메뉴 건너뛰기




Volumn 376, Issue 2, 2008, Pages 379-389

Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice

Author keywords

Coronavirus; hACE 2 transgenic mice; SARS CoV

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; PROTEIN 6; PROTEIN 7A; PROTEIN 7B; PROTEIN 8A; PROTEIN 8B; PROTEIN 9B; PROTEIN E; VIRUS PROTEIN; VIRUS RECEPTOR;

EID: 44649132470     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.03.005     Document Type: Article
Times cited : (135)

References (75)
  • 1
    • 7644242097 scopus 로고    scopus 로고
    • The nucleoprotein is required for efficient coronavirus genome replication
    • Almazan F., Galan C., and Enjuanes L. The nucleoprotein is required for efficient coronavirus genome replication. J. Virol. 78 (2004) 12683-12688
    • (2004) J. Virol. , vol.78 , pp. 12683-12688
    • Almazan, F.1    Galan, C.2    Enjuanes, L.3
  • 3
    • 34447620646 scopus 로고    scopus 로고
    • Open reading frame 8a of the human severe acute respiratory syndrome coronavirus not only promotes viral replication but also induces apoptosis
    • Chen C.Y., Ping Y.H., Lee H.C., Chen K.H., Lee Y.M., Chan Y.J., Lien T.C., Jap T.S., Lin C.H., Kao L.S., and Chen Y.M. Open reading frame 8a of the human severe acute respiratory syndrome coronavirus not only promotes viral replication but also induces apoptosis. J. Infect. Dis. 196 (2007) 405-415
    • (2007) J. Infect. Dis. , vol.196 , pp. 405-415
    • Chen, C.Y.1    Ping, Y.H.2    Lee, H.C.3    Chen, K.H.4    Lee, Y.M.5    Chan, Y.J.6    Lien, T.C.7    Jap, T.S.8    Lin, C.H.9    Kao, L.S.10    Chen, Y.M.11
  • 4
    • 0033998035 scopus 로고    scopus 로고
    • Infectious bronchitis virus E protein is targeted to the Golgi complex and directs release of virus-like particles
    • Corse E., and Machamer C.E. Infectious bronchitis virus E protein is targeted to the Golgi complex and directs release of virus-like particles. J. Virol. 74 (2000) 4319-4326
    • (2000) J. Virol. , vol.74 , pp. 4319-4326
    • Corse, E.1    Machamer, C.E.2
  • 5
    • 0036145302 scopus 로고    scopus 로고
    • The cytoplasmic tail of infectious bronchitis virus E protein directs Golgi targeting
    • Corse E., and Machamer C.E. The cytoplasmic tail of infectious bronchitis virus E protein directs Golgi targeting. J. Virol. 76 (2002) 1273-1284
    • (2002) J. Virol. , vol.76 , pp. 1273-1284
    • Corse, E.1    Machamer, C.E.2
  • 6
    • 0042167579 scopus 로고    scopus 로고
    • The cytoplasmic tails of infectious bronchitis virus E and M proteins mediate their interaction
    • Corse E., and Machamer C.E. The cytoplasmic tails of infectious bronchitis virus E and M proteins mediate their interaction. Virology 312 (2003) 25-34
    • (2003) Virology , vol.312 , pp. 25-34
    • Corse, E.1    Machamer, C.E.2
  • 7
    • 0031950008 scopus 로고    scopus 로고
    • Coronavirus particle assembly: primary structure requirements of the membrane protein
    • de Haan C.A.M., Kuo L., Masters P.S., Vennema H., and Rottier P.J.M. Coronavirus particle assembly: primary structure requirements of the membrane protein. J. Virol. 72 (1998) 6838-6850
    • (1998) J. Virol. , vol.72 , pp. 6838-6850
    • de Haan, C.A.M.1    Kuo, L.2    Masters, P.S.3    Vennema, H.4    Rottier, P.J.M.5
  • 8
    • 0036343241 scopus 로고    scopus 로고
    • The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host
    • de Haan C.A.M., Masters P.S., Shen S., Weiss S., and Rottier P.J.M. The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host. Virology 296 (2002) 177-189
    • (2002) Virology , vol.296 , pp. 177-189
    • de Haan, C.A.M.1    Masters, P.S.2    Shen, S.3    Weiss, S.4    Rottier, P.J.M.5
  • 10
    • 36148979683 scopus 로고    scopus 로고
    • Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus
    • Devaraj S.G., Wang N., Chen Z., Chen Z., Tseng M., Barretto N., Lin R., Peters C.J., Tseng C.T., Baker S.C., and Li K. Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus. J. Biol. Chem. 282 (2007) 32208-32221
    • (2007) J. Biol. Chem. , vol.282 , pp. 32208-32221
    • Devaraj, S.G.1    Wang, N.2    Chen, Z.3    Chen, Z.4    Tseng, M.5    Barretto, N.6    Lin, R.7    Peters, C.J.8    Tseng, C.T.9    Baker, S.C.10    Li, K.11
  • 13
    • 0018756890 scopus 로고
    • Regulation of the interferon system: evidence that Vero cells have a genetic defect in interferon production
    • Emeny J.M., and Morgan M.J. Regulation of the interferon system: evidence that Vero cells have a genetic defect in interferon production. J. Gen. Virol. 43 (1979) 247-252
    • (1979) J. Gen. Virol. , vol.43 , pp. 247-252
    • Emeny, J.M.1    Morgan, M.J.2
  • 14
    • 40749108947 scopus 로고    scopus 로고
    • Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease
    • Enjuanes L., DeDiego M.L., Alvarez E., Deming D., Sheahan T., and Baric R. Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease. Virus Res. 133 (2008) 45-62
    • (2008) Virus Res. , vol.133 , pp. 45-62
    • Enjuanes, L.1    DeDiego, M.L.2    Alvarez, E.3    Deming, D.4    Sheahan, T.5    Baric, R.6
  • 16
    • 0031689187 scopus 로고    scopus 로고
    • Analysis of constructed E gene mutants of mouse hepatitis virus confirms a pivotal role for E protein in coronavirus assembly
    • Fischer F., Stegen C.F., Masters P.S., and Samsonoff W.A. Analysis of constructed E gene mutants of mouse hepatitis virus confirms a pivotal role for E protein in coronavirus assembly. J. Virol. 72 (1998) 7885-7894
    • (1998) J. Virol. , vol.72 , pp. 7885-7894
    • Fischer, F.1    Stegen, C.F.2    Masters, P.S.3    Samsonoff, W.A.4
  • 19
    • 35348845802 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane
    • Frieman M., Yount B., Heise M., Kopecky-Bromberg S.A., Palese P., and Baric R.S. Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane. J. Virol. 81 (2007) 9812-9824
    • (2007) J. Virol. , vol.81 , pp. 9812-9824
    • Frieman, M.1    Yount, B.2    Heise, M.3    Kopecky-Bromberg, S.A.4    Palese, P.5    Baric, R.S.6
  • 20
    • 3142751194 scopus 로고    scopus 로고
    • Discovery of novel human and animal cells infected by the severe acute respiratory syndrome coronavirus by replication-specific multiplex reverse transcription-PCR
    • Gillim-Ross L., Taylor J., Scholl D.R., Ridenour J., Masters P.S., and Wentworth D.E. Discovery of novel human and animal cells infected by the severe acute respiratory syndrome coronavirus by replication-specific multiplex reverse transcription-PCR. J. Clin. Microbiol. 42 (2004) 3196-3206
    • (2004) J. Clin. Microbiol. , vol.42 , pp. 3196-3206
    • Gillim-Ross, L.1    Taylor, J.2    Scholl, D.R.3    Ridenour, J.4    Masters, P.S.5    Wentworth, D.E.6
  • 21
    • 3242695128 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus phylogeny: toward consensus
    • Gorbalenya A.E., Snijder E.J., and Spaan W.J. Severe acute respiratory syndrome coronavirus phylogeny: toward consensus. J. Virol. 78 (2004) 7863-7866
    • (2004) J. Virol. , vol.78 , pp. 7863-7866
    • Gorbalenya, A.E.1    Snijder, E.J.2    Spaan, W.J.3
  • 24
    • 1842432528 scopus 로고    scopus 로고
    • Live, attenuated coronavirus vaccines through the directed deletion of group-specific genes provide protection against feline infectious peritonitis
    • Haijema B.J., Volders H., and Rottier P.J. Live, attenuated coronavirus vaccines through the directed deletion of group-specific genes provide protection against feline infectious peritonitis. J. Virol. 78 (2004) 3863-3871
