Shape Shifting Leads to Small-Molecule Allosteric Drug Discovery

Chemistry and Biology

Volumn 15, Issue 6, 2008, Pages 586-596

  Lawrence, Sarah H ^a   Ramirez, Ursula D ^a   Tang, Lei ^a   Fazliyez, Farit ^a   Kundrat, Lenka ^a   Markham, George D ^a   Jaffe, Eileen K ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

CHEMBIO; PROTEINS

Indexed keywords

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; DIMERIZATION; DRUG DESIGN; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SEQUENCE HOMOLOGY;

ALLOSTERIC SITE; AMINO ACID SEQUENCE; ANIMALS; DIMERIZATION; DRUG DESIGN; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 44949165598     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2008.04.012     Document Type: Article

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