Genetic diversity in the Block 2 region of the merozoite surface protein 1 (MSP-1) of Plasmodium falciparum: Additional complexity and selection and convergence in fragment size polymorphism

Infection, Genetics and Evolution

Volumn 6, Issue 5, 2006, Pages 417-424

  Takala, S L ^a,b   Escalante, A A ^c   Branch, O H ^a,g   Kariuki, S ^d   Biswas, S ^e   Chaiyaroj, S C ^f   Lal, A A ^a  

^a NATL CENTER FOR INFECTIOUS DISEASES   (United States)

^b University of Maryland School of Medicine Center for Vaccine Development   (United States)

^c ARIZONA STATE UNIVERSITY   (United States)

^d KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^e NATIONAL INSTITUTE OF MALARIA RESEARCH   (India)

^f Mahidol University   (Thailand)

^g UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

Author keywords

Genetic diversity; Merozoite protein; Molecular epidemiology; Plasmodium

Indexed keywords

MALARIA VACCINE; MEROZOITE SURFACE PROTEIN 1; MOLECULAR MARKER; PROTOZOAL DNA;

ALLELE; AMINO ACID SEQUENCE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CONVERGENT EVOLUTION; DRUG TARGETING; EPIDEMIOLOGICAL DATA; GENETIC MARKER; GENETIC POLYMORPHISM; GENETIC RECOMBINATION; GENETIC SELECTION; GENETIC VARIABILITY; GEOGRAPHIC DISTRIBUTION; HOST RESISTANCE; HUMAN; IMMUNE RESPONSE; KENYA; MALARIA FALCIPARUM; MOLECULAR CLONING; MOLECULAR EPIDEMIOLOGY; MULTIGENE FAMILY; NATURAL SELECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE TRANSMISSION; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN MOTIF; TANDEM REPEAT; VALIDATION STUDY;

ALLELES; ANIMALS; BASE SEQUENCE; CHILD; GENE FREQUENCY; GEOGRAPHY; HUMANS; INFANT, NEWBORN; KENYA; MALARIA, FALCIPARUM; MEROZOITE SURFACE PROTEIN 1; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; POLYMORPHISM, GENETIC; PROTEIN STRUCTURE, TERTIARY; SELECTION (GENETICS); SEQUENCE HOMOLOGY, NUCLEIC ACID; VARIATION (GENETICS);

PLASMODIUM FALCIPARUM;

EID: 33745339851     PISSN: 15671348     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meegid.2006.01.009     Document Type: Article

References (45)

