Structural dynamics in the activation of Epac

Journal of Biological Chemistry

Volumn 283, Issue 10, 2008, Pages 6501-6508

  Harper, Shannon M ^a   Wienk, Hans ^b   Wechselberger, Rainer W ^b   Bos, Johannes L ^a   Boelens, Rolf ^b,c   Rehmann, Holger ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DYNAMICS; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEIC ACIDS; NUCLEOTIDES; STRUCTURAL DYNAMICS;

ACTIVATION MECHANISMS; ACTIVE CONFORMATIONS; CATALYTIC SITES; CONFORMATIONAL CHANGES; CONFORMATIONAL STATES; CRITICAL ELEMENTS; CYCLIC NUCLEOTIDES; DO-MAINS; EXCHANGE FACTORS; HELICAL SEGMENTS; INTERNAL MOBILITIES; LIGAND BINDING POCKETS; NMR SPECTROSCOPIES; REGULATORY REGIONS;

FETAL MONITORING;

PROTEIN; PROTEIN EPAC; UNCLASSIFIED DRUG; CYCLIC AMP; DRUG DERIVATIVE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; LIGAND; RAPGEF3 PROTEIN, HUMAN; RAPGEF4 PROTEIN, HUMAN; TELOMERE BINDING PROTEIN; TERF2IP PROTEIN, HUMAN;

ARTICLE; CONFORMATIONAL TRANSITION; LIGAND BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; STRUCTURE ANALYSIS; ANIMAL; CHEMISTRY; GENETICS; HUMAN; METABOLISM; NUCLEAR MAGNETIC RESONANCE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ANIMALS; CYCLIC AMP; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; LIGANDS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, TERTIARY; TELOMERE-BINDING PROTEINS;

EID: 44449130112     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M707849200     Document Type: Article

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