Retinoic acid is detected at relatively high levels in the CNS of adult rats

American Journal of Physiology - Endocrinology and Metabolism

Volumn 282, Issue 3 45-3, 2002, Pages

  Werner, Elizabeth A ^a   Deluca, Hector F ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

All trans retinoic acid; All trans retinol; Central nervous system; Vitamin A deficiency

Indexed keywords

RETINOIC ACID; RETINOL;

ANIMAL TISSUE; ARTICLE; BRAIN CIRCULATION; CELL DIFFERENTIATION; CELL GROWTH; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; MALE; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; RAT; SPINAL CORD; TRANSPORT KINETICS;

EID: 0036087066     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00280.2001     Document Type: Article

References (31)

1. The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures
2. Retinoic acid receptors and retinoid X receptors: Interactions with endogenous retinoic acids
3. A rapid method of total lipid extraction and purification
4. A decade of molecular biology of retinoic acid receptors
5. Teratology of retinoids
6. Site-specific retinoic acid production in the brain of adult songbirds
7. Retinoic acid: An endogenous compound of human blood. Unequivocal demonstration of endogenous retinoic acid in normal physiological conditions
8. Adult rabbit brain synthesizes retinoic acid
9. The biological function of vitamin A acid
10. Families of retinoid dehydrogenases regulating vitamin A function
11. Retinoic acid causes an anteriorposterior transformation in the developing central nervous system
12. Impaired locomotion and dopamine signaling in retinoid receptor mutant mice
13. Plasma delivery of retinoic acid to tissues in the rat
14. Effect of vitamin A on development of the central nervous system
15. Pharmacokinetics of all-trans-retinoic acid, 13-cis-retinoic acid, and fenretinide in plasma and brain of rat
16. Reversed-phase high performance liquid chromatographic separation and electrochemical detection of retinol and its isomers
17. Localization of cellular retinol-binding protein and retinol-binding protein in cells comprising the blood-brain barrier of rat and human
18. The role of vitamin A in the development of the central nervous system
19. High levels of a retinoic acid-generating dehydrogenase in the meso-telencephalic dopamine system
20. Simultaneous determination of endogenous retinoic acid isomers and retinol in human plasma by isocratic normal-phase HPLC with ultraviolet detection
21. The distribution of intravenously-injected inulin in the fluid of the nervous system of the dog and rat
22. Separation and identification of retinoic acid photoisomers
23. All-trans-retinoic acid stimulates and maintains neurite outgrowth in nerve-growth factor-supported developing chick embryonic sympathic neurons
24. Regulation of dopaminergic pathways by retinoids: Activation of the D2 receptor promoter by members of the retinoic acid receptor-retinoid X receptor family
25. The plasma transport and metabolism of retinoic acid in the rat
26. Vitamin A and reproduction in rats
27. Metabolism of a physiological amount of all-trans-retinol in the vitamin A-deficient rat
28. Abnormal development of the inuatrial venous valve and posterior hindbrain may contribute to late fetal resorption of vitamin A-deficient rat embryos
29. Identification of the human cytochrome P450, P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans-retinoic acid metabolism
30. Defects in embryonic hindbrain development and fetal resorption resulting from vitamin A deficiency in the rat are prevented by feeding pharmacological levels of all-transretinoic acid
31. Retinoid-binding proteins in the cerebellum and choroid plexus and their relationship to regionalized retinoic acid synthesis and degradation