-
1
-
-
45449083644
-
-
For the synthesis of medium-sized ring by Heck type cyclization, see:
-
For the synthesis of medium-sized ring by Heck type cyclization, see:
-
-
-
-
8
-
-
34250693713
-
-
Joucla L., Popowycz F., Lozach O., Meijer L., and Joseph B. Helv. Chim. Acta 90 (2007) 753-763
-
(2007)
Helv. Chim. Acta
, vol.90
, pp. 753-763
-
-
Joucla, L.1
Popowycz, F.2
Lozach, O.3
Meijer, L.4
Joseph, B.5
-
9
-
-
45449084636
-
-
For the examples of palladium-mediated inter- and intramolecular aryl-aryl couplings, see:
-
For the examples of palladium-mediated inter- and intramolecular aryl-aryl couplings, see:
-
-
-
-
10
-
-
33846918696
-
-
and further references cited therein
-
Alberico D., Scott M.E., and Lautens M. Chem. Rev. 107 (2007) 174-238 and further references cited therein
-
(2007)
Chem. Rev.
, vol.107
, pp. 174-238
-
-
Alberico, D.1
Scott, M.E.2
Lautens, M.3
-
18
-
-
45449118298
-
-
For the Pd-mediated arylation and Heck type cyclization involving indole moiety, see:
-
For the Pd-mediated arylation and Heck type cyclization involving indole moiety, see:
-
-
-
-
19
-
-
31544479559
-
-
Routier S., Merour J.-Y., Dias N., Lansiaux A., Bailly C., Lozach O., and Meijer L. J. Med. Chem. 49 (2006) 789-799
-
(2006)
J. Med. Chem.
, vol.49
, pp. 789-799
-
-
Routier, S.1
Merour, J.-Y.2
Dias, N.3
Lansiaux, A.4
Bailly, C.5
Lozach, O.6
Meijer, L.7
-
20
-
-
33845534545
-
-
Putey A., Joucla L., Picot L., Besson T., and Joseph B. Tetrahedron 63 (2007) 867-879
-
(2007)
Tetrahedron
, vol.63
, pp. 867-879
-
-
Putey, A.1
Joucla, L.2
Picot, L.3
Besson, T.4
Joseph, B.5
-
22
-
-
0010372638
-
-
Grigg R., Sridharan V., Stevenson P., Sukirthalingam S., and Worakun T. Tetrahedron 46 (1990) 4003-4018
-
(1990)
Tetrahedron
, vol.46
, pp. 4003-4018
-
-
Grigg, R.1
Sridharan, V.2
Stevenson, P.3
Sukirthalingam, S.4
Worakun, T.5
-
26
-
-
45449109216
-
-
For the Pd-mediated arylation of imidazole, benzimidazole, purine, and related azole derivatives, see:
-
For the Pd-mediated arylation of imidazole, benzimidazole, purine, and related azole derivatives, see:
-
-
-
-
29
-
-
32144434941
-
-
Bellina F., Cauteruccio S., Mannina L., Rossi R., and Viel S. Eur. J. Org. Chem. (2006) 693-703
-
(2006)
Eur. J. Org. Chem.
, pp. 693-703
-
-
Bellina, F.1
Cauteruccio, S.2
Mannina, L.3
Rossi, R.4
Viel, S.5
-
30
-
-
18744369931
-
-
Bellina F., Cauteruccio S., Mannina L., Rossi R., and Viel S. J. Org. Chem. 70 (2005) 3997-4005
-
(2005)