    • (2004) J. Virol. , vol.78 , pp. 3863-3871
    • Haijema, B.J.1    Volders, H.2    Rottier, P.J.3
  • 26
    • 33746190729 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus 7a accessory protein is a viral structural protein
    • Huang C., Ito N., Tseng C.T., and Makino S. Severe acute respiratory syndrome coronavirus 7a accessory protein is a viral structural protein. J. Virol. 80 (2006) 7287-7294
    • (2006) J. Virol. , vol.80 , pp. 7287-7294
    • Huang, C.1    Ito, N.2    Tseng, C.T.3    Makino, S.4
  • 27
    • 34248329573 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus accessory protein 6 is a virion-associated protein and is released from 6 protein-expressing cells
    • Huang C., Peters C.J., and Makino S. Severe acute respiratory syndrome coronavirus accessory protein 6 is a virion-associated protein and is released from 6 protein-expressing cells. J. Virol. 81 (2007) 5423-5426
    • (2007) J. Virol. , vol.81 , pp. 5423-5426
    • Huang, C.1    Peters, C.J.2    Makino, S.3
  • 29
    • 28044467101 scopus 로고    scopus 로고
    • Human coronavirus NL63 associated with lower respiratory tract symptoms in early life
    • Kaiser L., Regamey N., Roiha H., Deffernez C., and Frey U. Human coronavirus NL63 associated with lower respiratory tract symptoms in early life. Pediatr. Infect. Dis. J. 24 (2005) 1015-1017
    • (2005) Pediatr. Infect. Dis. J. , vol.24 , pp. 1015-1017
    • Kaiser, L.1    Regamey, N.2    Roiha, H.3    Deffernez, C.4    Frey, U.5
  • 30
    • 33750969349 scopus 로고    scopus 로고
    • Over-expression of severe acute respiratory syndrome coronavirus 3b protein induces both apoptosis and necrosis in Vero E6 cells
    • Khan S., Fielding B.C., Tan T.H., Chou C.F., Shen S., Lim S.G., Hong W., and Tan Y.J. Over-expression of severe acute respiratory syndrome coronavirus 3b protein induces both apoptosis and necrosis in Vero E6 cells. Virus Res. 122 (2006) 20-27
    • (2006) Virus Res. , vol.122 , pp. 20-27
    • Khan, S.1    Fielding, B.C.2    Tan, T.H.3    Chou, C.F.4    Shen, S.5    Lim, S.G.6    Hong, W.7    Tan, Y.J.8
  • 31
    • 27644584129 scopus 로고    scopus 로고
    • Modulation of the immune response to the severe acute respiratory syndrome spike glycoprotein by gene-based and inactivated virus immunization
    • Kong W.P., Xu L., Stadler K., Ulmer J.B., Abrignani S., Rappuoli R., and Nabel G.J. Modulation of the immune response to the severe acute respiratory syndrome spike glycoprotein by gene-based and inactivated virus immunization. J. Virol. 79 (2005) 13915-13923
    • (2005) J. Virol. , vol.79 , pp. 13915-13923
    • Kong, W.P.1    Xu, L.2    Stadler, K.3    Ulmer, J.B.4    Abrignani, S.5    Rappuoli, R.6    Nabel, G.J.7
  • 32
    • 33846104528 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists
    • Kopecky-Bromberg S.A., Martinez-Sobrido L., Frieman M., Baric R.A., and Palese P. Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists. J. Virol. 81 (2007) 548-557
    • (2007) J. Virol. , vol.81 , pp. 548-557
    • Kopecky-Bromberg, S.A.1    Martinez-Sobrido, L.2    Frieman, M.3    Baric, R.A.4    Palese, P.5
  • 35
    • 0037383461 scopus 로고    scopus 로고
    • The small envelope protein E is not essential for murine coronavirus replication
    • Kuo L., and Masters P.S. The small envelope protein E is not essential for murine coronavirus replication. J. Virol. 77 (2003) 4597-4608
    • (2003) J. Virol. , vol.77 , pp. 4597-4608
    • Kuo, L.1    Masters, P.S.2
  • 36
    • 33745418278 scopus 로고    scopus 로고
    • Accelerated induction of apoptosis in insect cells by baculovirus-expressed SARS-CoV membrane protein
