL Onai N Lanzavecchia A A role for Toll-like receptors in acquired immunity: Up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells Blood 2003, 101:4500-4504. 10.1182/blood-2002-11-3569 12560217
    • (2003) Blood , vol.101 , pp. 4500-4504
    • Bernasconi, N.L.1    Onai, N.2    Lanzavecchia, A.3
  • 40
    • 0038236749 scopus 로고    scopus 로고
    • Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells
    • 10.1002/eji.200323813 12778481
    • Hartmann G Battiany J Poeck H Wagner M Kerkmann M Lubenow N Rothenfusser S Endres S Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells Eur J Immunol 2003, 33:1633-1641. 10.1002/eji.200323813 12778481
    • (2003) Eur J Immunol , vol.33 , pp. 1633-1641
    • Hartmann, G.1    Battiany, J.2    Poeck, H.3    Wagner, M.4    Kerkmann, M.5    Lubenow, N.6    Rothenfusser, S.7    Endres, S.8
  • 41
    • 0038341916 scopus 로고    scopus 로고
    • Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions
    • 10.1189/jlb.1202630 12773511
    • Marshall JD Fearon K Abbate C Subramanian S Yee P Gregorio J Coffman RL Van Nest G Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions J Leukoc Biol 2003, 73:781-792. 10.1189/jlb.1202630 12773511
    • (2003) J Leukoc Biol , vol.73 , pp. 781-792
    • Marshall, J.D.1    Fearon, K.2    Abbate, C.3    Subramanian, S.4    Yee, P.5    Gregorio, J.6    Coffman, R.L.7    Van Nest, G.8
  • 42
    • 45949096761 scopus 로고    scopus 로고
    • CpG ODN as a TH1 immune enhancer for prophylactic and therapeutic vaccines
    • In: Hackett CJ, Harn DA, eds Humana Press Inc
    • Krieg A Davis H CpG ODN as a TH1 immune enhancer for prophylactic and therapeutic vaccines. In: Hackett CJ, Harn DA, eds Vaccines Adjuvants: Immunological and Clinical Principles Humana Press Inc 2005:87-110.
    • (2005) Vaccines Adjuvants: Immunological and Clinical Principles , pp. 87-110
    • Krieg, A.1    Davis, H.2
  • 43
    • 11344257404 scopus 로고    scopus 로고
    • CPG 7909, an immunostimulatory TLR9 agonist oligodeoxynucleotide, as adjuvant to Engerix-B HBV vaccine in healthy adults: A double-blind phase I/II study
    • 10.1007/s10875-004-6244-3 15622454
    • Cooper CL Davis HL Morris ML Efler SM Adhami MA Krieg AM Cameron DW Heathcote J CPG 7909, an immunostimulatory TLR9 agonist oligodeoxynucleotide, as adjuvant to Engerix-B HBV vaccine in healthy adults: A double-blind phase I/II study J Clin Immunol 2004, 24:693-701. 10.1007/s10875-004-6244-3 15622454
    • (2004) J Clin Immunol , vol.24 , pp. 693-701
    • Cooper, C.L.1    Davis, H.L.2    Morris, M.L.3    Efler, S.M.4    Adhami, M.A.5    Krieg, A.M.6    Cameron, D.W.7    Heathcote, J.8
  • 44
    • 0037726807 scopus 로고    scopus 로고
    • A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant
    • 10.1016/S0264-410X(03)00045-8 12744879
    • Halperin SA Van Nest G Smith B Abtahi S Whiley H Eiden JJ A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant Vaccine 2003, 21:2461-2467. 10.1016/S0264-410X(03)00045-8 12744879
    • (2003) Vaccine , vol.21 , pp. 2461-2467
    • Halperin, S.A.1    Van Nest, G.2    Smith, B.3    Abtahi, S.4    Whiley, H.5    Eiden, J.J.6
  • 45
    • 25844484501 scopus 로고    scopus 로고
    • CPG 7909 adjuvant improves hepatitis B virus vaccine seroprotection in antiretroviral-treated HIV-infected adults
    • 10.1097/01.aids.0000183514.37513.d2 16135900