J. Org. Chem.
, vol.70
, pp. 3997-4005
-
-
Bellina, F.1
Cauteruccio, S.2
Mannina, L.3
Rossi, R.4
Viel, S.5
-
33
-
-
45449101534
-
-
For the general review on Baylis-Hillman reaction, see:
-
For the general review on Baylis-Hillman reaction, see:
-
-
-
-
35
-
-
0000892247
-
-
Paquette L.A. (Ed), John Wiley & Sons, New York, NY
-
Ciganek E. In: Paquette L.A. (Ed). Organic Reactions Vol. 51 (1997), John Wiley & Sons, New York, NY 201-350
-
(1997)
Organic Reactions
, vol.51
, pp. 201-350
-
-
Ciganek, E.1
-
39
-
-
41649086484
-
-
and further references cited therein
-
Singh V., and Batra S. Tetrahedron 64 (2008) 4511-4574 and further references cited therein
-
(2008)
Tetrahedron
, vol.64
, pp. 4511-4574
-
-
Singh, V.1
Batra, S.2
-
40
-
-
45449091957
-
-
For the Pd-mediated reactions involving Baylis-Hillman adducts, see:
-
For the Pd-mediated reactions involving Baylis-Hillman adducts, see:
-
-
-
-
42
-
-
33646112175
-
-
Coelho F., Veronese D., Pavam C.H., de Paula V.I., and Buffon R. Tetrahedron 62 (2006) 4563-4572
-
(2006)
Tetrahedron
, vol.62
, pp. 4563-4572
-
-
Coelho, F.1
Veronese, D.2
Pavam, C.H.3
de Paula, V.I.4
Buffon, R.5
-
43
-
-
33748676656
-
-
Ribiere P., Declerck V., Nedellec Y., Yadav-Bhatnagar N., Martinez J., and Lamaty F. Tetrahedron 62 (2006) 10456-10466
-
(2006)
Tetrahedron
, vol.62
, pp. 10456-10466
-
-
Ribiere, P.1
Declerck, V.2
Nedellec, Y.3
Yadav-Bhatnagar, N.4
Martinez, J.5
Lamaty, F.6
-
44
-
-
33846062119
-
-
Declerck V., Ribiere P., Nedellec Y., Allouchi H., Martinez J., and Lamaty F. Eur. J. Org. Chem. (2007) 201-208
-
(2007)
Eur. J. Org. Chem.
, pp. 201-208
-
-
Declerck, V.1
Ribiere, P.2
Nedellec, Y.3
Allouchi, H.4
Martinez, J.5
Lamaty, F.6
-
45
-
-
45449109809
-
-
For our recent papers on the Pd-mediated reactions using the Baylis-Hillman adducts, see:
-
For our recent papers on the Pd-mediated reactions using the Baylis-Hillman adducts, see:
-
-
-
-
48
-
-
35748950143
-
-
and further references cited therein on the synthesis and biological activities of benzoazepino[2,1-a]isoindole moiety-containing compounds
-
Gowrisankar S., Lee H.S., Lee K.Y., Lee J.-E., and Kim J.N. Tetrahedron Lett. 48 (2007) 8619-8622 and further references cited therein on the synthesis and biological activities of benzoazepino[2,1-a]isoindole moiety-containing compounds
-
(2007)
Tetrahedron Lett.
, vol.48
, pp. 8619-8622
-
-
Gowrisankar, S.1
Lee, H.S.2
Lee, K.Y.3
Lee, J.-E.4
Kim, J.N.5
-
50
-
-
45449088131
-
-
For the preparation of benzoazepino[1,2-a]indole derivatives as inhibitors of hepatitis C virus (HCV) replication, see:
-
For the preparation of benzoazepino[1,2-a]indole derivatives as inhibitors of hepatitis C virus (HCV) replication, see:
-
-
-
-
51
-
-
45449116910
-
-
Hudyma, T. W.; Zheng, X.; He, F.; Ding, M.; Bergstrom, C. P.; Hewawasam, P.; Martin, S. W.; Gentles, R. G. WO 2007092000, 2007;
-
Hudyma, T. W.; Zheng, X.; He, F.; Ding, M.; Bergstrom, C. P.; Hewawasam, P.; Martin, S. W.; Gentles, R. G. WO 2007092000, 2007;
-
-
-
-
52
-
-
77953934414
-
-
Chem. Abstr. 147 (2007) 277782
-
(2007)
Chem. Abstr.
, vol.147
, pp. 277782
-
-
-
53
-
-
45449106178
-
-
Meanwell, N. A.; Gentles, R. G.; Ding, M.; Bender, J. A.; Kadow, J. F.; Hewawasam, P.; Hudyma, T. W.; Zheng, X. US 2007,184,024, 2007;
-
Meanwell, N. A.; Gentles, R. G.; Ding, M.; Bender, J. A.; Kadow, J. F.; Hewawasam, P.; Hudyma, T. W.; Zheng, X. US 2007,184,024, 2007;
-
-
-
-
54
-
-
45449098271
-
-
Chem. Abstr. 147 (2007) 257667
-
(2007)
Chem. Abstr.
