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Volumn 287, Issue 4 31-4, 2004, Pages

Anti-inflammatory effects of resveratrol in lung epithelial cells: Molecular mechanisms

Author keywords

Inducible nitric oxide synthase; Quercetin; Red wine

Indexed keywords

ACETYLCYSTEINE; CYCLIC AMP; CYCLOOXYGENASE 2; DEOXYRHAPONTIN; DEXAMETHASONE; ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ANTAGONIST; GLUCOCORTICOID; GLUCOCORTICOID ANTAGONIST; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GW 466471; HISTONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; MIFEPRISTONE; NITRIC OXIDE SYNTHASE; NITRITE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA ANTAGONIST; PIRINIXIC ACID; PROTEIN INHIBITOR; QUERCETIN; RESVERATROL; RHAPONTIN; TAMOXIFEN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

EID: 4544310412     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00110.2004     Document Type: Article
Times cited : (346)

References (48)
  • 2
    • 0033761182 scopus 로고    scopus 로고
    • Inhibitory activity of stilbenes from medicinal plants on the expression of cell adhesion molecules on THP1 cells
    • Ahn KS, Kim JH, Oh SR, Ryu SY, and Lee HK. Inhibitory activity of stilbenes from medicinal plants on the expression of cell adhesion molecules on THP1 cells. Planta Med 66: 641-644, 2000.
    • (2000) Planta Med , vol.66 , pp. 641-644
    • Ahn, K.S.1    Kim, J.H.2    Oh, S.R.3    Ryu, S.Y.4    Lee, H.K.5
  • 3
    • 0032549174 scopus 로고    scopus 로고
    • IκBα degradation and nuclear factor-κB DNA binding are insufficient for interleukin-1β- and tumor necrosis factor-α-induced κB-dependent transcription. Requirement for an additional activation pathway
    • Bergmann M, Hart L, Lindsay M, Barnes PJ, and Newton R. IκBα degradation and nuclear factor-κB DNA binding are insufficient for interleukin-1β- and tumor necrosis factor-α-induced κB-dependent transcription. Requirement for an additional activation pathway. J Biol Chem 273: 6607-6610, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 6607-6610
    • Bergmann, M.1    Hart, L.2    Lindsay, M.3    Barnes, P.J.4    Newton, R.5
  • 4
    • 0031183766 scopus 로고    scopus 로고
    • The role of nuclear factor-κB in cytokine gene regulation
    • Blackwell TS and Christman JW. The role of nuclear factor-κB in cytokine gene regulation. Am J Respir Cell Mol Biol 17: 3-9, 1997.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 3-9
    • Blackwell, T.S.1    Christman, J.W.2
  • 6
    • 0032861582 scopus 로고    scopus 로고
    • Resveratrol has antagonist activity on the aryl hydrocarbon receptor: Implications for prevention of dioxin toxicity
    • Casper RF, Quesne M, Rogers IM, Shirota T, Jolivet A, Milgrom E, and Savouret JF. Resveratrol has antagonist activity on the aryl hydrocarbon receptor: implications for prevention of dioxin toxicity. J Histochem Cytochem 56: 784-790, 1999.
    • (1999) J Histochem Cytochem , vol.56 , pp. 784-790
    • Casper, R.F.1    Quesne, M.2    Rogers, I.M.3    Shirota, T.4    Jolivet, A.5    Milgrom, E.6    Savouret, J.F.7
  • 8
    • 0032862195 scopus 로고    scopus 로고
    • Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol
    • Ciolino HP and Yeh GC. Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol. J Histochem Cytochem 56: 760-767, 1999.
    • (1999) J Histochem Cytochem , vol.56 , pp. 760-767
    • Ciolino, H.P.1    Yeh, G.C.2
  • 9
    • 0031592217 scopus 로고    scopus 로고
    • Tamoxifen inhibits the release of arachidonic acid stimulated by thapsigargin in estrogen receptor-negative A 549 cells
    • Croxtall JD, Choudhury Q, White JO, and Flower RJ. Tamoxifen inhibits the release of arachidonic acid stimulated by thapsigargin in estrogen receptor-negative A549 cells. Biochim Biophys Acta 1349: 275-284, 1997.
    • (1997) Biochim Biophys Acta , vol.1349 , pp. 275-284
    • Croxtall, J.D.1    Choudhury, Q.2    White, J.O.3    Flower, R.J.4
  • 11
    • 0032696013 scopus 로고    scopus 로고
    • Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease
    • Culpitt SV, Maziak W, Loukidis S, Nightingale JA, Matthews JL, and Barnes PJ. Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160: 1635-1639, 1999.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1635-1639
    • Culpitt, S.V.1    Maziak, W.2    Loukidis, S.3    Nightingale, J.A.4    Matthews, J.L.5    Barnes, P.J.6
  • 13
    • 0037216753 scopus 로고    scopus 로고
    • Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease
    • Culpitt SV, Rogers DF, Shah P, De Matos C, Russell RE, Donnelly LE, and Barnes PJ. Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 167: 24-31, 2003.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 24-31
    • Culpitt, S.V.1    Rogers, D.F.2    Shah, P.3    De Matos, C.4    Russell, R.E.5    Donnelly, L.E.6    Barnes, P.J.7
  • 14
    • 0030666110 scopus 로고    scopus 로고
    • 4 production by N-acetylcysteine: Role of hydrogen peroxide
    • 4 production by N-acetylcysteine: role of hydrogen peroxide. Br J Pharmacol 122: 758-764, 1997.
    • (1997) Br J Pharmacol , vol.122 , pp. 758-764
    • Dent, G.1    Rabe, K.F.2    Magnussen, H.3
  • 15
    • 0035089495 scopus 로고    scopus 로고
    • Expression of heme oxygenase in human airway epithelial cells
    • Donnelly LE and Barnes PJ. Expression of heme oxygenase in human airway epithelial cells. Am J Respir Cell Mol Biol 24: 295-303, 2001.
    • (2001) Am J Respir Cell Mol Biol , vol.24 , pp. 295-303
    • Donnelly, L.E.1    Barnes, P.J.2
  • 16
    • 0036006808 scopus 로고    scopus 로고
    • Expression and regulation of inducible nitric oxide synthase from human primary airway epithelial cells
    • Donnelly LE and Barnes PJ. Expression and regulation of inducible nitric oxide synthase from human primary airway epithelial cells. Am J Respir Cell Mol Biol 26: 144-151, 2002.
    • (2002) Am J Respir Cell Mol Biol , vol.26 , pp. 144-151
    • Donnelly, L.E.1    Barnes, P.J.2
  • 17
    • 0033036639 scopus 로고    scopus 로고
    • Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation
    • ElAttar TM and Viril AS. Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation. Anticancer Drugs 10: 187-193, 1999.
    • (1999) Anticancer Drugs , vol.10 , pp. 187-193
    • ElAttar, T.M.1    Viril, A.S.2
  • 18
    • 0038309561 scopus 로고    scopus 로고
    • Resveratrol activates adenylyl-cyclase in human breast cancer cells: A novel, estrogen receptor-independent cytostatic mechanism
    • El Mowafy AM and Alkhalaf M. Resveratrol activates adenylyl-cyclase in human breast cancer cells: a novel, estrogen receptor-independent cytostatic mechanism. Carcinogenesis 24: 869-873, 2003.
    • (2003) Carcinogenesis , vol.24 , pp. 869-873
    • El Mowafy, A.M.1    Alkhalaf, M.2
  • 19
    • 0034645693 scopus 로고    scopus 로고
    • Biological effects of resveratrol
    • Fremont L. Biological effects of resveratrol. Life Sci 66: 663-673, 2000.
    • (2000) Life Sci , vol.66 , pp. 663-673
    • Fremont, L.1
  • 20
    • 0031444281 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor
    • Gehm BD, McAndrews JM, Chien PY, and Jameson JL. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor. Proc Natl Acad Sci USA 94: 14138-14143, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 14138-14143
    • Gehm, B.D.1    McAndrews, J.M.2    Chien, P.Y.3    Jameson, J.L.4
  • 21
    • 0033826684 scopus 로고    scopus 로고
    • The health benefits of wine
    • German JB and Walzem RL. The health benefits of wine. Annu Rev Nutr 20: 561-593, 2000.
    • (2000) Annu Rev Nutr , vol.20 , pp. 561-593
    • German, J.B.1    Walzem, R.L.2
  • 22
    • 0000750341 scopus 로고
    • Direct gas chromatographic-mass spectrometric method to assay cis-resveratrol in wines: Preliminary survey of its concentration in commercial wines
    • Goldberg DM, Karumanchiri A, Ng E, Yan J, Diamandis EP, and Soleas GJ. Direct gas chromatographic-mass spectrometric method to assay cis-resveratrol in wines: preliminary survey of its concentration in commercial wines. J Agric Food Chem 43: 1245-1250, 1995.
