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Volumn 30, Issue 5, 2008, Pages 567-577

Transcription Initiation in a Single-Subunit RNA Polymerase Proceeds through DNA Scrunching and Rotation of the N-Terminal Subdomains

Author keywords

DNA; PROTEINS

Indexed keywords

RNA POLYMERASE;

EID: 44449127089     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2008.04.003     Document Type: Article
Times cited : (39)

References (55)
  • 1
    • 33745232330 scopus 로고    scopus 로고
    • Sequential release of promoter contacts during transcription initiation to elongation transition
    • Bandwar R.P., Tang G.Q., and Patel S.S. Sequential release of promoter contacts during transcription initiation to elongation transition. J. Mol. Biol. 360 (2006) 466-483
    • (2006) J. Mol. Biol. , vol.360 , pp. 466-483
    • Bandwar, R.P.1    Tang, G.Q.2    Patel, S.S.3
  • 3
    • 0038013991 scopus 로고    scopus 로고
    • RNA polymerase holoenzyme: structure, function and biological implications
    • Borukhov S., and Nudler E. RNA polymerase holoenzyme: structure, function and biological implications. Curr. Opin. Microbiol. 6 (2003) 93-100
    • (2003) Curr. Opin. Microbiol. , vol.6 , pp. 93-100
    • Borukhov, S.1    Nudler, E.2
  • 4
    • 0035803474 scopus 로고    scopus 로고
    • T7 promoter release mediated by DNA scrunching
    • Brieba L.G., and Sousa R. T7 promoter release mediated by DNA scrunching. EMBO J. 20 (2001) 6826-6835
    • (2001) EMBO J. , vol.20 , pp. 6826-6835
    • Brieba, L.G.1    Sousa, R.2
  • 5
    • 0022247421 scopus 로고
    • Interaction of RNA polymerase with lacUV5 promoter DNA during mRNA initiation and elongation. Footprinting, methylation, and rifampicin-sensitivity changes accompanying transcription initiation
    • Carpousis A.J., and Gralla J.D. Interaction of RNA polymerase with lacUV5 promoter DNA during mRNA initiation and elongation. Footprinting, methylation, and rifampicin-sensitivity changes accompanying transcription initiation. J. Mol. Biol. 183 (1985) 165-177
    • (1985) J. Mol. Biol. , vol.183 , pp. 165-177
    • Carpousis, A.J.1    Gralla, J.D.2
  • 6
    • 0033579380 scopus 로고    scopus 로고
    • Structure of a transcribing T7 RNA polymerase initiation complex
    • Cheetham G.M., and Steitz T.A. Structure of a transcribing T7 RNA polymerase initiation complex. Science 286 (1999) 2305-2309
    • (1999) Science , vol.286 , pp. 2305-2309
    • Cheetham, G.M.1    Steitz, T.A.2
  • 7
    • 0032450641 scopus 로고    scopus 로고
    • Transcription regulation, initiation, and "DNA scrunching" by T7 RNA polymerase
    • Cheetham G.M., Jeruzalmi D., and Steitz T.A. Transcription regulation, initiation, and "DNA scrunching" by T7 RNA polymerase. Cold Spring Harb. Symp. Quant. Biol. 63 (1998) 263-267
    • (1998) Cold Spring Harb. Symp. Quant. Biol. , vol.63 , pp. 263-267
    • Cheetham, G.M.1    Jeruzalmi, D.2    Steitz, T.A.3
  • 8
    • 0033529089 scopus 로고    scopus 로고
    • Structural basis for initiation of transcription from an RNA polymerase-promoter complex
    • Cheetham G.M., Jeruzalmi D., and Steitz T.A. Structural basis for initiation of transcription from an RNA polymerase-promoter complex. Nature 399 (1999) 80-83
    • (1999) Nature , vol.399 , pp. 80-83
    • Cheetham, G.M.1    Jeruzalmi, D.2    Steitz, T.A.3
  • 9
    • 0026687952 scopus 로고
    • Fluorescence resonance energy transfer and nucleic acids
    • Clegg R.M. Fluorescence resonance energy transfer and nucleic acids. Methods Enzymol. 211 (1992) 353-388