    • Lai C.W., Chan Z.R., Yang D.G., Lo W.H., Lai Y.K., Chang M.D., and Hu Y.C. Accelerated induction of apoptosis in insect cells by baculovirus-expressed SARS-CoV membrane protein. FEBS Lett. 580 (2006) 3829-3834
    • (2006) FEBS Lett. , vol.580 , pp. 3829-3834
    • Lai, C.W.1    Chan, Z.R.2    Yang, D.G.3    Lo, W.H.4    Lai, Y.K.5    Chang, M.D.6    Hu, Y.C.7
  • 39
    • 12844278641 scopus 로고    scopus 로고
    • Factors associated with psychosis among patients with severe acute respiratory syndrome: a case-control study
    • Lee D.T., Wing Y.K., Leung H.C., Sung J.J., Ng Y.K., Yiu G.C., Chen R.Y., and Chiu H.F. Factors associated with psychosis among patients with severe acute respiratory syndrome: a case-control study. Clin. Infect. Dis. 39 (2004) 1247-1249
    • (2004) Clin. Infect. Dis. , vol.39 , pp. 1247-1249
    • Lee, D.T.1    Wing, Y.K.2    Leung, H.C.3    Sung, J.J.4    Ng, Y.K.5    Yiu, G.C.6    Chen, R.Y.7    Chiu, H.F.8
  • 44
    • 14744273484 scopus 로고    scopus 로고
    • Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication
    • Mossel E.C., Huang C., Narayanan K., Makino S., Tesh R.B., and Peters C.J. Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication. J. Virol. 79 (2005) 3846-3850
    • (2005) J. Virol. , vol.79 , pp. 3846-3850
    • Mossel, E.C.1    Huang, C.2    Narayanan, K.3    Makino, S.4    Tesh, R.B.5    Peters, C.J.6
  • 45
    • 11844281552 scopus 로고    scopus 로고
    • Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein
    • Nelson C.A., Pekosz A., Lee C.A., Diamond M.S., and Fremont D.H. Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein. Structure 13 (2005) 75-85
    • (2005) Structure , vol.13 , pp. 75-85
    • Nelson, C.A.1    Pekosz, A.2    Lee, C.A.3    Diamond, M.S.4    Fremont, D.H.5
  • 46
    • 0348013197 scopus 로고    scopus 로고
    • Proliferative growth of SARS coronavirus in Vero E6 cells
    • Ng M.L., Tan S.H., See E.E., Ooi E.E., and Ling A.E. Proliferative growth of SARS coronavirus in Vero E6 cells. J. Gen. Virol. 84 (2003) 3291-3303
    • (2003) J. Gen. Virol. , vol.84 , pp. 3291-3303
    • Ng, M.L.1    Tan, S.H.2    See, E.E.3    Ooi, E.E.4    Ling, A.E.5
  • 47
    • 0035950592 scopus 로고    scopus 로고
    • Inactivation of expression of gene 4 of mouse hepatitis virus strain JHM does not affect virulence in the murine CNS
    • Ontiveros E., Kuo L., Masters P.S., and Perlman S. Inactivation of expression of gene 4 of mouse hepatitis virus strain JHM does not affect virulence in the murine CNS. Virology 289 (2001) 230-238
    • (2001) Virology , vol.289 , pp. 230-238
    • Ontiveros, E.1    Kuo, L.2    Masters, P.S.3    Perlman, S.4
  • 48
    • 0037473293 scopus 로고    scopus 로고
    • Transmissible gastroenteritis coronavirus gene 7 is not essential but influences in vivo virus replication and virulence
    • Ortego J., Sola I., Almazan F., Ceriani J.E., Riquelme C., Balasch M., Plana-Durán J., and Enjuanes L. Transmissible gastroenteritis coronavirus gene 7 is not essential but influences in vivo virus replication and virulence. Virology 308 (2003) 13-22
    • (2003) Virology , vol.308 , pp. 13-22
    • Ortego, J.1    Sola, I.2    Almazan, F.3    Ceriani, J.E.4    Riquelme, C.5    Balasch, M.6    Plana-Durán, J.7    Enjuanes, L.8
  • 50
    • 23844554435 scopus 로고    scopus 로고
    • A severe acute respiratory syndrome-associated coronavirus-specific protein enhances virulence of an attenuated murine coronavirus
    • Pewe L., Zhou H., Netland J., Tangudu C., Olivares H., Shi L., Look D., Gallagher T., and Perlman S. A severe acute respiratory syndrome-associated coronavirus-specific protein enhances virulence of an attenuated murine coronavirus. J. Virol. 79 (2005) 11335-11342
    • (2005) J. Virol. , vol.79 , pp. 11335-11342