, vol.147
, pp. 257667
-
-
-
55
-
-
45449085045
-
-
Bergstrom, C. P.; Bender, J. A.; Gentles, R. G.; Hewawasam, P.; Hudyma, T. W.; Kadow, J. F.; Martin, S. W.; Regueiro-Ren, A.; Yeung, K. -S.; Tu, Y.; Grant-Young, K. A.; Zheng, X. WO 2007033175, 2007;
-
Bergstrom, C. P.; Bender, J. A.; Gentles, R. G.; Hewawasam, P.; Hudyma, T. W.; Kadow, J. F.; Martin, S. W.; Regueiro-Ren, A.; Yeung, K. -S.; Tu, Y.; Grant-Young, K. A.; Zheng, X. WO 2007033175, 2007;
-
-
-
-
56
-
-
84872469427
-
-
Chem. Abstr. 146 (2007) 358820
-
(2007)
Chem. Abstr.
, vol.146
, pp. 358820
-
-
-
57
-
-
45449105005
-
-
Bergstrom, C. P.; Martin, S. W.; Hudyma, T. W. US 2007,185,083, 2007;
-
Bergstrom, C. P.; Martin, S. W.; Hudyma, T. W. US 2007,185,083, 2007;
-
-
-
-
58
-
-
84872435793
-
-
Chem. Abstr. 147 (2007) 235031
-
(2007)
Chem. Abstr.
, vol.147
, pp. 235031
-
-
-
59
-
-
45449099500
-
-
Gentles, R. G.; Ding, M.; Hewawasam, P. US 2007,275,930, 2007;
-
Gentles, R. G.; Ding, M.; Hewawasam, P. US 2007,275,930, 2007;
-
-
-
-
60
-
-
77949782312
-
-
Chem. Abstr. 148 (2007) 11085
-
(2007)
Chem. Abstr.
, vol.148
, pp. 11085
-
-
-
61
-
-
45449093204
-
-
For the synthesis and biological importance of 1,7-annulated indole derivatives, see:
-
For the synthesis and biological importance of 1,7-annulated indole derivatives, see:
-
-
-
-
62
-
-
2442471732
-
-
Al-awar R.S., Ray J.E., Hecker K.A., Huang J., Waid P.P., Shih C., Brooks H.B., Spencer C.D., Watkins S.A., Patel B.R., Stamm N.B., Ogg C.A., Schultz R.M., Considine E.L., Faul M.M., Sullivan K.A., Kolis S.P., Grutsch J.L., and Joseph S. Bioorg. Med. Chem. Lett. 14 (2004) 3217-3220
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 3217-3220
-
-
Al-awar, R.S.1
Ray, J.E.2
Hecker, K.A.3
Huang, J.4
Waid, P.P.5
Shih, C.6
Brooks, H.B.7
Spencer, C.D.8
Watkins, S.A.9
Patel, B.R.10
Stamm, N.B.11
Ogg, C.A.12
Schultz, R.M.13
Considine, E.L.14
Faul, M.M.15
Sullivan, K.A.16
Kolis, S.P.17
Grutsch, J.L.18
Joseph, S.19
-
63
-
-
2442417541
-
-
Zhu G., Conner S.E., Zhou X., Chan H.-K., Shih C., Engler T.A., Al-awar R.S., Brooks H.B., Watkins S.A., Spencer C.D., Schultz R.M., Dempsey J.A., Considine E.L., Patel B.R., Ogg C.A., Vasudevan V., and Lytle M.L. Bioorg. Med. Chem. Lett. 14 (2004) 3057-3061
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 3057-3061
-
-
Zhu, G.1
Conner, S.E.2
Zhou, X.3
Chan, H.-K.4
Shih, C.5
Engler, T.A.6
Al-awar, R.S.7
Brooks, H.B.8
Watkins, S.A.9
Spencer, C.D.10
Schultz, R.M.11
Dempsey, J.A.12
Considine, E.L.13
Patel, B.R.14
Ogg, C.A.15
Vasudevan, V.16
Lytle, M.L.17
-
64
-
-
0027131604
-
-
Van Wijngaarden I., Hamminga D., van Hes R., Standaar P.J., Tipker J., Tulp M.Th., Mol F., Olivier B., and de Jonge A. J. Med. Chem. 36 (1993) 3693-3699
-
(1993)
