메뉴 건너뛰기




Volumn 285, Issue 1, 1998, Pages 119-126

Agonist and inverse agonist activity at the dopamine D3 receptor measured by guanosine 5'-[γ-thio]triphosphate-[35S] binding

Author keywords

[No Author keywords available]

Indexed keywords

2 DIPROPYLAMINO 5 METHOXY 1 METHYLTETRALIN; 2 DIPROPYLAMINO 7 HYDROXYTETRALIN; 5 METHOXY 1 METHYL 2 PROPYLAMINOTETRALIN; CLOZAPINE; DOPAMINE; DOPAMINE 2 RECEPTOR BLOCKING AGENT; DOPAMINE 3 RECEPTOR; GUANINE NUCLEOTIDE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); HALOPERIDOL; MAGNESIUM; PERTUSSIS TOXIN; PRECLAMOL; QUINPIROLE; RACLOPRIDE; SODIUM;

EID: 0031969706     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (57)

References (41)
  • 1
    • 0031037633 scopus 로고    scopus 로고
    • Pharmacology of muscarinic receptor subtypes constitutively activated by G proteins
    • Burstein ES, Spalding TA and Brann MR (1997) Pharmacology of muscarinic receptor subtypes constitutively activated by G proteins. Mol Pharmacol 51:312-319.
    • (1997) Mol Pharmacol , vol.51 , pp. 312-319
    • Burstein, E.S.1    Spalding, T.A.2    Brann, M.R.3
  • 4
    • 0026608113 scopus 로고
    • Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: Thermodynamic interpretation of negative antagonism and of receptor activity in the absence of ligand
    • Costa T, Ogino Y, Munson PJ, Onaran HO and Rodbard D (1992) Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: thermodynamic interpretation of negative antagonism and of receptor activity in the absence of ligand. Mol Pharmacol 41:549-560.
    • (1992) Mol Pharmacol , vol.41 , pp. 549-560
    • Costa, T.1    Ogino, Y.2    Munson, P.J.3    Onaran, H.O.4    Rodbard, D.5
  • 5
    • 0021064607 scopus 로고
    • Classical and atypical antipsychotic drugs: New insights
    • Creese I (1983) Classical and atypical antipsychotic drugs: new insights. Trends Neurosci 6:479-481.
    • (1983) Trends Neurosci , vol.6 , pp. 479-481
    • Creese, I.1
  • 6
    • 0019137579 scopus 로고
    • A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled b-adrenergic receptor
    • De Lean A, Stadel JM and Lefkowitz RJ (1980) A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled b-adrenergic receptor. J Biol Chem 255:7108-7117.
    • (1980) J Biol Chem , vol.255 , pp. 7108-7117
    • De Lean, A.1    Stadel, J.M.2    Lefkowitz, R.J.3
  • 9
    • 0031018485 scopus 로고    scopus 로고
    • Structural instability of a constitutively active G protein-coupled receptor-agonist-independent activation due to conformational flexibility
    • Gether U, Ballesteros JA, Seifert R, Sandersbush E, Weinstein H and Kobilka BK (1997) Structural instability of a constitutively active G protein-coupled receptor-agonist-independent activation due to conformational flexibility. J Biol Chem 272:2587-2590.
    • (1997) J Biol Chem , vol.272 , pp. 2587-2590
    • Gether, U.1    Ballesteros, J.A.2    Seifert, R.3    Sandersbush, E.4    Weinstein, H.5    Kobilka, B.K.6
  • 12
    • 0021870454 scopus 로고
    • 2 dopamine receptors from the high- to the low-affinity state for dopamine agonists, using sodium ions and guanine nucleotide
    • 2 dopamine receptors from the high-to the low-affinity state for dopamine agonists, using sodium ions and guanine nucleotide. J Neurochem 44:1925-1935.
    • (1985) J Neurochem , vol.44 , pp. 1925-1935
    • Grigoriadis, D.1    Seeman, P.2
  • 13
    • 0020001939 scopus 로고
    • 3H-Dopamine binding to rat striatal D-2 and D-3 sites: Enhancement by magnesium and inhibition by guanine nucleotides and sodium
    • 3H-Dopamine binding to rat striatal D-2 and D-3 sites: enhancement by magnesium and inhibition by guanine nucleotides and sodium. Life Sci 30:1587-1595.
    • (1982) Life Sci , vol.30 , pp. 1587-1595
    • Hamblin, M.W.1    Creese, I.2
  • 15
    • 0029162109 scopus 로고
    • Pharmacological Proteus?
    • Kenakin T (1995) Pharmacological Proteus? Trends Pharmacol Sci 16:256-258.
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 256-258
    • Kenakin, T.1
  • 16
    • 0018862848 scopus 로고
    • A quantitative analysis of beta-adrenergic receptor interactions: Resolution of high and low affinity states of the receptor by computer modeling of ligand binding data
    • Kent RS, De Lean A and Lefkowitz RJ (1980) A quantitative analysis of beta-adrenergic receptor interactions: resolution of high and low affinity states of the receptor by computer modeling of ligand binding data. Mol Pharmacol 17:14-23.
