Investigation of the role of a second conserved serine in carboxylesterases via site-directed mutagenesis

Archives of Biochemistry and Biophysics

Volumn 430, Issue 2, 2004, Pages 247-255

  Stok, Jeanette E ^a   Goloshchapov, Andrey ^a   Song, Cheng ^a   Wheelock, Craig E ^a   Derbel, Maher B H ^a   Morisseau, Christophe ^a   Hammock, Bruce D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Carboxylesterase; Catalytic triad; Serine; Site directed mutagenesis

Indexed keywords

ALANINE; CARBAMIC ACID DERIVATIVE; CARBARIL; CARBOXYLESTERASE; CYSTEINE; GLUTAMIC ACID; GLYCINE; LONG CHAIN FATTY ACID COENZYME A LIGASE; MUTANT PROTEIN; SERINE;

CATALYSIS; CONFERENCE PAPER; CRYSTAL STRUCTURE; DEACYLATION; ENZYME MECHANISM; HYDROLYSIS; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CARBARYL; CARBOXYLIC ESTER HYDROLASES; CATALYSIS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; MUTATION; RATS; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP;

FELIS CATUS;

EID: 4544387955     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.abb.2004.06.020     Document Type: Conference Paper

References (37)

1. B.A. Thomas, W.B. Church, T.R. Lane, and B.D. Hammock Proteins 34 1999 184 196
2. T. Satoh, and M. Hosokawa Ann. Rev. Pharm. Toxicol. 38 1998 257 288
3. R.M. Krupka Biochemistry 5 1966 1983 1988
4. R. Roskoski Biochemistry 13 1974 5141 5144
5. K. MacPhee-Quigley, P. Taylor, and S. Taylor J. Biol. Chem. 260 1985 12185 12189
6. G. Gibney, S. Camp, M. Dionne, K. Mac-Phee-Quigley, and P. Taylor Proc. Natl. Acad. Sci. USA 87 1990 7546 7550
7. J.L. Sussman, M. Harel, F. Frolow, C. Oefner, A. Goldman, L. Toker, and I. Silman Science 253 1991 872 879
8. A. Shafferman, C. Kronman, Y. Flashner, M. Leitner, H. Grosfeld, A. Ordentlich, Y. Gozes, S. Cohen, N. Ariel, D. Barak, M. Harel, I. Silman, J.L. Sussman, and B. Velan J. Biol. Chem. 267 1992 17640 17648
9. J. Emmerich, O.U. Beg, J. Peterson, L. Previato, J.D. Brunzell, H.B.J. Brewer, and S. Santamarina-Fojo J. Biol. Chem. 267 1992 4161 4165
10. M. Haruki, Y. Oohashi, S. Mizuguchi, Y. Matsuo, M. Morikawa, and S. Kanaya FEBS Lett. 454 1999 262 266
11. P. Lohse, S. Chahrokh-Zadeh, P. Lohse, and D. Seidel J. Lipid Res. 38 1997 892 903
12. V.K. Ward, B.C. Bonning, Q. Huang, T. Shiotsuki, V.N. Griffeth, and B.D. Hammock Int. J. Biochem. 24 1992 1933 1941
13. P.A. Frey, S.A. Whitt, and J.B. Tobin Science 264 1994 1927 1930
14. A. Warshel, A. Papazyan, and P.A. Kollman Science 269 1995 102 106
15. C. Viragh, T.K. Harris, P.M. Reddy, M.A. Massiah, A.S. Mildvan, and I.M. Kovach Biochemistry 39 2000 16200 16205
16. M.A. Massiah, C. Viragh, P.M. Reddy, I.M. Kovach, J. Johnson, T.L. Rosenberry, and A.S. Mildvan Biochemistry 40 2001 5682 5690
17. M. Robbi, H. Beaufay, and J.-N. Octave Biochem. J. 269 1990 451 458
18. R. Mentlein, A. Ronai, M. Robbi, E. Heymann, and O.v. Deimling Biochim. Biophys. Acta 913 1987 27 38
19. M. Hosokawa, T. Maki, and T. Satoh Arch. Biochem. Biophys. 277 1990 219 227
20. D.R. O'Reilly L.K. Miller V.A. Luckow Baculovirus Expression vectors: A Laboratory Manual 1994 W.H. Freeman and Co. New York 347
21. T.L. Huang, T. Shiotsuki, T. Uematsu, B. Borhan, Q.X. Li, and B.D. Hammock Pharm. Res. 13 1996 1495 1500
22. A. Ljungquist, and K.B. Augustinsson Eur. J. Biochem. 23 1971 303 313
23. C.E. Wheelock, T.F. Severson, and B.D. Hammock Chem. Res. Toxicol. 14 2001 1563 1572
24. S.J. Gee, T. Miyamoto, M.H. Goodrow, D. Buster, and B.D. Hammock J. Agric. Food Chem. 36 1988 863 870
25. A.R. Main E. Hodgson F.E. Guthrie Introduction to Biochemical Toxicology 1980 Elsevier New York 193 223
26. M.E. McGrath, J.R. Vasquez, C.S. Craik, A.S. Yang, B. Honig, and R.J. Fletterick Biochemistry 31 1992
27. M.M. Krem, and E. Di Cera EMBO J. 20 2001 3036 3045
28. G. Dodson, and A. Wlodawer Trends Biochem. Sci. 23 1998 347 352
29. L. Hedstrom Chem. Rev. 102 2002 4501 4523
30. D.M. Epstein, and R.H. Abeles Biochemistry 31 1992 11216 11223
31. M.M. Krem, S. Prasad, and E. Di Cera J. Biol. Chem. 277 2002 40260 40294
32. Z.S. Derewenda, U. Derewenda, and P.M. Kobos J. Mol. Biol. 241 1994
33. P.A. Molina, R.S. Sikorski, and J.H. Jensen Theor. Chem. Accounts 109 2003 100 107
34. C.B. Millard, G. Koellner, A. Ordentlich, A. Shafferman, I. Silman, and J.L. Sussman J. Am. Chem. Soc. 121 1999 9883 9884
35. R.N. Armstrong, and C.S. Cassidy Drug Metab. Rev. 32 2000 327 338
36. S. Bencharit, C.L. Morton, J.L. Hyatt, P. Kuhn, M.K. Danks, P.M. Potter, and M.R. Redinbo Chem. Biol. 10 2003 341 349
37. W.W. Bachovchin Magn. Reson. Chem. 39 2001 S199 S213