-
1
-
-
2442586535
-
Copper depletion down-regulates expression of Alzheimer's disease Amyloid-β precursor protein gene
-
Bellingham S. A., Lahiri D. K., Maloney B., La Fontaine S., Multhaup G. and Camakaris J. (2004) Copper depletion down-regulates expression of Alzheimer's disease Amyloid-β precursor protein gene. J. Biol. Chem. 279, 20378-20386.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20378-20386
-
-
Bellingham, S.A.1
Lahiri, D.K.2
Maloney, B.3
La Fontaine, S.4
Multhaup, G.5
Camakaris, J.6
-
2
-
-
0031587441
-
APP gene promoter constructs are preferentially expressed in the CNS and testis of transgenic mice
-
Fox N. W., Johnstone E. M., Ward K. E., Schrementi J. and Little S. P. (1997) APP gene promoter constructs are preferentially expressed in the CNS and testis of transgenic mice. Biochem. Biophys. Res. Commun. 240, 759-762.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.240
, pp. 759-762
-
-
Fox, N.W.1
Johnstone, E.M.2
Ward, K.E.3
Schrementi, J.4
Little, S.P.5
-
3
-
-
0036959504
-
Regulation of promoter activity of the APP gene by cytokines and growth factors: Implications in Alzheimer's disease
-
Ge Y.-W. and Lahiri D. K. (2002) Regulation of promoter activity of the APP gene by cytokines and growth factors: implications in Alzheimer's disease. Ann. NY Acad. Sci. 973, 463-467.
-
(2002)
Ann. NY Acad. Sci.
, vol.973
, pp. 463-467
-
-
Ge, Y.-W.1
Lahiri, D.K.2
-
4
-
-
0242496340
-
Determinants of GATA-1 binding to DNA: The role of non-finger residues
-
Ghirlando R. and Trainor C. D. (2003) Determinants of GATA-1 binding to DNA: the role of non-finger residues. J. Biol. Chem. 278, 45620-45628.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 45620-45628
-
-
Ghirlando, R.1
Trainor, C.D.2
-
5
-
-
0033368280
-
Increased vulnerability of neuronal cell lines to sodium nitroprusside-mediated toxicity is caused by the decreased level of nitric oxide metabolites
-
Ghosh C. and Lahiri D. K. (1999) Increased vulnerability of neuronal cell lines to sodium nitroprusside-mediated toxicity is caused by the decreased level of nitric oxide metabolites. J. Mol. Neurosci. 13, 77-92.
-
(1999)
J. Mol. Neurosci.
, vol.13
, pp. 77-92
-
-
Ghosh, C.1
Lahiri, D.K.2
-
6
-
-
0033755065
-
Efficient DNA transfection in neuronal and astrocytic cell lines
-
Ghosh C., Song W. and Lahiri D. K. (2000) Efficient DNA transfection in neuronal and astrocytic cell lines. Mol. Biol. Report 27, 113-121.
-
(2000)
Mol. Biol. Report
, vol.27
, pp. 113-121
-
-
Ghosh, C.1
Song, W.2
Lahiri, D.K.3
-
7
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J. and Selkoe D. J. (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
8
-
-
0025295476
-
Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease
-
Johnson S. A., McNeill T., Cordell B. and Finch C. E. (1990) Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease. Science 248, 854-857.
-
(1990)
Science
, vol.248
, pp. 854-857
-
-
Johnson, S.A.1
McNeill, T.2
Cordell, B.3
Finch, C.E.4
-
9
-
-
0028263141
-
Temporal and spatial changes in GATA transcription factor expression are coincident with development of the chicken optic tectum
-
Kornhauser J. M., Leonard M. W., Yamamoto M., LaVail J. H., Mayo K. E. and Engel J. D. (1994) Temporal and spatial changes in GATA transcription factor expression are coincident with development of the chicken optic tectum. Brain Res. Mol. Brain Res. 23, 100-110.
-
(1994)
Brain Res. Mol. Brain Res.
