Inhibition of Cdc7/Dbf4 kinase activity affects specific phosphorylation sites on MCM2 in cancer cells

Journal of Cellular Biochemistry

Volumn 104, Issue 3, 2008, Pages 1075-1086

  Charych, Deborah H ^a,b   Coyne, Mazie ^a   Yabannavar, Asha ^a   Narberes, Jamie ^a   Chow, Sylvia ^a   Wallroth, Marco ^a   Shafer, Cynthia ^a   Walter, Annette O ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b FIVE PRIME THERAPEUTICS INC   (United States)

Author keywords

Cancer; Kinase; Mass spectrometry; Phosphorylation site; Target modulation

Indexed keywords

DNA POLYMERASE; MINICHROMOSOME MAINTENANCE PROTEIN 2; MINICHROMOSOME MAINTENANCE PROTEIN 4; MINICHROMOSOME MAINTENANCE PROTEIN 6; PROTEIN CDC45; PROTEIN CDC7; PROTEIN DBF4; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; SERINE;

ARTICLE; CANCER CELL; CHROMATIN; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; APOPTOSIS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CHROMATIN; COLONIC NEOPLASMS; HUMANS; LUNG NEOPLASMS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES;

EID: 45149124103     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21698     Document Type: Article

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