Expansion of the octarepeat domain alters the misfolding pathway but not the folding pathway of the prion protein

Biochemistry

Volumn 47, Issue 23, 2008, Pages 6267-6278

  Leliveld, S Rutger ^a   Stitz, Lothar ^b   Korth, Carsten ^c  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

^b FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FOLDING PATHWAY; MISFOLDING; PRION PROTEIN (PRP);

PROTEIN FOLDING;

AMYLOID; HYBRID PROTEIN; PRION PROTEIN; PROTEIN G;

ARTICLE; BIOASSAY; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; MOUSE; MUTATION; NONHUMAN; NUCLEOTIDE REPEAT; OCTAREPEAT; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; CIRCULAR DICHROISM; KINETICS; MICE; MUTAGENESIS, INSERTIONAL; OPEN READING FRAMES; PRIONS; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PRPSC PROTEINS; RECOMBINANT PROTEINS; REPETITIVE SEQUENCES, AMINO ACID; THROMBIN;

MUS MUSCULUS;

EID: 44949123779     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi800253c     Document Type: Article

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