, vol.23
, pp. 100-110
-
-
Kornhauser, J.M.1
Leonard, M.W.2
Yamamoto, M.3
LaVail, J.H.4
Mayo, K.E.5
Engel, J.D.6
-
10
-
-
0029091767
-
The upstream stimulatory factor functionally interacts with the Alzheimer amyloid β-protein precursor gene
-
Kovacs D. M., Wasco W., Witherby J., Felsenstein K. M., Brunei F., Roeder R. G. and Tanzi R. E. (1995) The upstream stimulatory factor functionally interacts with the Alzheimer amyloid β-protein precursor gene. Hum. Mol. Genet. 4, 1527-1533.
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 1527-1533
-
-
Kovacs, D.M.1
Wasco, W.2
Witherby, J.3
Felsenstein, K.M.4
Brunei, F.5
Roeder, R.G.6
Tanzi, R.E.7
-
11
-
-
0024542108
-
Characterization of the 5′-end region and the first two exons of the β-protein precursor gene
-
La Fauci G., Lahiri D. K., Salton S. R. and Robakis N. K. (1989) Characterization of the 5′-end region and the first two exons of the β-protein precursor gene. Biochem. Biophys. Res. Commun. 159, 297-304.
-
(1989)
Biochem. Biophys. Res. Commun.
, vol.159
, pp. 297-304
-
-
La Fauci, G.1
Lahiri, D.K.2
Salton, S.R.3
Robakis, N.K.4
-
12
-
-
0032527764
-
An region upstream of the gene promoter for the β-amyloid precursor protein interacts with proteins from nuclear extracts of the human brain and PC12 cells
-
Lahiri D. K. (1998) An region upstream of the gene promoter for the β-amyloid precursor protein interacts with proteins from nuclear extracts of the human brain and PC12 cells. Brain Res. Mol. Brain Res. 58, 112-122.
-
(1998)
Brain Res. Mol. Brain Res.
, vol.58
, pp. 112-122
-
-
Lahiri, D.K.1
-
13
-
-
0029114162
-
Promoter activity of the gene encoding the β-amyloid precursor protein is upregulated by growth factors, phorbol ester, retinoic acid and interleukin-1
-
Lahiri D. K. and Nall C. (1995) Promoter activity of the gene encoding the β-amyloid precursor protein is upregulated by growth factors, phorbol ester, retinoic acid and interleukin-1. Brain Res. Mol. Brain Res. 32, 233-240.
-
(1995)
Brain Res. Mol. Brain Res.
, vol.32
, pp. 233-240
-
-
Lahiri, D.K.1
Nall, C.2
-
14
-
-
0025967258
-
The promoter activity of the gene encoding Alzheimer β-amyloid precursor protein (APP) is regulated by two blocks of upstream sequences
-
Lahiri D. K. and Robakis N. K. (1991) The promoter activity of the gene encoding Alzheimer β-amyloid precursor protein (APP) is regulated by two blocks of upstream sequences. Brain Res. Mol. Brain Res. 9, 253-257.
-
(1991)
Brain Res. Mol. Brain Res.
, vol.9
, pp. 253-257
-
-
Lahiri, D.K.1
Robakis, N.K.2
-
15
-
-
0028197477
-
Tacrine alters the secretion of the β-amyloid precursor protein in cell lines
-
Lahiri D. K., Lewis S. and Farlow M. R. (1994) Tacrine alters the secretion of the β-amyloid precursor protein in cell lines. J. Neurosci. Res. 37, 777-787.
-
(1994)
J. Neurosci. Res.
, vol.37
, pp. 777-787
-
-
Lahiri, D.K.1
Lewis, S.2
Farlow, M.R.3
-
16
-
-
0033050955
-
Promoter activity of the β-amyloid precursor protein gene is negatively modulated by an upstream regulatory element
-
Lahiri D. K., Nall C. and Ge Y. W. (1999) Promoter activity of the β-amyloid precursor protein gene is negatively modulated by an upstream regulatory element. Brain Res. Mol. Brain Res. 71, 32-41.
-
(1999)
Brain Res. Mol. Brain Res.
, vol.71
, pp. 32-41
-
-
Lahiri, D.K.1
Nall, C.2
Ge, Y.W.3
-
17
-
-
0034608110
-
Analysis of the 5′-flanking region of the β-amyloid precursor protein gene that contributes to increased promoter activity in differentiated neuronal cells
-
Lahiri D. K., Song W. and Ge Y. W. (2000) Analysis of the 5′-flanking region of the β-amyloid precursor protein gene that contributes to increased promoter activity in differentiated neuronal cells. Brain Res. Mol. Brain Res. 77, 185-198.
