Sequence variation in the T-cell epitopes of the Plasmodium falciparum circumsporozoite protein among field isolates is temporally stable: A 5-year longitudinal study in southern Vietnam

Journal of Clinical Microbiology

Volumn 44, Issue 4, 2006, Pages 1229-1235

  Jalloh, Amadu ^a   Van Thien, Huynh ^b   Ferreira, Marcelo U ^c   Ohashi, Jun ^d   Matsuoka, Hiroyuki ^e   Kanbe, Toshio ^a   Kikuchi, Akihiko ^a   Kawamoto, Fumihiko ^f  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Bao Loc General Hospital   (Viet Nam)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d UNIVERSITY OF TOKYO   (Japan)

^e JICHI MEDICAL UNIVERSITY   (Japan)

^f OITA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIRCUMSPOROZOITE PROTEIN; EPITOPE;

ADOLESCENT; ADULT; AGED; ANTIGENIC VARIATION; ARTICLE; BRAZIL; CAMEROON; CHILD; DNA EXTRACTION; EPIDEMIC; EPITOPE MAPPING; GAMBIA; GENE FREQUENCY; GEOGRAPHIC DISTRIBUTION; HUMAN; INDIA; INDONESIA; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MUTATION; MYANMAR; NEIGHBOR JOINING METHOD; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE ISOLATION; PARASITE TRANSMISSION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SEASONAL VARIATION; SENEGAL; SOUTHEAST ASIA; T LYMPHOCYTE; VANUATU; VENEZUELA; VIET NAM;

ANIMALS; DNA, PROTOZOAN; EPITOPES, T-LYMPHOCYTE; HUMANS; LONGITUDINAL STUDIES; PHYLOGENY; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; VARIATION (GENETICS); VIETNAM;

PLASMODIUM FALCIPARUM;

EID: 33645921311     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.44.4.1229-1235.2006     Document Type: Article

References (41)