J. Med. Chem.
, vol.36
, pp. 3693-3699
-
-
Van Wijngaarden, I.1
Hamminga, D.2
van Hes, R.3
Standaar, P.J.4
Tipker, J.5
Tulp, M.Th.6
Mol, F.7
Olivier, B.8
de Jonge, A.9
-
65
-
-
0017236435
-
-
Toscano L., Grisanti G., Fioriello G., Seghetti E., Bianchetti A., Bossoni G., and Riva M. J. Med. Chem. 19 (1976) 208-213
-
(1976)
J. Med. Chem.
, vol.19
, pp. 208-213
-
-
Toscano, L.1
Grisanti, G.2
Fioriello, G.3
Seghetti, E.4
Bianchetti, A.5
Bossoni, G.6
Riva, M.7
-
66
-
-
45449116719
-
-
For the synthesis and biological importance of tetracyclic indole derivatives, see:
-
For the synthesis and biological importance of tetracyclic indole derivatives, see:
-
-
-
-
68
-
-
33845356771
-
-
Ikegashira K., Oka T., Hirashima S., Noji S., Yamanaka H., Hara Y., Adachi T., Tsuruha J.-I., Doi S., Hase Y., Noguchi T., Ando I., Ogura N., Ikeda S., and Hashimoto H. J. Med. Chem. 49 (2006) 6950-6953
-
(2006)
J. Med. Chem.
, vol.49
, pp. 6950-6953
-
-
Ikegashira, K.1
Oka, T.2
Hirashima, S.3
Noji, S.4
Yamanaka, H.5
Hara, Y.6
Adachi, T.7
Tsuruha, J.-I.8
Doi, S.9
Hase, Y.10
Noguchi, T.11
Ando, I.12
Ogura, N.13
Ikeda, S.14
Hashimoto, H.15
-
69
-
-
0034704888
-
-
Faust R., Garratt P.J., Jones R., Yeh L.-K., Tsotinis A., Panoussopoulou M., Calogeropoulou T., Teh M.-T., and Sugden D. J. Med. Chem. 43 (2000) 1050-1061
-
(2000)
J. Med. Chem.
, vol.43
, pp. 1050-1061
-
-
Faust, R.1
Garratt, P.J.2
Jones, R.3
Yeh, L.-K.4
Tsotinis, A.5
Panoussopoulou, M.6
Calogeropoulou, T.7
Teh, M.-T.8
Sugden, D.9
-
70
-
-
0037431390
-
-
Rivara S., Mor M., Silva C., Zuliani V., Vacondio F., Spadoni G., Bedini A., Tarzia G., Lucini V., Pannacci M., Fraschini F., and Plazzi P.V. J. Med. Chem. 46 (2003) 1429-1439
-
(2003)
J. Med. Chem.
, vol.46
, pp. 1429-1439
-
-
Rivara, S.1
Mor, M.2
Silva, C.3
Zuliani, V.4
Vacondio, F.5
Spadoni, G.6
Bedini, A.7
Tarzia, G.8
Lucini, V.9
Pannacci, M.10
Fraschini, F.11
Plazzi, P.V.12
-
73
-
-
9144224945
-
-
Kunick C., Lauenroth K., Wieking K., Xie X., Schultz C., Gussio R., Zaharevitz D., Leost M., Meijer L., Weber A., Jorgensen F.S., and Lemcke T. J. Med. Chem. 47 (2004) 22-36
-
(2004)
