High-throughput sequence typing of T-cell epitope polymorphisms in Plasmodium falciparum circumsporozoite protein

Molecular and Biochemical Parasitology

Volumn 106, Issue 2, 2000, Pages 273-282

  Alloueche, Ali ^a   Silveira, Henrique ^b   Conway, David J ^a   Bojang, Kalifa ^c   Doherty, Tom ^c   Cohen, Joe ^d   Pinder, Margaret ^c   Greenwood, Brian M ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b INSTITUTO DE HIGIENE E MEDICINA TROPICAL   (Portugal)

^c Medical Research Laboratories   (Gambia)

^d GLAXOSMITHKLINE BIOLOGICALS   (Belgium)

Author keywords

Circumsporozoite protein; Malaria; PCR SSOP; RTS,S SBAS2 vaccine; Th2R Th3R polymorphisms

Indexed keywords

EPITOPE; PARASITE ANTIGEN;

ARTICLE; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; T LYMPHOCYTE;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, PROTOZOAN; BASE SEQUENCE; DNA PRIMERS; DNA, PROTOZOAN; EPITOPES; GENE FREQUENCY; HUMANS; MALARIA, FALCIPARUM; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDE PROBES; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROTOZOAN PROTEINS; T-LYMPHOCYTES;

PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 0034005614     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(99)00221-2     Document Type: Article

References (27)