    • (1980) Mol Pharmacol , vol.17 , pp. 14-23
    • Kent, R.S.1    De Lean, A.2    Lefkowitz, R.J.3
  • 18
    • 0027525822 scopus 로고
    • Pharmacological characterization of guanine nucleotide exchange reactions in membranes from CHO cells stably transfected with human muscarinic receptors m1-m4
    • Lazareno S, Farries T and Birdsall NJM (1993) Pharmacological characterization of guanine nucleotide exchange reactions in membranes from CHO cells stably transfected with human muscarinic receptors m1-m4. Life Sci 52:449-456.
    • (1993) Life Sci , vol.52 , pp. 449-456
    • Lazareno, S.1    Farries, T.2    Birdsall, N.J.M.3
  • 19
    • 0027297275 scopus 로고
    • Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
    • Lefkowitz RJ, Cotecchia S, Samama P and Costa T (1993) Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol Sci 14:303-307.
    • (1993) Trends Pharmacol Sci , vol.14 , pp. 303-307
    • Lefkowitz, R.J.1    Cotecchia, S.2    Samama, P.3    Costa, T.4
  • 21
    • 0029926567 scopus 로고    scopus 로고
    • Novel (R)-2-amino-5-fluorotetralins - Dopaminergic antagonists and inverse agonists
    • Malmberg, Å., Backlund Höök B, Johansson AM and Hacksell U (1996) Novel (R)-2-amino-5-fluorotetralins - dopaminergic antagonists and inverse agonists. J Med Chem 39:4421-4429.
    • (1996) J Med Chem , vol.39 , pp. 4421-4429
    • Malmberg, Å.1    Backlund Höök, B.2    Johansson, A.M.3    Hacksell, U.4
  • 23
    • 0028978258 scopus 로고
    • 3 receptors: Effects of ions and guanine nucleotides
    • 3 receptors: Effects of ions and guanine nucleotides. J Pharmacol Exp Ther 274:790-797.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 790-797
    • Malmberg, Å.1    Mohell, N.2
  • 24
    • 0018178434 scopus 로고
    • A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples
    • Markwell MAK, Haas SM, Bieber LL and Tolbert NE (1978) A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal Biochem 87:206-210.
    • (1978) Anal Biochem , vol.87 , pp. 206-210
    • Markwell, M.A.K.1    Haas, S.M.2    Bieber, L.L.3    Tolbert, N.E.4
  • 25
    • 0019061918 scopus 로고
    • LIGAND: A versatile computerized approach for characterization of ligand-binding systems
    • Munson PJ and Rodhard D (1980) LIGAND: A versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 107:220-239.
    • (1980) Anal Biochem , vol.107 , pp. 220-239
    • Munson, P.J.1    Rodhard, D.2
  • 29
    • 0026501003 scopus 로고
    • Developments in the drug treatment of schizophrenia
    • Reynolds GP (1992) Developments in the drug treatment of schizophrenia. Trends Pharmacol Sci 13:116-121.
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 116-121
    • Reynolds, G.P.1
  • 34
    • 0023254675 scopus 로고
    • Dopamine receptors and the dopamine hypothesis of schizophrenia
    • Seeman P (1987) Dopamine receptors and the dopamine hypothesis of schizophrenia. Synapse 1:133-152.
    • (1987) Synapse , vol.1 , pp. 133-152
    • Seeman, P.1
  • 35
    • 0026481115 scopus 로고
    • Dopamine receptor sequences. Therapeutic levels of neuroleptics occupy D2 receptors, clozapine occupies D4
    • Seeman P (1992) Dopamine receptor sequences. Therapeutic levels of neuroleptics occupy D2 receptors, clozapine occupies D4. Neuropsychopharmacology 7:261-284.
    • (1992) Neuropsychopharmacology , vol.7 , pp. 261-284
    • Seeman, P.1
  • 39
    • 0024307884 scopus 로고
    • 2 receptors for dopamine by a mechanism independent of receptor coupling to guanyl nucleotide binding proteins
    • 2 receptors for dopamine by a mechanism independent of receptor coupling to guanyl nucleotide binding proteins. Naunyn-Schmiedebergs Arch Pharmacol 339: 374-382.
    • (1989) Naunyn-Schmiedebergs Arch Pharmacol , vol.339 , pp. 374-382
    • Urwyler, S.1
  • 41
    • 0028314995 scopus 로고
    • Measurements of receptor-stimulated guanosine 5′-O-(γ-thio)triphosphate binding by G proteins
    • (Iyengar R ed) Academic Press, Inc. San Diego, CA
    • Wieland T and Jakobs KH (1994) Measurements of receptor-stimulated guanosine 5′-O-(γ-thio)triphosphate binding by G proteins, in Heterotrimeric G Proteins (Iyengar R ed) pp 3-13, Academic Press, Inc. San Diego, CA.
    • (1994) Heterotrimeric G Proteins , pp. 3-13
    • Wieland, T.1    Jakobs, K.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.