1. Anderson T.J., Haubold B., Williams J.T., Estrada-Franco J.G., Richardson L., Mollinedo R., Bockarie M., Mokili J., Mharakurwa S., French N., Whitworth J., Velez I.D., Brockman A.H., Nosten F., Ferreira M.U., and Day K.P. Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum. Mol. Biol. Evol. 17 10 (2000) 1467-1482
2. Ariey F., Chalvet W., Hommel D., Peneau C., Hulin A., Mercereau-Puijalon O., Duchemin J.B., Sarthou J.L., Reynes J.M., and Fandeur T. Plasmodium falciparum parasites in French Guiana: limited genetic diversity and high selfing rate. Am. J. Trop. Med. Hyg. 61 6 (1999) 978-985
3. Babiker H.A., Ranford-Cartwright L.C., Currie D., Charlwood J.D., Billingsley P., Teuscher T., and Walliker D. Random mating in a natural population of the malaria parasite Plasmodium falciparum. Parasitology 109 4 (1994) 413-421
4. Babiker H.A., Lines J., Hill W.G., and Walliker D. Population structure of Plasmodium falciparum in villages with different malaria endemicity in east Africa. Am. J. Trop. Med. Hyg. 56 2 (1997) 141-147
5. Bloland P.B., Ruebush T.K., McCormick J.B., Ayisi J., Boriga D.A., Oloo A.J., Beach R., Hawley W., Lal A., Nahlen B., Udhayakumar V., and Campbell C.C. Longitudinal cohort study of the epidemiology of malaria infections in an area of intense malaria transmission I. Description of study site, general methodology, and study population. Am. J. Trop. Med. Hyg. 60 4 (1999) 635-640
6. Branch O.H., Takala S., Kariuki S., Nahlen B.L., Kolczak M., Hawley W., and Lal A.A. Plasmodium falciparum genotypes, low complexity of infection, and resistance to subsequent malaria in participants in the Asembo Bay Cohort Project. Infect. Immun. 69 12 (2001) 7783-7792
7. Cavanagh D.R., Dodoo D., Hviid L., Kurtzhals J.A., Theander T.G., Akanmori B.D., Polley S., Conway D.J., Koram K., and McBride J.S. Antibodies to the N-terminal block 2 of Plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria. Infect. Immun. 72 11 (2004) 6492-6502
8. Conway D.J., and McBride J.S. Population genetics of Plasmodium falciparum within a malaria hyperendemic area. Parasitology 103 1 (1991) 7-16
9. Conway D.J., Roper C., Oduola A.M., Arnot D.E., Kremsner P.G., Grobusch M.P., Curtis C.F., and Greenwood B.M. High recombination rate in natural populations of Plasmodium falciparum. Proc. Natl. Acad. Sci. U.S.A. 96 8 (1999) 4506-4511
10. Conway D.J., Cavanagh D.R., Tanabe K., Roper C., Mikes Z.S., Sakihama N., Bojang K.A., Oduola A.M.J., Kremsner P.G., Arnot D.E., Greenwood B.M., and McBride J.S. A principal target of human immunity to malaria identified by molecular population genetic and immunological analyses. Nat. Med. 6 6 (2000) 689-692
11. Da Silveira L.A., Dorta M.L., Kimura E.A., Katzin A.M., Kawamoto F., Tanabe K., and Ferreira M.U. Allelic diversity and antibody recognition of Plasmodium falciparum merozoite surface protein 1 during hypoendemic malaria transmission in the Brazilian amazon region. Infect. Immun. 67 11 (1999) 5906-5916
12. Escalante A.A., Lal A.A., and Ayala F.J. Genetic polymorphism and natural selection in the malaria parasite Plasmodium falciparum. Genetics 149 1 (1998) 189-202
13. Escalante A.A., Grebert H.M., Chaiyaroj S.C., Magris M., Biswas S., Nahlen B.L., and Lal A.A. Polymorphism in the gene encoding the apical membrane antigen-1 (AMA-1) of Plasmodium falciparum. X. Asembo Bay Cohort Project. Mol. Biochem. Parasitol. 113 2 (2001) 279-287
14. Escalante A.A., Grebert H.M., Isea R., Goldman I.F., Basco L., Magris M., Biswas S., Kariuki S., and Lal A.A. A study of genetic diversity in the gene encoding the circumsporozoite protein (CSP) of Plasmodium falciparum from different transmission areas-XVI. Asembo Bay Cohort Project. Mol. Biochem. Parasitol. 125 1-2 (2002) 83-90
15. Escalante A.A., Cornejo O.E., Rojas A., Udhayakumar V., and Lal A.A. Assessing the effect of natural selection in malaria parasites. Trends Parasitol. 20 8 (2004) 388-395
16. Ewens W.J. The sampling theory of selectively neutral alleles. Theor. Popul. Biol. 3 1 (1972) 87-112
17. Farnert A., Rooth I., Svensson A., Snounou G., and Bjorkman A. Complexity of Plasmodium falciparum infections is consistent over time and protects against clinical disease in Tanzanian children. J. Infect. Dis. 179 4 (1999) 989-995
18. Farnert A., Arez A.P., Babiker H.A., Beck H.P., Benito A., Bjorkman A., Bruce M.C., Conway D.J., Day K.P., Henning L., Mercereau-Puijalon O., Ranford-Cartwright L.C., Rubio J.M., Snounou G., Walliker D., Zwetyenga J., and do Rosario V.E. Genotyping of Plasmodium falciparum infections by PCR: a comparative multicentre study. Trans. R. Soc. Trop. Med. Hyg. 95 2 (2001) 225-232
19. Holder A.A., Blackman M.J., Burghaus P.A., Chappel J.A., Ling I.T., McCallum-Deighton N., and Shai S. A malaria merozoite surface protein (MSP1)-structure, processing and function. Mem. Inst. Oswaldo Cruz 87 Suppl. 3 (1992) 37-42
20. Hughes A.L. Positive selection and interallelic recombination at the merozoite surface antigen-1 (MSA-1) locus of Plasmodium falciparum. Mol. Biol. Evol. 9 3 (1992) 381-393
21. Irion A., Beck H.P., and Felger I. New repeat unit and hot spot of recombination in FC27-type alleles of the gene coding for Plasmodium falciparum merozoite surface protein 2. Mol. Biochem. Parasitol. 90 1 (1997) 367-370