    • Cooper CL Davis HL Angel JB Morris ML Elfer SM Seguin I Krieg AM Cameron DW CPG 7909 adjuvant improves hepatitis B virus vaccine seroprotection in antiretroviral-treated HIV-infected adults Aids 2005, 19:1473-1479. 10.1097/01.aids.0000183514.37513.d2 16135900
    • (2005) Aids , vol.19 , pp. 1473-1479
    • Cooper, C.L.1    Davis, H.L.2    Angel, J.B.3    Morris, M.L.4    Elfer, S.M.5    Seguin, I.6    Krieg, A.M.7    Cameron, D.W.8
  • 46
    • 0034547923 scopus 로고    scopus 로고
    • BDCA-2, BDCA-3, and BDCA-4: Three markers for distinct subsets of dendritic cells in human peripheral blood
    • 11086035
    • Dzionek A Fuchs A Schmidt P Cremer S Zysk M Miltenyi S Buck DW Schmitz J BDCA-2, BDCA-3, and BDCA-4: Three markers for distinct subsets of dendritic cells in human peripheral blood J Immunol 2000, 165:6037-6046. 11086035
    • (2000) J Immunol , vol.165 , pp. 6037-6046
    • Dzionek, A.1    Fuchs, A.2    Schmidt, P.3    Cremer, S.4    Zysk, M.5    Miltenyi, S.6    Buck, D.W.7    Schmitz, J.8
  • 47
    • 0030444050 scopus 로고    scopus 로고
    • CpG DNA rescue of murine B lymphoma cells from anti-IgM-induced growth arrest and programmed cell death is associated with increased expression of c-myc and bcl-xL
    • 8943396
    • Yi AK Hornbeck P Lafrenz DE Krieg AM CpG DNA rescue of murine B lymphoma cells from anti-IgM-induced growth arrest and programmed cell death is associated with increased expression of c-myc and bcl-xL J Immunol 1996, 157:4918-4925. 8943396
    • (1996) J Immunol , vol.157 , pp. 4918-4925
    • Yi, A.K.1    Hornbeck, P.2    Lafrenz, D.E.3    Krieg, A.M.4
  • 48
    • 4744368053 scopus 로고    scopus 로고
    • Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation
    • 1782571 15379982 10.1111/j.1365-2567.2004.01962.x
    • Vollmer J Weeratna RD Jurk M Samulowitz U McCluskie MJ Payette P Davis HL Schetter C Krieg AM Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation Immunology 2004, 113:212-223. 1782571 15379982 10.1111/ j.1365-2567.2004.01962.x
    • (2004) Immunology , vol.113 , pp. 212-223
    • Vollmer, J.1    Weeratna, R.D.2    Jurk, M.3    Samulowitz, U.4    McCluskie, M.J.5    Payette, P.6    Davis, H.L.7    Schetter, C.8    Krieg, A.M.9
  • 50
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
    • 10.1016/S0140-6736(01)06102-5 11583749
    • Manns MP McHutchison JG Gordon SC Rustgi VK Shiffman M Reindollar R Goodman ZD Koury K Ling M Albrecht JK Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial Lancet 2001, 358:958-965. 10.1016/S0140-6736(01)06102-5 11583749
    • (2001) Lancet , vol.358 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3    Rustgi, V.K.4    Shiffman, M.5    Reindollar, R.6    Goodman, Z.D.7    Koury, K.8    Ling, M.9    Albrecht, J.K.10
  • 52
    • 0035865054 scopus 로고    scopus 로고
    • Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs
    • 11160295
    • Verthelyi D Ishii KJ Gursel M Takeshita F Klinman DM Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs J Immunol 2001, 166:2372-2377. 11160295
    • (2001) J Immunol , vol.166 , pp. 2372-2377
    • Verthelyi, D.1    Ishii, K.J.2    Gursel, M.3    Takeshita, F.4    Klinman, D.M.5
  • 54
    • 22544450461 scopus 로고    scopus 로고
    • Normal functional capacity in circulating myeloid and plasmacytoid dendritic cells in patients with chronic hepatitis C
    • 10.1086/431523 15995965
    • Longman RS Talal AH Jacobson IM Rice CM Albert ML Normal functional capacity in circulating myeloid and plasmacytoid dendritic cells in patients with chronic hepatitis C J Infect Dis 2005, 192:497-503. 10.1086/431523 15995965
