Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase

Nature Structural Biology

Volumn 10, Issue 9, 2003, Pages 757-763

  Breinig, Sabine ^a   Kervinen, Jukka ^b   Stith, Linda ^a   Wasson, Andrew S ^c   Fairman, Robert ^c   Wlodawer, Alexander ^d   Zdanov, Alexander ^d   Jaffe, Eileen K ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b JOHNSON AND JOHNSON   (United States)

^c HAVERFORD COLLEGE   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROPHYLL; HEME; MAGNESIUM; PLASMID DNA; PORPHOBILINOGEN SYNTHASE; PYRROLE DERIVATIVE; TETRAPYRROLE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM; BIOSYNTHESIS; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME STRUCTURE; HUMAN; PLANT; PRIORITY JOURNAL; PROTEIN PURIFICATION; X RAY DIFFRACTION;

ALLOSTERIC SITE; ANIMALS; BINDING SITES; CHLOROPHYLL; CHO CELLS; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EDETIC ACID; GLUTATHIONE TRANSFERASE; HEME; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MAGNESIUM; MODELS, MOLECULAR; PLANTS; PORPHOBILINOGEN SYNTHASE; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PYRROLES; TETRAPYRROLES; ULTRACENTRIFUGATION;

BACTERIA (MICROORGANISMS); HOMO;

EID: 0041318843     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb963     Document Type: Article

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