J. Med. Chem.
, vol.47
, pp. 22-36
-
-
Kunick, C.1
Lauenroth, K.2
Wieking, K.3
Xie, X.4
Schultz, C.5
Gussio, R.6
Zaharevitz, D.7
Leost, M.8
Meijer, L.9
Weber, A.10
Jorgensen, F.S.11
Lemcke, T.12
-
74
-
-
0033798031
-
-
Leost M., Schultz C., Link A., Wu Y.-Z., Biernat J., Mandelkow E.-M., Bibb J.A., Snyder G.L., Greengard P., Zaharevitz D.W., Gussio R., Senderowicz A.M., Sausville E.A., Kunick C., and Meijer L. Eur. J. Biochem. 267 (2000) 5983-5994
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 5983-5994
-
-
Leost, M.1
Schultz, C.2
Link, A.3
Wu, Y.-Z.4
Biernat, J.5
Mandelkow, E.-M.6
Bibb, J.A.7
Snyder, G.L.8
Greengard, P.9
Zaharevitz, D.W.10
Gussio, R.11
Senderowicz, A.M.12
Sausville, E.A.13
Kunick, C.14
Meijer, L.15
-
75
-
-
41849116324
-
-
Stukenbrock H., Mussmann R., Geese M., Ferandin Y., Lozach O., Lemcke T., Kegel S., Lomow A., Burk U., Dohrmann C., Meijer L., Austen M., and Kunick C. J. Med. Chem. 51 (2008) 2196-2207
-
(2008)
J. Med. Chem.
, vol.51
, pp. 2196-2207
-
-
Stukenbrock, H.1
Mussmann, R.2
Geese, M.3
Ferandin, Y.4
Lozach, O.5
Lemcke, T.6
Kegel, S.7
Lomow, A.8
Burk, U.9
Dohrmann, C.10
Meijer, L.11
Austen, M.12
Kunick, C.13
-
76
-
-
45449109005
-
-
For the synthesis of eight-membered cyclic compounds, see:
-
For the synthesis of eight-membered cyclic compounds, see:
-
-
-
-
80
-
-
37549028018
-
-
Voskressensky L.G., Listratova A.V., Borisova T.N., Alexandrov G.G., and Varlamov A.V. Eur. J. Org. Chem. (2007) 6106-6117
-
(2007)
Eur. J. Org. Chem.
, pp. 6106-6117
-
-
Voskressensky, L.G.1
Listratova, A.V.2
Borisova, T.N.3
Alexandrov, G.G.4
Varlamov, A.V.5
-
82
-
-
34247529894
-
-
Panayides J.-L., Pathak R., Panagiotopoulos H., Davids H., Fernandes M.A., de Koning C.B., and van Otterlo W.A.L. Tetrahedron 63 (2007) 4737-4747
-
(2007)
Tetrahedron
, vol.63
, pp. 4737-4747
-
-
Panayides, J.-L.1
Pathak, R.2
Panagiotopoulos, H.3
Davids, H.4
Fernandes, M.A.5
de Koning, C.B.6
van Otterlo, W.A.L.7
-
83
-
-
33744512129
-
-
Voskressensky L.G., Borisova T.N., Listratova A.V., Kulikova L.N., Titov A.A., and Varlamov A.V. Tetrahedron Lett. 47 (2006) 4585-4589
-
(2006)
Tetrahedron Lett.
, vol.47
, pp. 4585-4589
-
-
Voskressensky, L.G.1
Borisova, T.N.2
Listratova, A.V.3
Kulikova, L.N.4
Titov, A.A.5
Varlamov, A.V.6
-
85
-
-
41549106574
-
-
Dieltiens N., Stevens C.V., Masschelein K., Hennebel G., and der Jeught S.V. Tetrahedron 64 (2008) 4295-4303
-
(2008)
Tetrahedron
, vol.64
, pp. 4295-4303
-
-
Dieltiens, N.1
Stevens, C.V.2
Masschelein, K.3
Hennebel, G.4
der Jeught, S.V.5
-
86
-
-
33645390150
-
-
Seto M., Aikawa K., Miyamoto N., Aramaki Y., Kanzaki N., Takashima K., Kuze Y., Iizawa Y., Baba M., and Shiraishi M. J. Med. Chem. 49 (2006) 2037-2048
-
(2006)
J. Med. Chem.
, vol.49
, pp. 2037-2048
-
-
Seto, M.1
Aikawa, K.2
Miyamoto, N.3
Aramaki, Y.4
Kanzaki, N.5
Takashima, K.6
Kuze, Y.7
Iizawa, Y.8
Baba, M.9
Shiraishi, M.10
|