    • Pewe, L.1    Zhou, H.2    Netland, J.3    Tangudu, C.4    Olivares, H.5    Shi, L.6    Look, D.7    Gallagher, T.8    Perlman, S.9
  • 52
    • 10444272332 scopus 로고    scopus 로고
    • Intranasal immunization with inactivated SARS-CoV (SARS-associated coronavirus) induced local and serum antibodies in mice
    • Qu D., Zheng B., Yao X., Guan Y., Yuan Z.H., Zhong N.S., Lu L.W., Xie J.P., and Wen Y.M. Intranasal immunization with inactivated SARS-CoV (SARS-associated coronavirus) induced local and serum antibodies in mice. Vaccine 23 (2005) 924-931
    • (2005) Vaccine , vol.23 , pp. 924-931
    • Qu, D.1    Zheng, B.2    Yao, X.3    Guan, Y.4    Yuan, Z.H.5    Zhong, N.S.6    Lu, L.W.7    Xie, J.P.8    Wen, Y.M.9
  • 55
    • 0344069787 scopus 로고    scopus 로고
    • Targeted recombination demonstrates that the spike gene of transmissible gastroenteritis coronavirus is a determinant of its enteric tropism and virulence
    • Sanchez C.M., Izeta A., Sánchez-Morgado J.M., Alonso S., Sola I., Balasch M., Plana-Duran J., and Enjuanes L. Targeted recombination demonstrates that the spike gene of transmissible gastroenteritis coronavirus is a determinant of its enteric tropism and virulence. J. Virol. 73 (1999) 7607-7618
    • (1999) J. Virol. , vol.73 , pp. 7607-7618
    • Sanchez, C.M.1    Izeta, A.2    Sánchez-Morgado, J.M.3    Alonso, S.4    Sola, I.5    Balasch, M.6    Plana-Duran, J.7    Enjuanes, L.8
  • 56
    • 33846060748 scopus 로고    scopus 로고
    • The ORF7b protein of SARS-CoV is expressed in virus-infected cells and incorporated into SARS-CoV particles
    • Schaecher S.R., Mackenzie J.M., and Pekosz A. The ORF7b protein of SARS-CoV is expressed in virus-infected cells and incorporated into SARS-CoV particles. J. Virol. 81 (2007) 718-731
    • (2007) J. Virol. , vol.81 , pp. 718-731
    • Schaecher, S.R.1    Mackenzie, J.M.2    Pekosz, A.3
  • 58
    • 40649099135 scopus 로고    scopus 로고
    • SARS-CoV replication and pathogenesis in an in vitro model of the human conducting airway epithelium
    • Sims A.C., Burkett S.E., Yount B., and Pickles R.J. SARS-CoV replication and pathogenesis in an in vitro model of the human conducting airway epithelium. Virus Res. 133 (2008) 33-44
    • (2008) Virus Res. , vol.133 , pp. 33-44
    • Sims, A.C.1    Burkett, S.E.2    Yount, B.3    Pickles, R.J.4
  • 61
    • 33745514661 scopus 로고    scopus 로고
    • Is there an ideal animal model for SARS?
    • Subbarao K., and Roberts A. Is there an ideal animal model for SARS?. Trends Microbiol. 14 (2006) 299-303
    • (2006) Trends Microbiol. , vol.14 , pp. 299-303
    • Subbarao, K.1    Roberts, A.2
  • 62
    • 1242290470 scopus 로고    scopus 로고
    • Poliovirus vaccine-Live
    • Plotkin S.A., and Orenstein W.A. (Eds), Elsevier, Philadelphia
    • Sutter R.W., Kew O.M., and Cochi S.M. Poliovirus vaccine-Live. In: Plotkin S.A., and Orenstein W.A. (Eds). Vaccines. 4th ed. (2004), Elsevier, Philadelphia 651-705
    • (2004) Vaccines. 4th ed. , pp. 651-705
    • Sutter, R.W.1    Kew, O.M.2    Cochi, S.M.3
  • 63
    • 34249951949 scopus 로고    scopus 로고
    • Induction of apoptosis by the severe acute respiratory syndrome coronavirus 7a protein is dependent on its interaction with the Bcl-xl protein
    • Tan Y.X., Tan T.H., Lee M.J., Tham P.Y., Gunalan V., Druce J., Birch C., Catton M., Fu N.Y., Yu V.C., and Tan Y.J. Induction of apoptosis by the severe acute respiratory syndrome coronavirus 7a protein is dependent on its interaction with the Bcl-xl protein. J. Virol. 81 (2007) 6346-6355
    • (2007) J. Virol. , vol.81 , pp. 6346-6355
    • Tan, Y.X.1    Tan, T.H.2    Lee, M.J.3    Tham, P.Y.4    Gunalan, V.5    Druce, J.6    Birch, C.7    Catton, M.8    Fu, N.Y.9    Yu, V.C.10    Tan, Y.J.11