    • (1995) J Agric Food Chem , vol.43 , pp. 1245-1250
    • Goldberg, D.M.1    Karumanchiri, A.2    Ng, E.3    Yan, J.4    Diamandis, E.P.5    Soleas, G.J.6
  • 23
    • 0027532674 scopus 로고
    • 5 receptors expressed in stable cAMP-responsive luciferase reporter cell lines
    • 5 receptors expressed in stable cAMP-responsive luciferase reporter cell lines. J Recept Res 13: 79-94, 1993.
    • (1993) J Recept Res , vol.13 , pp. 79-94
    • Himmler, A.1    Stratowa, C.2    Czernilofsky, A.P.3
  • 24
    • 0034234254 scopus 로고    scopus 로고
    • Chemopreventive properties of transresveratrol are associated with inhibition of activation of the IκB kinase
    • Holmes MM and Baldwin ASJ. Chemopreventive properties of transresveratrol are associated with inhibition of activation of the IκB kinase. Cancer Res 60: 3477-3483, 2000.
    • (2000) Cancer Res , vol.60 , pp. 3477-3483
    • Holmes, M.M.1    Baldwin, A.S.J.2
  • 25
    • 0030936236 scopus 로고    scopus 로고
    • Inhibition of IL-8 gene expression in Caco-2 cells by compounds which induce histone hyperacetylation
    • Huang N, Katz JP, Martin DR, and Wu GD. Inhibition of IL-8 gene expression in Caco-2 cells by compounds which induce histone hyperacetylation. Cytokine 9: 27-36, 1997.
    • (1997) Cytokine , vol.9 , pp. 27-36
    • Huang, N.1    Katz, J.P.2    Martin, D.R.3    Wu, G.D.4
  • 26
    • 1642268085 scopus 로고    scopus 로고
    • Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor-α in mice
    • Inoue H, Jiang XF, Katayama T, Osada S, Umesono K, and Namura S. Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor-α in mice. Neurosci Lett 352: 203-206, 2003.
    • (2003) Neurosci Lett , vol.352 , pp. 203-206
    • Inoue, H.1    Jiang, X.F.2    Katayama, T.3    Osada, S.4    Umesono, K.5    Namura, S.6
  • 27
    • 0033821409 scopus 로고    scopus 로고
    • Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1β-induced histone H 4 acetylation on lysines 8 and 12
    • Ito K, Barnes PJ, and Adcock IM. Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1β-induced histone H4 acetylation on lysines 8 and 12. Mol Cell Biol 20: 6891-6903, 2000.
    • (2000) Mol Cell Biol , vol.20 , pp. 6891-6903
    • Ito, K.1    Barnes, P.J.2    Adcock, I.M.3
  • 29
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270: 16483-16486, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 16483-16486
    • Karin, M.1
  • 30
    • 0031969571 scopus 로고    scopus 로고
    • Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells
    • Kawada N, Seki S, Inoue M, and Kuroki T. Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells. Hepatology 27: 1265-1274, 1998.
    • (1998) Hepatology , vol.27 , pp. 1265-1274
    • Kawada, N.1    Seki, S.2    Inoue, M.3    Kuroki, T.4
  • 31
  • 32
    • 0032898142 scopus 로고    scopus 로고
    • Pharmacological characterization of glucocorticoid receptors in primary human bronchial epithelial cells
    • LeVan TD, Babin EA, Yamamura HI, and Bloom JW. Pharmacological characterization of glucocorticoid receptors in primary human bronchial epithelial cells. Biochem Pharmacol 57: 1003-1009, 1999.
    • (1999) Biochem Pharmacol , vol.57 , pp. 1003-1009
    • LeVan, T.D.1    Babin, E.A.2    Yamamura, H.I.3    Bloom, J.W.4
  • 33
    • 0032913414 scopus 로고    scopus 로고
    • Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells
    • Lu R and Serrero G. Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells. J Cell Physiol 179: 297-304, 1999.
    • (1999) J Cell Physiol , vol.179 , pp. 297-304
    • Lu, R.1    Serrero, G.2
  • 34
    • 0034660659 scopus 로고    scopus 로고
    • Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-κB, activator protein-1, and apoptosis: Potential role of reactive oxygen intermediates and lipid peroxidation