-
(2000)
Brain Res. Mol. Brain Res.
, vol.77
, pp. 185-198
-
-
Lahiri, D.K.1
Song, W.2
Ge, Y.W.3
-
18
-
-
0037315878
-
A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease
-
Lahiri D. K., Farlow M. R., Sambamurti K., Greig N. H., Giacobini E. and Schneider L. S. (2003a) A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease. Curr. Drug Targets 4, 97-112.
-
(2003)
Curr. Drug Targets
, vol.4
, pp. 97-112
-
-
Lahiri, D.K.1
Farlow, M.R.2
Sambamurti, K.3
Greig, N.H.4
Giacobini, E.5
Schneider, L.S.6
-
19
-
-
0038705106
-
Role of cytokines in the gene expression of amyloid β-protein precursor: Identification of a 5′-UTR-binding nuclear factor and its implications in Alzheimer's disease
-
Lahiri D. K., Chen D., Vivien D., Ge Y. W., Greig N. H. and Rogers J. T. (2003b) Role of cytokines in the gene expression of amyloid β-protein precursor: Identification of a 5′-UTR-binding nuclear factor and its implications in Alzheimer's disease. J. Alzheimers Dis. 5, 81-90.
-
(2003)
J. Alzheimers Dis.
, vol.5
, pp. 81-90
-
-
Lahiri, D.K.1
Chen, D.2
Vivien, D.3
Ge, Y.W.4
Greig, N.H.5
Rogers, J.T.6
-
20
-
-
15044338559
-
Functional characterization of APP regulatory elements: Rationale for the identification of genetic polymorphism
-
in press
-
Lahiri D. K. (2004) Functional characterization of APP regulatory elements: rationale for the identification of genetic polymorphism. Ann. NY Acad. Sci. in press.
-
(2004)
Ann. NY Acad. Sci.
-
-
Lahiri, D.K.1
-
21
-
-
0029996717
-
GATA factors are essential for activity of the neuron-specific enhancer of the gonadotropin-releasing hormone gene
-
Lawson M. A., Whyte D. B. and Mellon P. L. (1996) GATA factors are essential for activity of the neuron-specific enhancer of the gonadotropin-releasing hormone gene. Mol. Cell. Biol. 16, 3596-3605.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3596-3605
-
-
Lawson, M.A.1
Whyte, D.B.2
Mellon, P.L.3
-
22
-
-
0027231112
-
DNA-binding specificity of GATA family transcription factors
-
Merika M. and Orkin S. H. (1993) DNA-binding specificity of GATA family transcription factors. Mol. Cell. Biol. 13, 3999-4010.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 3999-4010
-
-
Merika, M.1
Orkin, S.H.2
-
23
-
-
0024093904
-
Expression of the Alzheimer amyloid precursor gene transcripts in the human brain
-
Neve R. L., Finch E. A. and Dawes L. R. (1988) Expression of the Alzheimer amyloid precursor gene transcripts in the human brain. Neuron 1, 669-677.
-
(1988)
Neuron
, vol.1
, pp. 669-677
-
-
Neve, R.L.1
Finch, E.A.2
Dawes, L.R.3
-
24
-
-
0028971143
-
MatInd and Matlnspector: New fast and versatile tools for detection of consensus matches in nucleotide sequence data
-
Quandt K., Frech K., Karas H., Wingender E. and Werner T. (1995) MatInd and Matlnspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 23, 4878-884.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 4878-4884
-
-
Quandt, K.1
Frech, K.2
Karas, H.3
Wingender, E.4
Werner, T.5
-
25
-
-
0026806977
-
The amyloid beta-protein precursor promoter. A region essential for transcriptional activity contains a nuclear factor binding domain
-
Quitschke W. W. and Goldgaber D. (1992) The amyloid beta-protein precursor promoter. A region essential for transcriptional activity contains a nuclear factor binding domain. J. Biol. Chem. 267, 17362-17368.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17362-17368
-
-
Quitschke, W.W.1
Goldgaber, D.2
-
26
-
-
0031003537
-
Additive effects of basic fibroblast growth factor and phorbol ester on γ-amyloid precursor protein expression and secretion
-
Ringheim G. E., Aschmies S. and Petko W. (1997) Additive effects of basic fibroblast growth factor and phorbol ester on γ-amyloid precursor protein expression and secretion. Neurochem. Int. 30, 475-481.