1. Yoshida N., Potocnjak P., Nussenzweig V., Nussenzweig R.S. Biosynthesis of Pb44, the protective antigen of sporozoites of Plasmodium berghei. J. Exp. Med. 154:1981;1225-1236.
2. Nussenzweig V., Nussenzweig R.S. Circumsporozoite proteins of malaria parasites. Cell. 42:1985;401-403.
3. Kumar S., Miller L.H., Quakyi I.A., Keister D.B., Houghten R.A., Maloy W.L. et al. Cytotoxic T cells specific for the circumsporozoite protein of Plasmodium falciparum. Nature. 334:1988;258-260.
4. Krzych U., Lyon J.A., Jareed T., Schneider I., Hollingdale M.R., Gordon D.M. et al. T lymphocytes from volunteers immunized with irradiated Plasmodium falciparum sporozoites recognize liver and blood stage malaria antigens. J. Immunol. 155:1995;4072-4077.
5. Miyahira Y., Garcia-Sastre A., Rodriguez D., Rodriguez J.R., Murata K., Tsuji M. et al. Recombinant viruses expressing a human malaria antigen can elicit potentially protective immune CD8+ responses in mice. Proc. Natl. Acad. Sci. USA. 95:1998;3954-3959.
6. Bharadwaj A., Sharma P., Joshi S.K., Singh B., Chauhan V.S. Induction of protective immune responses by immunization with linear multiepitope peptides based on conserved sequences from Plasmodium falciparum antigens. Infect. Immun. 66:1998;3232-3241.
7. Hollingdale M.R., McCormick C.J., Heal K.G., Taylor-Robinson A.W., Reeve P., Boykins R. et al. Biology of malarial liver stages: implications for vaccine design. Ann. Trop. Med. Parasitol. 92:1998;411-417.
8. Good M.F., Pombo D., Maloy W.L., de la Cruz V.F., Miller L.H., Berzofsky J.A. Parasite polymorphism present within minimal T cell epitopes of Plasmodium falciparum circumsporozoite protein. J. Immunol. 140:1988;1645-1650.
9. de Groot A.S., Johnson A.H., Maloy W.L., Quakyi I.A., Riley E.M., Menon A. et al. Human T cell recognition of polymorphic epitopes from malaria circumsporozoite protein. J. Immunol. 142:1989;4000-4005.
10. Riley E.M., Allen S.J., Bennett S., Thomas P.J., O'Donnell A., Lindsay S.W. et al. Recognition of dominant T cell-stimulating epitopes from the circumsporozoite protein of Plasmodium falciparum and relationship to malaria morbidity in Gambian children. Trans. R. Soc. Trop. Med. Hyg. 84:1990;648-657.
11. Lockyer M., Marsh K., Newbold C.I. Wild isolates of Plasmodium falciparum show extensive polymorphisms in T cell epitopes of the circumsporozoite protein. Mol. Biochem. Parasitol. 37:1989;275-280.
12. Shi Y.P., Alpers M.P., Povoa M.M., Lal A.A. Diversity in the immunodominant determinants of the circumsporozoite protein of Plasmodium falciparum parasites from malaria-endemic regions of Papua New Guinea and Brazil. Am. J. Trop. Med. Hyg. 47:1992;844-851.
13. Doolan D.L., Saul A.L., Good M.L. Geographically restricted heterogeneity of the Plasmodium falciparum CSP: relevance for vaccine development. Infect. Immun. 60:1992;675-682.
14. Jongwutiwes S., Tanabe K., Hughes M.K., Kanbara H., Hughes A.L. Allelic variation in the circumsporozoite protein of Plasmodium falciparum from Thai field isolates. Am. J. Trop. Med. Hyg. 51:1994;659-668.
15. Zevering Y., Khamboonruang C., Good M.F. Effect of polymorphism of sporozoite antigens on T-cell activation. Res. Immunol. 145:1994;469-476.
16. Aidoo M., Lalvani A., Whittle H.C., Hill A.V.S., Robson K.J.H. Recombinant vaccinia viruses for the characterisation of Plasmodium falciparum specific cytotoxic T lymphocytes: recognition of processed antigen despite limited re-stimulation efficacy. Int. Imm. 9:1997;5731-5737.
17. Plebanski M., Gilbert S.C., Schneider J., Hannan C.M., Layton G., Blanchard T. et al. Immune evasion in malaria: altered peptide ligands of the circumsporozoite protein. Eur. J. Imm. 28:1998;4345-4355.
18. Lalvani A., Hurt N., Aidoo M., Kibatala P., Tanner M., Hill A.V.S. Cytotoxic T lymphocytes to Plasmodium falciparum epitopes in an area of intense and perennial transmission in Tanzania. Eur. J. Imm. 26:1996;773-779.
19. Conway D.J., Roper C., Oduola A.M., Arnot D.E., Kremsner P.G., Grobusch M.P. et al. High recombination rate in natural populations of Plasmodium falciparum. Proc. Natl. Acad. Sci. USA. 96:1999;4506-4511.
20. Haywood M., Conway D.J., Weiss H., Metzger W., D'Alessandro U., Snounou G. The epidemiology of multiple Plasmodium falciparum infections. 12. Reduction in the mean number of Plasmodium falciparum genotypes in Gambian children immunised with the malaria vaccine SPf66. Trans. R. Soc. Trop. Med. Hyg. 93:1999;S65-S68.
21. Stoute J.A., Slaoui M., Heppner D.G., Momin P., Kester K.E., Desmons P. et al. A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S/SBAS2. Malaria Vaccine Evaluation Group. N. Engl. J. Med. 336:1997;86-91.
22. Stoute J.A., Kester K.E., Krzych U., Wellde B.T., Hall T., White K. et al. Long-term efficacy and immune responses following immunization with the RTS,S/SBAS2 malaria vaccine. J. Infect. Dis. 178:1998;1139-1144.
23. Dame J.B., Williams J.L., McCucthan T.F.M., Weber J.L., Wirtz R.A., Hockmeyer W.T. et al. Structure of the gene encoding the immunodominant surface antigen of the human malaria parasite Plasmodium falciparum. Science. 225:1984;593-599.
24. Wallace R.B., Shaffer J., Murphy R.F., Bonner J., Hirose T., Itakura K. Hybridization of synthetic oligodeoxyribonucleotides to phi chi 174 DNA: the effect of single base pair mismatch. Nucleic Acids Res. 6:1979;3543-3557.
25. Conner B.J., Reyes A.A., Morin C., Itakura K., Teplitz R.L., Wallace R.B. Detection of sickle cell beta S-globin allele by hybridization with synthetic oligonucleotides. Proc. Natl. Acad. Sci. USA. 80:1983;278-282.
26. Saiki R.K., Bugawan T.L., Horn G.T., Mullis K.B., Erlich H.A. Analysis of enzymatically amplified beta-globin and HLA-DQ alpha DNA with allele-specific oligonucleotide probes. Nature. 324:1986;163-166.
27. Oh S.H., Fleischhauer K., Yang S.Y. Isoelectric focusing subtypes of HLA can be defined by oligonucleotide typing. Tissue Antigens. 41:1993;135-142.