    • Manna SK, Mukhopadhyay A, and Aggarwal BB. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-κB, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation. J Immunol 164: 6509-6519, 2000.
    • (2000) J Immunol , vol.164 , pp. 6509-6519
    • Manna, S.K.1    Mukhopadhyay, A.2    Aggarwal, B.B.3
  • 35
    • 0033952265 scopus 로고    scopus 로고
    • Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production
    • Martinez J and Moreno JJ. Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production. Biochem Pharmacol 59: 865-870, 2000.
    • (2000) Biochem Pharmacol , vol.59 , pp. 865-870
    • Martinez, J.1    Moreno, J.J.2
  • 36
    • 0034696073 scopus 로고    scopus 로고
    • Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages
    • Matsuda H, Kageura T, Morikawa T, Toguchida I, Harima S, and Yoshikawa M. Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages. Bioorg Med Chem Lett 10: 323-327, 2000.
    • (2000) Bioorg Med Chem Lett , vol.10 , pp. 323-327
    • Matsuda, H.1    Kageura, T.2    Morikawa, T.3    Toguchida, I.4    Harima, S.5    Yoshikawa, M.6
  • 38
    • 0034130914 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoid action: What is important?
    • Newton R. Molecular mechanisms of glucocorticoid action: what is important? Thorax 55: 603-613, 2000.
    • (2000) Thorax , vol.55 , pp. 603-613
    • Newton, R.1
  • 39
    • 0031559584 scopus 로고    scopus 로고
    • Evidence for involvement of NF-κB in the transcriptional control of COX-2 gene expression by IL-1β
    • Newton R, Kuitert LM, Bergmann M, Adcock IM, and Barnes PJ. Evidence for involvement of NF-κB in the transcriptional control of COX-2 gene expression by IL-1β. Biochem Biophys Res Commun 237: 28-32, 1997.
    • (1997) Biochem Biophys Res Commun , vol.237 , pp. 28-32
    • Newton, R.1    Kuitert, L.M.2    Bergmann, M.3    Adcock, I.M.4    Barnes, P.J.5
  • 41
    • 0033610923 scopus 로고    scopus 로고
    • 2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA
    • 2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA. J Biol Chem 273: 32312-32321, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 32312-32321
    • Newton, R.1    Seybold, J.2    Kuitert, L.M.3    Bergmann, M.4    Barnes, P.J.5
  • 43
    • 0037082355 scopus 로고    scopus 로고
    • The "French paradox" and beyond: Neuroprotective effects of polyphenols(1,2)
    • Sun AY, Simonyi A, and Sun GY. The "French paradox" and beyond: neuroprotective effects of polyphenols(1,2). Free Radic Biol Med 32: 314-318, 2002.
    • (2002) Free Radic Biol Med , vol.32 , pp. 314-318
    • Sun, A.Y.1    Simonyi, A.2    Sun, G.Y.3
  • 44
    • 2542445157 scopus 로고    scopus 로고
    • Resveratrol is a peroxidase-mediated inactivator of COX-1 but not COX-2: A mechanistic approach to the design of COX-1-selective agents
    • Szewczuk LM, Forti L, Stivala LA, and Penning TM. Resveratrol is a peroxidase-mediated inactivator of COX-1 but not COX-2: a mechanistic approach to the design of COX-1-selective agents. J Biol Chem 279: 22727-22737, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 22727-22737
    • Szewczuk, L.M.1    Forti, L.2    Stivala, L.A.3    Penning, T.M.4
  • 45
    • 0033023541 scopus 로고    scopus 로고
    • Suppression of nitric oxide synthase and the down-regulation of the activation of NFκB in macrophages by resveratrol
    • Tsai SH, Lin-Shiau SY, and Lin JK. Suppression of nitric oxide synthase and the down-regulation of the activation of NFκB in macrophages by resveratrol. Br J Pharmacol 126: 673-680, 1999.
    • (1999) Br J Pharmacol , vol.126 , pp. 673-680
    • Tsai, S.H.1    Lin-Shiau, S.Y.2    Lin, J.K.3
  • 47
    • 0033561579 scopus 로고    scopus 로고
    • Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages
    • Wadsworth TL and Koop DR. Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages. Biochem Pharmacol 57: 941-949, 1999.
    • (1999) Biochem Pharmacol , vol.57 , pp. 941-949
    • Wadsworth, T.L.1    Koop, D.R.2


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