    • (1992) Methods Enzymol. , vol.211 , pp. 353-388
    • Clegg, R.M.1
  • 11
    • 0033616580 scopus 로고    scopus 로고
    • Single-pair fluorescence resonance energy transfer on freely diffusing molecules: observation of Forster distance dependence and subpopulations
    • Deniz A.A., Dahan M., Grunwell J.R., Ha T., Faulhaber A.E., Chemla D.S., Weiss S., and Schultz P.G. Single-pair fluorescence resonance energy transfer on freely diffusing molecules: observation of Forster distance dependence and subpopulations. Proc. Natl. Acad. Sci. USA 96 (1999) 3670-3675
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3670-3675
    • Deniz, A.A.1    Dahan, M.2    Grunwell, J.R.3    Ha, T.4    Faulhaber, A.E.5    Chemla, D.S.6    Weiss, S.7    Schultz, P.G.8
  • 12
    • 7244227984 scopus 로고    scopus 로고
    • Cross-linking of promoter DNA to T7 RNA polymerase does not prevent formation of a stable elongation complex
    • Esposito E.A., and Martin C.T. Cross-linking of promoter DNA to T7 RNA polymerase does not prevent formation of a stable elongation complex. J. Biol. Chem. 279 (2004) 44270-44276
    • (2004) J. Biol. Chem. , vol.279 , pp. 44270-44276
    • Esposito, E.A.1    Martin, C.T.2
  • 13
    • 4944262080 scopus 로고    scopus 로고
    • Initial bubble collapse plays a key role in the transition to elongation in T7 RNA polymerase
    • Gong P., Esposito E.A., and Martin C.T. Initial bubble collapse plays a key role in the transition to elongation in T7 RNA polymerase. J. Biol. Chem. 279 (2004) 44277-44285
    • (2004) J. Biol. Chem. , vol.279 , pp. 44277-44285
    • Gong, P.1    Esposito, E.A.2    Martin, C.T.3
  • 15
    • 13544264391 scopus 로고    scopus 로고
    • Multiple roles for the T7 promoter nontemplate strand during transcription initiation and polymerase release
    • Guo Q., and Sousa R. Multiple roles for the T7 promoter nontemplate strand during transcription initiation and polymerase release. J. Biol. Chem. 280 (2005) 3474-3482
    • (2005) J. Biol. Chem. , vol.280 , pp. 3474-3482
    • Guo, Q.1    Sousa, R.2
  • 16
    • 25144515314 scopus 로고    scopus 로고
    • Major conformational changes during T7RNAP transcription initiation coincide with, and are required for, promoter release
    • Guo Q., Nayak D., Brieba L.G., and Sousa R. Major conformational changes during T7RNAP transcription initiation coincide with, and are required for, promoter release. J. Mol. Biol. 353 (2005) 256-270
    • (2005) J. Mol. Biol. , vol.353 , pp. 256-270
    • Guo, Q.1    Nayak, D.2    Brieba, L.G.3    Sousa, R.4
  • 17
    • 0029987587 scopus 로고    scopus 로고
    • Probing the interaction between two single molecules: fluorescence resonance energy transfer between a single donor and a single acceptor
    • Ha T., Enderle T., Ogletree D.F., Chemla D.S., Selvin P.R., and Weiss S. Probing the interaction between two single molecules: fluorescence resonance energy transfer between a single donor and a single acceptor. Proc. Natl. Acad. Sci. USA 93 (1996) 6264-6268
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6264-6268
    • Ha, T.1    Enderle, T.2    Ogletree, D.F.3    Chemla, D.S.4    Selvin, P.R.5    Weiss, S.6
  • 19
    • 0031046587 scopus 로고    scopus 로고
    • A mutant T7 RNA polymerase that is defective in RNA binding and blocked in the early stages of transcription
