The synthetic peroxisome proliferator-activated receptor-α agonist ciglitazone attenuates neuroinflammation and accelerates encapsulation in bacterial brain abscesses

Journal of Immunology

Volumn 180, Issue 7, 2008, Pages 5004-5016

  Kielian, Tammy ^a   Syed, Mohsin Md ^a   Liu, Shuliang ^a   Phulwani, Nirmal K ^a   Phillips, Napoleon ^a   Wagoner, Gail ^a   Drew, Paul D ^a   Esen, Nilufer ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CIGLITAZONE; CXCL2 CHEMOKINE; FIBRONECTIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; TUMOR NECROSIS FACTOR ALPHA; 2,4 THIAZOLIDINEDIONE DERIVATIVE; LIGAND; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEOGLYCAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ABSCESS; BRAIN INFECTION; CONTROLLED STUDY; DRUG MECHANISM; ENCAPSULATION; FEMALE; MACROPHAGE ACTIVATION; MALE; MICROGLIA; MOUSE; MYOFIBROBLAST; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAPHYLOCOCCUS AUREUS; ANIMAL; C57BL MOUSE; CELL WALL; CHEMISTRY; DRUG EFFECT; DRUG POTENTIATION; IMMUNOLOGY; INFLAMMATION; MACROPHAGE; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; SENSITIVITY AND SPECIFICITY; STAPHYLOCOCCUS INFECTION; SYNTHESIS;

ANIMALS; BRAIN ABSCESS; CELL WALL; FIBRONECTINS; INFLAMMATION; LIGANDS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICROBIAL VIABILITY; MICROGLIA; NITRIC OXIDE SYNTHASE TYPE II; PHAGOCYTOSIS; PPAR GAMMA; PROTEOGLYCANS; SENSITIVITY AND SPECIFICITY; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; THIAZOLIDINEDIONES;

EID: 44449147861     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.7.5004     Document Type: Article

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