AAV delivery of mineralocorticoid receptor shRNA prevents progression of cold-induced hypertension and attenuates renal damage

Gene Therapy

Volumn 13, Issue 14, 2006, Pages 1097-1103

  Wang, X ^a   Skelley, L ^a   Cade, R ^a   Sun, Z ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Cold induced hypertension; Mineralocorticoid receptor; Renal damage; RNAi; shRNA

Indexed keywords

BUFFER; CREATININE; MINERALOCORTICOID RECEPTOR; NITROGEN; PARVOVIRUS VECTOR; PHOSPHATE; SHORT HAIRPIN RNA; SODIUM; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE MEASUREMENT; COLD; CONTROLLED STUDY; DISEASE CONTROL; DISEASE COURSE; GENE SILENCING; HYPERTENSION; IMMUNOHISTOCHEMISTRY; KIDNEY DISEASE; KIDNEY FUNCTION; KIDNEY HYPERTROPHY; KIDNEY TUBULE DISORDER; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT; RECEPTOR DOWN REGULATION; RNA INTERFERENCE; SODIUM EXCRETION; TREATMENT OUTCOME; UREA NITROGEN BLOOD LEVEL; URINARY EXCRETION; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT; WESTERN BLOTTING;

ANIMALS; AORTA; COLD; DEPENDOVIRUS; DISEASE PROGRESSION; GENE THERAPY; HYPERTENSION; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY DISEASES; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANDROGEN; RECEPTORS, GLUCOCORTICOID; RECEPTORS, MINERALOCORTICOID; RNA, SMALL INTERFERING;

ADENO-ASSOCIATED VIRUS;

EID: 33745754046     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/sj.gt.3302768     Document Type: Article

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