Endotoxin-induced proteolytic reduction in hepatic growth hormone (GH) receptor: A novel mechanism for GH insensitivity

Molecular Endocrinology

Volumn 22, Issue 6, 2008, Pages 1427-1437

  Wang, Xiangdong ^a,i   Jiang, Jing ^a   Warram, Jason ^b   Baumann, Gerhard ^d   Gan, Yujun ^c   Menon, Ram K ^e   Denson, Lee A ^f   Zinn, Kurt R ^b   Frank, Stuart J ^a,c,g,h  

^a and Clinical Center   (United States)

^b University of Alabama   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^g BIRMINGHAM VA MEDICAL CENTER   (United States)

^h UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

ⁱ SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; GROWTH HORMONE; GROWTH HORMONE BINDING PROTEIN; GROWTH HORMONE RECEPTOR; LIPOPOLYSACCHARIDE; MESSENGER RNA; METALLOPROTEINASE; MUTANT PROTEIN; STAT5 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MONITORING; BIOLUMINESCENCE; CONTROLLED STUDY; DESENSITIZATION; FEMALE; GENE EXPRESSION; HORMONE RESISTANCE; MALE; MOUSE; NON INVASIVE MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RECEPTOR GENE; REDUCTION; SIGNAL TRANSDUCTION; WILD TYPE;

ADAM PROTEINS; ANIMALS; CARRIER PROTEINS; DRUG RESISTANCE; ENDOTOXINS; FEMALE; GROWTH HORMONE; LIPOPOLYSACCHARIDES; LIVER; MALE; MICE; MICE, INBRED C3H; MICE, NUDE; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, GROWTH FACTOR; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR;

ANIMALIA; MUS;

EID: 44649168952     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2007-0561     Document Type: Article

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