Thiopurine methyltransferase pharmacogenetics: Human gene cloning and characterization of a common polymorphism

DNA and Cell Biology

Volumn 15, Issue 1, 1996, Pages 17-30

  Szumlanski, Carol ^a   Otterness, Diane ^a   Her, Chengtao ^a   Lee, Daniel ^a   Brandriff, Brigitte ^b   Kelsell, David ^c   Spurr, Nigel ^c   Lennard, Lynne ^d   Wieben, Eric ^e   Weinshilboum, Richard ^a  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

^b LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

^e MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE;

ARTICLE; CLINICAL ARTICLE; DRUG EFFICACY; DRUG RESPONSE; ENZYME ACTIVITY; ENZYME REGULATION; GENETIC POLYMORPHISM; HUMAN; MOLECULAR CLONING; PRIORITY JOURNAL;

EID: 0030048791     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.1996.15.17     Document Type: Article

References (14)

1. AKSOY, S., KLENER, J., and WEINSHILBOUM, R.M. (1993). Catechol O-methyltransferase pharmacogenetics: Photoaffinity labeling and western blot analysis of human liver samples. Pharmacogenetics 3, 116-122.
2. BARNES, W.M. (1994). PCR amplification of up to 35 kb DNA with high fidelity and high yield from lambda bacteriophage templates. Proc. Natl. Acad. Sci. USA 91, 2216-2220.
3. BRADFORD, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
4. BRIGGS, M.R., KADONAGA, J.T., BELL, S.P., and TJIAN, R. (1986). Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. Science 234, 47-52.
5. CHRISTY, B., and NATHANS, D. (1989). DNA binding site of the growth factor-inducible protein Zif268. Proc. Natl. Acad. Sci. USA 86, 8737-8741.
6. DEVEREUX, J., HAEBERLI, P., and SMITHIES, O. (1984). A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12, 387-395.
7. DRWINGA, H.L., TOJI, L.H., KIM, C.H., GREENE, A.E., and MULIVOR, R.A. (1993). NIGMS Human/Rodent Cell Hybrid Mapping Panels 1 and 2. Genomics 16, 311-314.
8. EVANS, W.E., HORNER, M., CHU, Y.Q., KALWINSKY, D., and ROBERTS, W.M. (1991). Altered mercaptopurine metabolism, toxic effects and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphoblastic leukemia. J. Pediatr. 119, 985-989.
9. FOLDES, A., and MEEK, J.L. (1973). Rat brain phenolsulfotrans-ferase - partial purification and some properties. Biochim. Biophys. Acta 327, 365-374.
10. FROHMAN, M.A., DUSH, M.K., and MARTIN, G.R. (1988). Rapid production of full-length cDNAs from rare transcripts: amplification using single gene-specific oligonucleotide primers. Proc. Natl. Acad. Sci. USA 85, 8998-9002.
11. GHOSH, D. (1990). A relational database of transcription factors. Nucleic Acids Res. 18, 1749-1756.
12. HER, C., and WEINSHILBOUM, R.M. (1995). Rapid restriction mapping by use of long PCR. BioTechniques 19, 530-532.
13. HER, C., AKSOY, I.A., KIMURA, S., BRANDRIFF, B.F., WASMUTH, J.J., and WEINSHILBOUM, R.M. (1995). Human estrogen sulfotransferase gene (STE): Cloning, structure and chromosomal localization. Genomics 29, 16-23.
14. HERNÁNDEZ, J.S., VAN LOON, J.A., OTTERNESS, D.M., and WEINSHILBOUM, R.M. (1990). Mouse thiopurine methyltransferase pharmacogenetics: correlation of immunoreactive protein and enzymatic activity. J. Pharmacol. Exp. Ther. 252, 568-573.