    • (2005) J Infect Dis , vol.192 , pp. 497-503
    • Longman, R.S.1    Talal, A.H.2    Jacobson, I.M.3    Rice, C.M.4    Albert, M.L.5
  • 58
    • 0037562850 scopus 로고    scopus 로고
    • Evidence of viral replication in circulating dendritic cells during hepatitis C virus infection
    • 10.1086/375350 12792872
    • Goutagny N Fatmi A De Ledinghen V Penin F Couzigou P Inchauspe G Bain C Evidence of viral replication in circulating dendritic cells during hepatitis C virus infection J Infect Dis 2003, 187:1951-1958. 10.1086/ 375350 12792872
    • (2003) J Infect Dis , vol.187 , pp. 1951-1958
    • Goutagny, N.1    Fatmi, A.2    De Ledinghen, V.3    Penin, F.4    Couzigou, P.5    Inchauspe, G.6    Bain, C.7
  • 59
    • 4344713084 scopus 로고    scopus 로고
    • Decreased interferon-alpha production and impaired T helper 1 polarization by dendritic cells from patients with chronic hepatitis C
    • 1809147 15320906 10.1111/j.1365-2249.2004.02550.x
    • Murakami H Akbar SM Matsui H Horiike N Onji M Decreased interferon-alpha production and impaired T helper 1 polarization by dendritic cells from patients with chronic hepatitis C Clin Exp Immunol 2004, 137:559-565. 1809147 15320906 10.1111/j.1365-2249.2004.02550.x
    • (2004) Clin Exp Immunol , vol.137 , pp. 559-565
    • Murakami, H.1    Akbar, S.M.2    Matsui, H.3    Horiike, N.4    Onji, M.5
  • 60
    • 22644432777 scopus 로고    scopus 로고
    • Subversion of plasmacytoid and myeloid dendritic cell functions in chronic HCV infection
    • 10.1016/j.imbio.2005.05.018 16164031
    • Szabo G Dolganiuc A Subversion of plasmacytoid and myeloid dendritic cell functions in chronic HCV infection Immunobiology 2005, 210:237-247. 10.1016/j.imbio.2005.05.018 16164031
    • (2005) Immunobiology , vol.210 , pp. 237-247
    • Szabo, G.1    Dolganiuc, A.2
  • 61
    • 1342269881 scopus 로고    scopus 로고
    • Infection and dysfunction of circulating blood dendritic cells and their subsets in chronic hepatitis C virus infection
    • 10.1007/s00535-003-1385-3 15338369
    • Tsubouchi E Akbar SM Horiike N Onji M Infection and dysfunction of circulating blood dendritic cells and their subsets in chronic hepatitis C virus infection J Gastroenterol 2004, 39:754-762. 10.1007/ s00535-003-1385-3 15338369
    • (2004) J Gastroenterol , vol.39 , pp. 754-762
    • Tsubouchi, E.1    Akbar, S.M.2    Horiike, N.3    Onji, M.4
  • 62
    • 0033485756 scopus 로고    scopus 로고
    • Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-alpha inducer in systemic lupus erythematosus
    • 10570325
    • Vallin H Perers A Alm GV Ronnblom L Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-alpha inducer in systemic lupus erythematosus J Immunol 1999, 163:6306-6313. 10570325
    • (1999) J Immunol , vol.163 , pp. 6306-6313
    • Vallin, H.1    Perers, A.2    Alm, G.V.3    Ronnblom, L.4
  • 63
    • 33746365086 scopus 로고    scopus 로고
    • The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells
    • 10.1111/j.0105-2896.2006.00415.x 16903906
    • Shevach EM DiPaolo RA Andersson J Zhao DM Stephens GL Thornton AM The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells Immunol Rev 2006, 212:60-73. 10.1111/j.0105-2896.2006.00415.x 16903906
    • (2006) Immunol Rev , vol.212 , pp. 60-73
    • Shevach, E.M.1    DiPaolo, R.A.2    Andersson, J.3    Zhao, D.M.4    Stephens, G.L.5    Thornton, A.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.