    • He B., Rong M., Durbin R.K., and McAllister W.T. A mutant T7 RNA polymerase that is defective in RNA binding and blocked in the early stages of transcription. J. Mol. Biol. 265 (1997) 275-288
    • (1997) J. Mol. Biol. , vol.265 , pp. 275-288
    • He, B.1    Rong, M.2    Durbin, R.K.3    McAllister, W.T.4
  • 20
    • 33746303519 scopus 로고    scopus 로고
    • An 8 nt RNA triggers a rate-limiting shift of RNA polymerase II complexes into elongation
    • Hieb A.R., Baran S., Goodrich J.A., and Kugel J.F. An 8 nt RNA triggers a rate-limiting shift of RNA polymerase II complexes into elongation. EMBO J. 25 (2006) 3100-3109
    • (2006) EMBO J. , vol.25 , pp. 3100-3109
    • Hieb, A.R.1    Baran, S.2    Goodrich, J.A.3    Kugel, J.F.4
  • 21
    • 0037073077 scopus 로고    scopus 로고
    • Promoter clearance and escape in prokaryotes
    • Hsu L.M. Promoter clearance and escape in prokaryotes. Biochim. Biophys. Acta 1577 (2002) 191-207
    • (2002) Biochim. Biophys. Acta , vol.1577 , pp. 191-207
    • Hsu, L.M.1
  • 22
    • 0001210090 scopus 로고
    • Interactions of the RNA polymerase of bacteriophage T7 with its promoter during binding and initiation of transcription
    • Ikeda R.A., and Richardson C.C. Interactions of the RNA polymerase of bacteriophage T7 with its promoter during binding and initiation of transcription. Proc. Natl. Acad. Sci. USA 83 (1986) 3614-3618
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 3614-3618
    • Ikeda, R.A.1    Richardson, C.C.2
  • 23
    • 0023654344 scopus 로고
    • Interactions of a proteolytically nicked RNA polymerase of bacteriophage T7 with its promoter
    • Ikeda R.A., and Richardson C.C. Interactions of a proteolytically nicked RNA polymerase of bacteriophage T7 with its promoter. J. Biol. Chem. 262 (1987) 3800-3808
    • (1987) J. Biol. Chem. , vol.262 , pp. 3800-3808
    • Ikeda, R.A.1    Richardson, C.C.2
  • 24
    • 0032527832 scopus 로고    scopus 로고
    • Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme
    • Jeruzalmi D., and Steitz T.A. Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme. EMBO J. 17 (1998) 4101-4113
    • (1998) EMBO J. , vol.17 , pp. 4101-4113
    • Jeruzalmi, D.1    Steitz, T.A.2
  • 25
    • 0030999232 scopus 로고    scopus 로고
    • Kinetic mechanism of transcription initiation by bacteriophage T7 RNA polymerase
    • Jia Y., and Patel S.S. Kinetic mechanism of transcription initiation by bacteriophage T7 RNA polymerase. Biochemistry 36 (1997) 4223-4232
    • (1997) Biochemistry , vol.36 , pp. 4223-4232
    • Jia, Y.1    Patel, S.S.2
  • 26
    • 0029846428 scopus 로고    scopus 로고
    • Equilibrium and stopped-flow kinetic studies of interaction between T7 RNA polymerase and its promoters measured by protein and 2-aminopurine fluorescence changes
    • Jia Y., Kumar A., and Patel S.S. Equilibrium and stopped-flow kinetic studies of interaction between T7 RNA polymerase and its promoters measured by protein and 2-aminopurine fluorescence changes. J. Biol. Chem. 271 (1996) 30451-30458
    • (1996) J. Biol. Chem. , vol.271 , pp. 30451-30458
    • Jia, Y.1    Kumar, A.2    Patel, S.S.3
  • 27
    • 33751212468 scopus 로고    scopus 로고
    • Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism
    • Kapanidis A.N., Margeat E., Ho S.O., Kortkhonjia E., Weiss S., and Ebright R.H. Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism. Science 314 (2006) 1144-1147
    • (2006) Science , vol.314 , pp. 1144-1147
    • Kapanidis, A.N.1    Margeat, E.2    Ho, S.O.3    Kortkhonjia, E.4    Weiss, S.5    Ebright, R.H.6
