Unravelling the functional genomics of the human CYP2D6 gene locus

Pharmacogenetics

Volumn 11, Issue 7, 2001, Pages 553-554

  Ingelman Sundberg, M ^a   Evans, W E ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2D6; SPARTEINE;

DRUG METABOLISM; EDITORIAL; ENZYME POLYMORPHISM; GENE EXPRESSION; GENE FUNCTION; GENE LOCUS; GENOTYPE; HUMAN; PHENOTYPE; PRIORITY JOURNAL;

CYTOCHROME P-450 CYP2D6; GENETIC MARKERS; GENOMICS; HUMANS;

EID: 0034796765     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200110000-00002     Document Type: Editorial

References (5)

1. Pharmacogenomics: Translating functional genomics into rational therapeutics
2. Poymorphic human cytochrome P450 enzymes: An opportunity for individualized drug treatment
3. Evidence for altered catalytic properties of the cytochrome P-450 involved in sparteine oxidation in poor metabolizers
4. Elucidation of the genetics basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6
5. Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6