Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion

Journal of Neurochemistry

Volumn 104, Issue 5, 2008, Pages 1293-1308

  Biasini, Emiliano ^a   Medrano, Andrea Z ^a   Thellung, Stefano ^a,c   Chiesa, Roberto ^b   Harris, David A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

Neurodegeneration; Prion; Prion protein; Protein aggregates; Scrapie isoform of prion protein; Transgenic mice

Indexed keywords

OCTAPEPTIDE; PHOSPHOTUNGSTIC ACID; PRION PROTEIN; PRION PROTEIN ANTIBODY;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL COMPOSITION; BIOCHEMISTRY; GENE INSERTION; IMMUNOPRECIPITATION; INFECTION; MOUSE; NEUROTOXICITY; NONHUMAN; OLIGOMERIZATION; PATHOGENICITY; PRECIPITATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN STRUCTURE;

ANIMALS; BRAIN; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; MUTAGENESIS, INSERTIONAL; PEPTIDES; PRION DISEASES; PRIONS; PROTEIN FOLDING;

ANIMALIA; MUS; MUS MUSCULUS;

EID: 39749094951     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.05082.x     Document Type: Article

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