  • 28
    • 0020490646 scopus 로고
    • RNA polymerase: correlation between transcript length, abortive product synthesis, and formation of a stable ternary complex
    • Kinsella L., Hsu C.Y., Schulz W., and Dennis D. RNA polymerase: correlation between transcript length, abortive product synthesis, and formation of a stable ternary complex. Biochemistry 21 (1982) 2719-2723
    • (1982) Biochemistry , vol.21 , pp. 2719-2723
    • Kinsella, L.1    Hsu, C.Y.2    Schulz, W.3    Dennis, D.4
  • 29
    • 0024974056 scopus 로고
    • RNA chain initiation by Escherichia coli RNA polymerase. Structural transitions of the enzyme in early ternary complexes
    • Krummel B., and Chamberlin M.J. RNA chain initiation by Escherichia coli RNA polymerase. Structural transitions of the enzyme in early ternary complexes. Biochemistry 28 (1989) 7829-7842
    • (1989) Biochemistry , vol.28 , pp. 7829-7842
    • Krummel, B.1    Chamberlin, M.J.2
  • 30
    • 22144492905 scopus 로고    scopus 로고
    • Accurate FRET measurements within single diffusing biomolecules using alternating-laser excitation
    • Lee N.K., Kapanidis A.N., Wang Y., Michalet X., Mukhopadhyay J., Ebright R.H., and Weiss S. Accurate FRET measurements within single diffusing biomolecules using alternating-laser excitation. Biophys. J. 88 (2005) 2939-2953
    • (2005) Biophys. J. , vol.88 , pp. 2939-2953
    • Lee, N.K.1    Kapanidis, A.N.2    Wang, Y.3    Michalet, X.4    Mukhopadhyay, J.5    Ebright, R.H.6    Weiss, S.7
  • 31
    • 0037169496 scopus 로고    scopus 로고
    • Promoter clearance by T7 RNA polymerase. Initial bubble collapse and transcript dissociation monitored by base analog fluorescence
    • Liu C., and Martin C.T. Promoter clearance by T7 RNA polymerase. Initial bubble collapse and transcript dissociation monitored by base analog fluorescence. J. Biol. Chem. 277 (2002) 2725-2731
    • (2002) J. Biol. Chem. , vol.277 , pp. 2725-2731
    • Liu, C.1    Martin, C.T.2
  • 32
    • 0037044758 scopus 로고    scopus 로고
    • Major conformational changes occur during the transition from an initiation complex to an elongation complex by T7 RNA polymerase
    • Ma K., Temiakov D., Jiang M., Anikin M., and McAllister W.T. Major conformational changes occur during the transition from an initiation complex to an elongation complex by T7 RNA polymerase. J. Biol. Chem. 277 (2002) 43206-43215
    • (2002) J. Biol. Chem. , vol.277 , pp. 43206-43215
    • Ma, K.1    Temiakov, D.2    Jiang, M.3    Anikin, M.4    McAllister, W.T.5
  • 33
    • 29144450914 scopus 로고    scopus 로고
    • Probing conformational changes in T7 RNA polymerase during initiation and termination by using engineered disulfide linkages
    • Ma K., Temiakov D., Anikin M., and McAllister W.T. Probing conformational changes in T7 RNA polymerase during initiation and termination by using engineered disulfide linkages. Proc. Natl. Acad. Sci. USA 102 (2005) 17612-17617
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 17612-17617
    • Ma, K.1    Temiakov, D.2    Anikin, M.3    McAllister, W.T.4
  • 34
    • 1842383693 scopus 로고
    • Rate-limiting steps in RNA chain initiation
    • McClure W.R. Rate-limiting steps in RNA chain initiation. Proc. Natl. Acad. Sci. USA 77 (1980) 5634-5638
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 5634-5638
    • McClure, W.R.1
  • 35
    • 27644560257 scopus 로고    scopus 로고
    • Sigma and RNA polymerase: an on-again, off-again relationship?