1. Alloueche, A., H. Silveira, D. J. Conway, K. Bojang, T. Doherty, J. Cohen, M. Pinder, and B. M. Greenwood. 2000. High-throughput sequence typing of T-cell epitope polymorphisms in Plasmodium falciparum circumsporozoite protein. Mol. Biochem. Parasitol. 106:273-282.
2. Alloueche, A., P. Milligan, D. J. Conway, M. Pinder, K. Bojang, T. Doherty, N. Tornieporth, J. Cohen, and B. M. Greenwood. 2003. Protective efficacy of the RTS,S/AS02 Plasmodium falciparum malaria vaccine is not strain specific. Am. J. Trop. Med. Hyg. 68:97-101.
3. Alonso, P. L., J. Sacarlal, J. J. Aponte, A. Leach, E. Macete, J. Milman, I. Mandomando, B. Spiessens, C. Guinovart, M. Espasa, Q. Bassat, P. Aide, O. Ofori-Anyinam, M. M. Navia, S. Corachan, M. Ceuppens, M. C. Dubois, M. A. Demoitie, F. Dubovsky, C. Menendez, N. Tornieporth, W. R. Ballou, R. Thompson, and J. Cohen. 2004. Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial. Lancet 364:1411-1420.
4. Anderson, T. J., B. Haubold, J. T. Williams, J. G. Estrada-Franco, L. Richardson, R. Mollinedo, M. Bockarie, J. Mokili, S. Mharakurwa, N. French, J. Whitworth, I. D. Velez, A. H. Brockman, F. Nosten, M. U. Ferreira, and K. P. Day. 2000. Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum. Mol. Biol. Evol. 17:1467-1482.
5. Bhattacharya, P. R. 1999. Genetic polymorphism in T-cell epitopes of the circumsporozoite protein of Plasmodium falciparum clones and isolates from India. Trans. R. Soc. Trop. Med. Hyg. 93:204-207.
6. Bojang, K. A., P. J. Milligan, M. Pinder, L. Vigneron, A. Alloueche, K. E. Kester, W. R. Ballou, D. J. Conway, W. H. Reece, P. Gothard, L. Yamuah, M. Delchambre, G. Voss, B. M. Greenwood, A. Hill, K. P. McAdam, N. Tornieporth, J. D. Cohen, T. Doherty, and RTS, S Malaria Vaccine Trial Team. 2001. Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial. Lancet 358:1927-1934.
7. 8+ lymphocyte clones: effect of natural polymorphism on T cell recognition and endogenous cognate antigen presentation by liver cells. Eur. J. Immunol. 30:3079-3088.
8. Breman, J. G. 2001. The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden. Am. J. Trop. Med. Hyg. 64:1-11.
9. Conway, D. J., B. M. Greenwood, and J. S. McBride. 1992. Longitudinal study of Plasmodium falciparum polymorphic antigens in a malaria-endemic population. Infect. Immun. 60:1122-1127.
10. Dame, J. B., J. L. Williams, T. F. McCutchan, J. L. Weber, R. A. Wirtz, W. T. Hockmeyer, W. L. Maloy, J. D. Haynes, I. Schneider, D. Roberts, G. S. Sanders, E. P. Reddy, C. L. Diggs, and L. H. Miller. 1984. Structure of the gene encoding the immunodominant surface antigen on the sporozoite of the human malaria parasite Plasmodium falciparum. Science 225:593-599.
11. De La Cruz, V. F., W. L. Maloy, L. H. Miller, M. F. Good, and T. F. McCutchan. 1989. The immunologic significance of variation within malaria circumsporozoite protein sequences. J. Immunol. 142:3568-3575.
12. De Stricker, K., J. Vuust, S. Jepsen, C. Oeuvray, and M. Theisen. 2000. Conservation and heterogeneity of the glutamate-rich protein (GLURP) among field isolates and laboratory lines of Plasmodium falciparum. Mol. Biochem. Parasitol. 111:123-130.
13. Doolan, D. L., A. J. Saul, and M. F. Good. 1992. Geographically restricted heterogeneity of the Plasmodium falciparum circumsporozoite protein: relevance for vaccine development. Infect. Immun. 60:675-682.
14. Escalante, A. A., H. M. Grebert, R. Isea, I. F. Goldman, L. Basco, M. Magris, S. Biswas, S. Kariuki, and A. A. Lal. 2002. A study of genetic diversity in the gene encoding the circumsporozoite protein (CSP) of Plasmodium falciparum from different transmission areas. XVI. Asembo Bay Cohort Project. Mol. Biochem. Parasitol. 125:83-90.
15. Ferreira, M. U., Q. Liu, M. Zhou, M. Kimura, O. Kaneko, H. Van Thien, S. Isomura, K. Tanabe, and F. Kawamoto. 1998. Stable patterns of allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from southern Vietnam. J. Eukaryot. Microbiol. 45:131-136.
16. Ferreira, M. U., W. L. Ribeiro, A. P. Tonon, F. Kawamoto, and S. M. Rich. 2003. Sequence diversity and evolution of the malaria vaccine candidate merozoite surface protein-1 (MSP-1) of Plasmodium falciparum. Gene 304:65-75.
17. Fu, Y. X., and W. H. Li. 1993. Statistical tests of neutrality of mutations. Genetics 133:693-709.
18. Gilbert, S. C., M. Plebanski, S. Gupta, J. Morris, M. Cox, M. Aidoo, D. Kwiatkowski, B. M. Greenwood, H. C. Whittle, and A. V. Hill. 1998. Association of malaria parasite population structure, HLA, and immunological antagonism. Science 279:1173-1177.