-
(1997)
Neurochem. Int.
, vol.30
, pp. 475-481
-
-
Ringheim, G.E.1
Aschmies, S.2
Petko, W.3
-
27
-
-
0024075097
-
The promoter of Alzheimer's disease amyloid A4 precursor gene
-
Salbaum J. M., Weidemann A., Lemaire H. G., Masters C. L. & Beyreuther K. (1988) The promoter of Alzheimer's disease amyloid A4 precursor gene. EMBO J. 7, 2807-2813.
-
(1988)
EMBO J.
, vol.7
, pp. 2807-2813
-
-
Salbaum, J.M.1
Weidemann, A.2
Lemaire, H.G.3
Masters, C.L.4
Beyreuther, K.5
-
28
-
-
16044373524
-
Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner D., Eckman C., Jensen M. et al. (1996) Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 2, 864-870.
-
(1996)
Nat. Med.
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
-
29
-
-
0003409775
-
-
Technical Reports of the Computational Biology and Informatics Laboratory, School of Medicine, University of Pennsylvania. University of Pennsylvania, Philadelphia, PA
-
Schug J. and Overton G. C. (1998) TESS: Transcription Element Search Software on the WWW, in Technical Reports of the Computational Biology and Informatics Laboratory, School of Medicine, University of Pennsylvania, pp. 1-10. University of Pennsylvania, Philadelphia, PA.
-
(1998)
TESS: Transcription Element Search Software on the WWW
, pp. 1-10
-
-
Schug, J.1
Overton, G.C.2
-
30
-
-
0031243561
-
Melatonin alters the metabolism of the β-amyloid precursor protein in the neuroendocrine cell line PC12
-
Song W. and Lahiri D. K. (1997) Melatonin alters the metabolism of the β-amyloid precursor protein in the neuroendocrine cell line PC12. J. Mol. Neurosci. 9, 75-92.
-
(1997)
J. Mol. Neurosci.
, vol.9
, pp. 75-92
-
-
Song, W.1
Lahiri, D.K.2
-
31
-
-
0032517141
-
Molecular cloning of the promoter of the gene encoding the Rhesus monkey β-amyloid precursor protein: Structural characterization and a comparative study with other species
-
Song W. and Lahiri D. K. (1998a) Molecular cloning of the promoter of the gene encoding the Rhesus monkey β-amyloid precursor protein: structural characterization and a comparative study with other species. Gene 217, 151-164.
-
(1998)
Gene
, vol.217
, pp. 151-164
-
-
Song, W.1
Lahiri, D.K.2
-
32
-
-
0032517094
-
Functional identification of the promoter of the gene encoding the Rhesus monkey β-amyloid precursor protein
-
Song W. and Lahiri D. K. (1998b) Functional identification of the promoter of the gene encoding the Rhesus monkey β-amyloid precursor protein. Gene 217, 165-176.
-
(1998)
Gene
, vol.217
, pp. 165-176
-
-
Song, W.1
Lahiri, D.K.2
-
33
-
-
0027425601
-
A GATA family transcription factor is expressed along the embryonic dorsoventral axis in Drosophila melanogaster
-
Winick J., Abel T., Leonard M. W., Michelson A. M., Chardon-Loriaux I., Holmgren R. A., Maniatis T. and Engel J. D. (1993) A GATA family transcription factor is expressed along the embryonic dorsoventral axis in Drosophila melanogaster. Development 119, 1055-1065.
-
(1993)
Development
, vol.119
, pp. 1055-1065
-
-
Winick, J.1
Abel, T.2
Leonard, M.W.3
Michelson, A.M.4
Chardon-Loriaux, I.5
Holmgren, R.A.6
Maniatis, T.7
Engel, J.D.8
-
34
-
-
0033829599
-
GATA-2 is required for the generation of V2 interneurons
-
Zhou Y., Yamamoto M. and Engel J. D. (2000) GATA-2 is required for the generation of V2 interneurons. Development 127, 3829-3838.
-
(2000)
Development
, vol.127
, pp. 3829-3838
-
-
Zhou, Y.1
Yamamoto, M.2
Engel, J.D.3
|