    • Mooney R.A., Darst S.A., and Landick R. Sigma and RNA polymerase: an on-again, off-again relationship?. Mol. Cell 20 (2005) 335-345
    • (2005) Mol. Cell , vol.20 , pp. 335-345
    • Mooney, R.A.1    Darst, S.A.2    Landick, R.3
  • 36
    • 0037067648 scopus 로고    scopus 로고
    • Structural transitions mediating transcription initiation by T7 RNA polymerase
    • Mukherjee S., Brieba L.G., and Sousa R. Structural transitions mediating transcription initiation by T7 RNA polymerase. Cell 110 (2002) 81-91
    • (2002) Cell , vol.110 , pp. 81-91
    • Mukherjee, S.1    Brieba, L.G.2    Sousa, R.3
  • 37
    • 0032168436 scopus 로고    scopus 로고
    • Rod models of DNA: sequence-dependent anisotropic elastic modelling of local bending phenomena
    • Munteanu M.G., Vlahovicek K., Parthasarathy S., Simon I., and Pongor S. Rod models of DNA: sequence-dependent anisotropic elastic modelling of local bending phenomena. Trends Biochem. Sci. 23 (1998) 341-347
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 341-347
    • Munteanu, M.G.1    Vlahovicek, K.2    Parthasarathy, S.3    Simon, I.4    Pongor, S.5
  • 38
    • 27644514163 scopus 로고    scopus 로고
    • Repetitive shuttling of a motor protein on DNA
    • Myong S., Rasnik I., Joo C., Lohman T.M., and Ha T. Repetitive shuttling of a motor protein on DNA. Nature 437 (2005) 1321-1325
    • (2005) Nature , vol.437 , pp. 1321-1325
    • Myong, S.1    Rasnik, I.2    Joo, C.3    Lohman, T.M.4    Ha, T.5
  • 39
    • 0033586735 scopus 로고    scopus 로고
    • Studies of contacts between T7 RNA polymerase and its promoter reveal features in common with multisubunit RNA polymerases
    • Place C., Oddos J., Buc H., McAllister W.T., and Buckle M. Studies of contacts between T7 RNA polymerase and its promoter reveal features in common with multisubunit RNA polymerases. Biochemistry 38 (1999) 4948-4957
    • (1999) Biochemistry , vol.38 , pp. 4948-4957
    • Place, C.1    Oddos, J.2    Buc, H.3    McAllister, W.T.4    Buckle, M.5
  • 40
    • 0742324525 scopus 로고    scopus 로고
    • DNA-binding orientation and domain conformation of the E. coli rep helicase monomer bound to a partial duplex junction: single-molecule studies of fluorescently labeled enzymes
    • Rasnik I., Myong S., Cheng W., Lohman T.M., and Ha T. DNA-binding orientation and domain conformation of the E. coli rep helicase monomer bound to a partial duplex junction: single-molecule studies of fluorescently labeled enzymes. J. Mol. Biol. 336 (2004) 395-408
    • (2004) J. Mol. Biol. , vol.336 , pp. 395-408
    • Rasnik, I.1    Myong, S.2    Cheng, W.3    Lohman, T.M.4    Ha, T.5
  • 41
    • 33751218319 scopus 로고    scopus 로고
    • Abortive initiation and productive initiation by RNA polymerase involve DNA scrunching
    • Revyakin A., Liu C., Ebright R.H., and Strick T.R. Abortive initiation and productive initiation by RNA polymerase involve DNA scrunching. Science 314 (2006) 1139-1143
    • (2006) Science , vol.314 , pp. 1139-1143
    • Revyakin, A.1    Liu, C.2    Ebright, R.H.3    Strick, T.R.4
  • 42
    • 34248664689 scopus 로고    scopus 로고
    • Dynamic structural rearrangements between DNA binding modes of E. coli SSB protein
    • Roy R., Kozlov A.G., Lohman T.M., and Ha T. Dynamic structural rearrangements between DNA binding modes of E. coli SSB protein. J. Mol. Biol. 369 (2007) 1244-1257
    • (2007) J. Mol. Biol. , vol.369 , pp. 1244-1257
    • Roy, R.1    Kozlov, A.G.2    Lohman, T.M.3    Ha, T.4
  • 43
    • 33747621427 scopus 로고    scopus 로고
    • Visualizing polynucleotide polymerase machines at work
    • Steitz T.A. Visualizing polynucleotide polymerase machines at work. EMBO J. 25 (2006) 3458-3468
    • (2006) EMBO J. , vol.25 , pp. 3458-3468
    • Steitz, T.A.1
  • 44
    • 0023102647 scopus 로고
    • A stressed intermediate in the formation of stably initiated RNA chains at the Escherichia coli lac UV5 promoter
    • Straney D.C., and Crothers D.M. A stressed intermediate in the formation of stably initiated RNA chains at the Escherichia coli lac UV5 promoter. J. Mol. Biol. 193 (1987) 267-278
    • (1987) J. Mol. Biol. , vol.193 , pp. 267-278
    • Straney, D.C.1    Crothers, D.M.2
  • 46