22. Jelinek T., Kilian A.H., Westermeier A., Proll S., Kabagambe G., Nothdurft H.D., von Sonnenburg F., and Loscher T. Population structure of recrudescent Plasmodium falciparum isolates from western Uganda. Trop. Med. Int. Health 4 7 (1999) 476-480
23. Jongwutiwes S., Tanabe K., Nakazawa S., Uemura H., and Kanbara H. Coexistence of GP195 alleles of Plasmodium falciparum in a small endemic area. Am. J. Trop. Med. Hyg. 44 3 (1991) 299-305
24. Konate L., Zwetyenga J., Rogier C., Bischoff E., Fontenille D., Tall A., Spiegel A., Trape J.F., and Mercereau-Puijalon O. Variation of Plasmodium falciparum msp1 block 2 and msp2 allele prevalence and of infection complexity in two neighbouring Senegalese villages with different transmission conditions. Trans. R. Soc. Trop. Med. Hyg. 93 Suppl. 1 (1999) 21-28
25. McCutchan T.F., de la Cruz V.F., Good M.F., and Wellems T.E. Antigenic diversity in Plasmodium falciparum. Prog. Allergy 41 (1988) 173-192
26. McCutchan T.F., Lal A.A., do Rosario V., and Waters A.P. Two types of sequence polymorphism in the circumsporozoite gene of Plasmodium falciparum. Mol. Biochem. Parasitol. 50 1 (1992) 37-45
27. Miller L.H., Roberts T., Shahabuddin M., and McCutchan T.F. Analysis of sequence diversity in the Plasmodium falciparum merozoite surface protein-1 (MSP-1). Mol. Biochem. Parasitol. 59 1 (1993) 1-14
28. Paul R.E., Packer M.J., Walmsley M., Lagog M., Ranford-Cartwright L.C., Paru R., and Day K.P. Mating patterns in malaria parasite populations of Papua New Guinea. Science 269 5231 (1995) 1709-1711
29. Paul R.E., Hackford I., Brockman A., Muller-Graf C., Price R., Luxemburger C., White N.J., Nosten F., and Day K.P. Transmission intensity and Plasmodium falciparum diversity on the northwestern border of Thailand. Am. J. Trop. Med. Hyg. 58 2 (1998) 195-203
30. Polley S.D., Tetteh K.K., Cavanagh D.R., Pearce R.J., Lloyd J.M., Bojang K.A., Okenu D.M., Greenwood B.M., McBride J.S., and Conway D.J. Repeat sequences in block 2 of Plasmodium falciparum merozoite surface protein 1 are targets of antibodies associated with protection from malaria. Infect. Immun. 71 4 (2003) 1833-1842
31. Qari S.H., Shi Y.P., Goldman I.F., Nahlen B.L., Tibayrenc M., and Lal A.A. Predicted and observed alleles of Plasmodium falciparum merozoite surface protein-1 (MSP-1), a potential malaria vaccine antigen. Mol. Biochem. Parasitol. 92 2 (1998) 241-252
32. Rich S.M., Hudson R.R., and Ayala F.J. Plasmodium falciparum antigenic diversity: evidence of clonal population structure. Proc. Natl. Acad. Sci. U.S.A. 94 24 (1997) 13040-13045
33. Robert F., Ntoumi F., Angel G., Candito D., Rogier C., Fandeur T., Sarthou J.L., and Mercereau-Puijalon O. Extensive genetic diversity of Plasmodium falciparum isolates collected from patients with severe malaria in Dakar, Senegal. Trans. R. Soc. Trop. Med. Hyg. 90 6 (1996) 704-711
34. Sakihama N., Kimura M., Hirayama K., Kanda T., Na-Bangchang K., Jongwutiwes S., Conway D., and Tanabe K. Allelic recombination and linkage disequilibrium within Msp-1 of Plasmodium falciparum, the malignant human malaria parasite. Gene 230 1 (1999) 47-54
35. Sakihama N., Matsuo T., Mitamura T., Horii T., Kimura M., Kawabata M., and Tanabe K. Relative frequencies of polymorphisms of variation in Block 2 repeats and 5′ recombinant types of Plasmodium falciparum msp1 alleles. Parasitol. Int. 53 (2004) 59-67
36. Schneider, S., Roessli, D., Excoffier, L., 2000. Arlequin: A software for population genetics data analysis. Geneva, Genetics and Biometry Lab, Dept. of Anthropology, University of Geneva.
37. Slatkin M. An exact test for neutrality based on the Ewens sampling distribution. Genet. Res. 64 1 (1994) 71-74
38. Slatkin M. A correction to the exact test based on the Ewens sampling distribution. Genet. Res. 68 3 (1996) 259-260
39. Snounou G., Zhu X., Siripoon N., Jarra W., Thaithong S., Brown K.N., and Viriyakosol S. Biased distribution of msp1 and msp2 allelic variants in Plasmodium falciparum populations in Thailand. Trans. R. Soc. Trop. Med. Hyg. 94 1 (2000) 65
40. Su X., Ferdig M.T., Huang Y., Huynh C.Q., Liu A., You J., Wootton J.C., and Wellems T.E. A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum. Science 286 5443 (1999) 1351-1353
41. Takala S., Branch O., Escalante A.A., Kariuki S., Wootton J., and Lal A.A. Evidence for intragenic recombination in Plasmodium falciparum: identification of a novel allele family in block 2 of merozoite surface protein-1: Asembo Bay Area Cohort Project XIV. Mol. Biochem. Parasitol. 125 1-2 (2002) 163-171
42. Tanabe K., Mackay M., Goman M., and Scaife J.G. Allelic dimorphism in a surface antigen gene of the malaria parasite Plasmodium falciparum. J. Mol. Biol. 195 2 (1987) 273-287
43. Tibayrenc M., Kjellberg F., Arnaud J., Oury B., Breniere S.F., Darde M.L., and Ayala F.J. Are eukaryotic microorganisms clonal or sexual? A population genetics vantage. Proc. Natl. Acad. Sci. U.S.A. 88 12 (1991) 5129-5133
44. Watterson G.A., and Perlow J. Homozygosity in three-allele populations. Theor. Popul. Biol. 13 2 (1978) 268-275
45. WHO, Roll Back Malaria. What is Malaria? (2002). http://www.who.int/inf-fs/en/InformationSheet01.pdf