19. 8+ T-lymphocyte responses to malaria: identification of new Plasmodium falciparum epitopes by IFN-gamma ELISPOT. Parasite Immunol. 22:501-514.
20. Hudson, R. R., D. D. Boos, and N. L. Kaplan. 1992. A statistical test for detecting population subdivision. Mol. Biol. Evol. 9:138-151.
21. Hudson, R. R., M. Slatkin, and W. P. Maddison. 1992. Estimation of levels of gene flow from DNA sequence data. Genetics 132:583-589.
22. Hughes, A. L. 1991. Circumsporozoite protein genes of malaria parasites (Piasmodium spp.): evidence for positive selection on immunogenic regions. Genetics 127:345-353.
23. Hughes, M. K., and A. L. Hughes. 1995. Natural selection on Plasmodium surface proteins. Mol. Biochem. Parasitol. 71:99-113.
24. Jongwutiwes, S., K. Tanabe, M. K. Hughes, H. Kanbara, and A. L. Hughes. 1994. Allelic variation in the circumsporozoite protein of Plasmodium falciparum of Thai field isolates. Am. J. Trop. Med. Hyg. 51:659-668.
25. Kumar, S., K. Tamura, I. B. Jakobsen, and M. Nei. 2001. MEGA2: molecular evolutionary genetics analysis software. Bioinformatics 17:1244-1245.
26. Kumkhaek, C., K. Phra-ek, P. Singhasivanon, S. Looareesuwan, C. Hirunpetcharat, A. Brockman, A. C. Gruner, N. Lebrun, L. Renia, F. Nosten, G. Snounou, and S. Khusmith. 2004. A survey of the Th2R and Th3R allelic variants in the circumsporozoite protein gene of Plasmodium falciparum parasites from western Thailand. Southeast Asian J. Trop. Med. Public Health 35:281-287.
27. Lockyer, M. J., K. Marsh, and C. I. Newbold. 1989. Wild isolates of Plasmodium falciparum show extensive polymorphism in T cell epitopes of the circumsporozoite protein. Mol. Biochem. Parasitol. 37:275-280.
28. Lynch, M., and T. J. Crease. 1990. The analysis of population survey data on DNA sequence variation. Mol. Biol. Evol. 7:377-394.
29. Nardin, E. H., G. A. Oliveira, J. M. Calvo-Calle, Z. R. Castro, R. S. Nussenzweig, B. Schmeckpeper, B. F. Hall, C. Diggs, S. Bodison, and R. Edelman. 2000. Synthetic malaria peptide vaccine elicits high levels of antibodies in vaccinees of defined HLA genotypes. J. Infect. Dis. 182:1486-1496.
30. Nei, M. 1987. Molecular evolutionary genetics. Columbia University Press, New York, N.Y.
31. Rathore, D., and T. F. McCutchan. 2000. The cytotoxic T-lymphocyte epitope of the Plasmodium falciparum cireumsporozoite protein also modulates the efficiency of receptor-ligand interaction with hepatocytes. Infect. Immun. 68:740-743.
32. Rozas, J., J. C. Sanchez-DelBarrio, X. Messeguer, and R. Rozas. 2003. DnaSP, DNA polymorphism analyses by the coalescent and other methods. Bioinformatics 19:2496-2497.
33. Safitri, I., A. Jalloh, I. S. Tantular, S. Pusarawati, T. T. Win, Q. Liu, M. U. Ferreira, Y. P. Dachlan, T. Horii, and F. Kawamoto. 2003. Sequence diversity in the amino-terminal region of the malaria-vaccine candidate serine repeat antigen in natural Plasmodium falciparum populations. Parasitol. Int. 52:117-131.
34. Shi, Y. P., M. P. Alpers, M. M. Povoa, and A. A. Lal. 1992. Diversity in the immunodominant determinants of the circumsporozoite protein of Plasmodium falciparum parasites from malaria-endemic regions of Papua New Guinea and Brazil. Am. J. Trop. Med. Hyg. 47:844-851.
35. Tajima, F. 1989. Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123:585-595.
36. Tanabe, K., N. Sakihama, and A. Kaneko. 2004. Stable SNPs in malaria antigen genes in isolated populations. Science 303:493.
37. 8+ CTL epitopc in naturally exposed Kenyan adults. Eur. J. Immunol. 27:1952-1957.
38. Verle, P., T. C. Tuy, T. T. Lieu, A. Kongs, and M. Coosemans. 1998. New challenges for malaria control in northern Vietnam. Res. Rev. Parasitol. 58:169-174.
39. Wang, R., D. L. Doolan, T. P. Le, R. C. Hedstrom, K. M. Coonan, Y. Charoenvit, T. R. Jones, P. Hobart, M. Margalith, J. Ng, W. R. Weiss, M. Sedegah, C. de Taisne, J. A. Norman, and S. L. Huffman. 1998. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science 282:476-480.
40. Yoshida, N., R. S. Nussenzweig, P. Potocnjak, V. Nussenzweig, and M. Aikawa. 1980. Hybridoma produces protective antibodies directed against the sporozoite stage of malaria parasite. Science 207:71-73.
41. Zavala, F., A. H. Cochrane, E. H. Nardin, R. S. Nussenzweig, and V. Nussenzweig. 1983. Circumsporozoite proteins of malaria parasites contain a single immunodominant region with two or more identical epitopes. J. Exp. Med. 157:1947-1957.