    • 33645896417 scopus 로고    scopus 로고
    • Rapid binding of T7 RNA polymerase is followed by simultaneous bending and opening of the promoter DNA
    • Tang G.Q., and Patel S.S. Rapid binding of T7 RNA polymerase is followed by simultaneous bending and opening of the promoter DNA. Biochemistry 45 (2006) 4947-4956
    • (2006) Biochemistry , vol.45 , pp. 4947-4956
    • Tang, G.Q.1    Patel, S.S.2
  • 47
    • 33645910849 scopus 로고    scopus 로고
    • T7 RNA polymerase-induced bending of promoter DNA is coupled to DNA opening
    • Tang G.Q., and Patel S.S. T7 RNA polymerase-induced bending of promoter DNA is coupled to DNA opening. Biochemistry 45 (2006) 4936-4946
    • (2006) Biochemistry , vol.45 , pp. 4936-4946
    • Tang, G.Q.1    Patel, S.S.2
  • 48
    • 28944439650 scopus 로고    scopus 로고
    • Extended upstream A-T sequence increases T7 promoter strength
    • Tang G.Q., Bandwar R.P., and Patel S.S. Extended upstream A-T sequence increases T7 promoter strength. J. Biol. Chem. 280 (2005) 40707-40713
    • (2005) J. Biol. Chem. , vol.280 , pp. 40707-40713
    • Tang, G.Q.1    Bandwar, R.P.2    Patel, S.S.3
  • 49
    • 0034687683 scopus 로고    scopus 로고
    • The specificity loop of T7 RNA polymerase interacts first with the promoter and then with the elongating transcript, suggesting a mechanism for promoter clearance
    • Temiakov D., Mentesana P.E., Ma K., Mustaev A., Borukhov S., and McAllister W.T. The specificity loop of T7 RNA polymerase interacts first with the promoter and then with the elongating transcript, suggesting a mechanism for promoter clearance. Proc. Natl. Acad. Sci. USA 97 (2000) 14109-14114
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 14109-14114
    • Temiakov, D.1    Mentesana, P.E.2    Ma, K.3    Mustaev, A.4    Borukhov, S.5    McAllister, W.T.6
  • 50
    • 4944260681 scopus 로고    scopus 로고
    • Topological and conformational analysis of the initiation and elongation complex of t7 RNA polymerase suggests a new twist
    • Theis K., Gong P., and Martin C.T. Topological and conformational analysis of the initiation and elongation complex of t7 RNA polymerase suggests a new twist. Biochemistry 43 (2004) 12709-12715
    • (2004) Biochemistry , vol.43 , pp. 12709-12715
    • Theis, K.1    Gong, P.2    Martin, C.T.3
  • 51
    • 33847073417 scopus 로고    scopus 로고
    • Structural confirmation of a bent and open model for the initiation complex of T7 RNA polymerase
    • Turingan R.S., Liu C., Hawkins M.E., and Martin C.T. Structural confirmation of a bent and open model for the initiation complex of T7 RNA polymerase. Biochemistry 46 (2007) 1714-1723
    • (2007) Biochemistry , vol.46 , pp. 1714-1723
    • Turingan, R.S.1    Liu, C.2    Hawkins, M.E.3    Martin, C.T.4
  • 52
    • 34249681855 scopus 로고    scopus 로고
    • Twisted or shifted? Fluorescence measurements of late intermediates in transcription initiation by t7 RNA polymerase
    • Turingan R.S., Theis K., and Martin C.T. Twisted or shifted? Fluorescence measurements of late intermediates in transcription initiation by t7 RNA polymerase. Biochemistry 46 (2007) 6165-6168
    • (2007) Biochemistry , vol.46 , pp. 6165-6168
    • Turingan, R.S.1    Theis, K.2    Martin, C.T.3
  • 53
    • 0034602929 scopus 로고    scopus 로고
    • Evidence for DNA bending at the T7 RNA polymerase promoter
    • Ujvari A., and Martin C.T. Evidence for DNA bending at the T7 RNA polymerase promoter. J. Mol. Biol. 295 (2000) 1173-1184
    • (2000) J. Mol. Biol. , vol.295 , pp. 1173-1184
    • Ujvari, A.1    Martin, C.T.2
  • 54
    • 0037112082 scopus 로고    scopus 로고
    • Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase
    • Yin Y.W., and Steitz T.A. Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase. Science 298 (2002) 1387-1395
    • (2002) Science , vol.298 , pp. 1387-1395
    • Yin, Y.W.1    Steitz, T.A.2
  • 55
    • 0037123763 scopus 로고    scopus 로고
    • Views of transcription initiation
    • Young B.A., Gruber T.M., and Gross C.A. Views of transcription initiation. Cell 109 (2002) 417-420
    • (2002) Cell , vol.109 , pp. 417-420
    • Young, B.A.1    Gruber, T.M.2    Gross, C.A.3


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