  • 64
    • 33846513930 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus protein 6 accelerates murine coronavirus infections
    • Tangudu C., Olivares H., Netland J., Perlman S., and Gallagher T. Severe acute respiratory syndrome coronavirus protein 6 accelerates murine coronavirus infections. J. Virol. 81 (2007) 1220-1229
    • (2007) J. Virol. , vol.81 , pp. 1220-1229
    • Tangudu, C.1    Olivares, H.2    Netland, J.3    Perlman, S.4    Gallagher, T.5
  • 68
    • 35448939321 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain
    • Wathelet M.G., Orr M., Frieman M.B., and Baric R.S. Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain. J. Virol. 81 (2007) 11620-11633
    • (2007) J. Virol. , vol.81 , pp. 11620-11633
    • Wathelet, M.G.1    Orr, M.2    Frieman, M.B.3    Baric, R.S.4
  • 69
    • 29144451985 scopus 로고    scopus 로고
    • Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus
    • Weiss S.R., and Navas-Martin S. Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus. Microbiol. Mol. Biol. Rev. 69 (2005) 635-664
    • (2005) Microbiol. Mol. Biol. Rev. , vol.69 , pp. 635-664
    • Weiss, S.R.1    Navas-Martin, S.2
  • 71
    • 26444530999 scopus 로고    scopus 로고
    • Detection of severe acute respiratory syndrome coronavirus in the brain: potential role of the chemokine mig in pathogenesis
    • Xu J., Zhong S., Liu J., Li L., Li Y., Wu X., Li Z., Deng P., Zhang J., Zhong N., Ding Y., and Jiang Y. Detection of severe acute respiratory syndrome coronavirus in the brain: potential role of the chemokine mig in pathogenesis. Clin. Infect. Dis. 41 (2005) 1089-1096
    • (2005) Clin. Infect. Dis. , vol.41 , pp. 1089-1096
    • Xu, J.1    Zhong, S.2    Liu, J.3    Li, L.4    Li, Y.5    Wu, X.6    Li, Z.7    Deng, P.8    Zhang, J.9    Zhong, N.10    Ding, Y.11    Jiang, Y.12
  • 72
    • 28044447841 scopus 로고    scopus 로고
    • Bcl-xL inhibits T-cell apoptosis induced by expression of SARS coronavirus E protein in the absence of growth factors
    • Yang Y., Xiong Z., Zhang S., Yan Y., Nguyen J., Ng B., Lu H., Brendese J., Yang F., Wang H., and Yang X.F. Bcl-xL inhibits T-cell apoptosis induced by expression of SARS coronavirus E protein in the absence of growth factors. Biochem. J. 392 (2005) 135-143
    • (2005) Biochem. J. , vol.392 , pp. 135-143
    • Yang, Y.1    Xiong, Z.2    Zhang, S.3    Yan, Y.4    Nguyen, J.5    Ng, B.6    Lu, H.7    Brendese, J.8    Yang, F.9    Wang, H.10    Yang, X.F.11
  • 73
    • 27744472746 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice
    • Yount B., Roberts R.S., Sims A.C., Deming D., Frieman M.B., Sparks J., Denison M.R., Davis N., and Baric R.S. Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice. J. Virol. 79 (2005) 14909-14922
    • (2005) J. Virol. , vol.79 , pp. 14909-14922
    • Yount, B.1    Roberts, R.S.2    Sims, A.C.3    Deming, D.4    Frieman, M.B.5    Sparks, J.6    Denison, M.R.7    Davis, N.8    Baric, R.S.9
  • 75
    • 20144389472 scopus 로고    scopus 로고
    • Immunogenicity, safety, and protective efficacy of an inactivated SARS-associated coronavirus vaccine in rhesus monkeys
    • Zhou J., Wang W., Zhong Q., Hou W., Yang Z., Xiao S.Y., Zhu R., Tang Z., Wang Y., Xian Q., Tang H., and Wen L. Immunogenicity, safety, and protective efficacy of an inactivated SARS-associated coronavirus vaccine in rhesus monkeys. Vaccine 23 (2005) 3202-3209
    • (2005) Vaccine , vol.23 , pp. 3202-3209
    • Zhou, J.1    Wang, W.2    Zhong, Q.3    Hou, W.4    Yang, Z.5    Xiao, S.Y.6    Zhu, R.7    Tang, Z.8    Wang, Y.9    Xian, Q.10    Tang, H.11    Wen, L.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.