Capsaicin receptor TRPV1

Brain and Nerve

Volumn 60, Issue 5, 2008, Pages 493-501

  Tominaga, Makoto ^a  

^a NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

Nociception; TRP channels; TRPAI; TRPVI

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; ENDOTHELIN 1; NEUROKININ 1 RECEPTOR; NITRIC OXIDE; PROSTAGLANDIN; SUBSTANCE P; VANILLOID RECEPTOR 1;

ARTICLE; COLD SENSITIVITY; ENTERITIS; HETEROLOGOUS EXPRESSION; INFLAMMATION; IRRITABLE COLON; MOUSE; NOCICEPTION; NONHUMAN; NONOBESE DIABETIC MOUSE; PAIN; STOMACH PROTECTION;

ANALGESICS; ANIMALS; CLONING, MOLECULAR; DRUG DESIGN; HUMANS; MICE; PAIN; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TRPV CATION CHANNELS;

EID: 44449091223     PISSN: 00068969     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Montell C, Rubin GM: Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction. Neuron 2: 1313-1323, 1989
2. Montell C: The TRP Superfamily of Cation Channels. Sci STKE 2005: re3, 2005
3. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, et al: The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389: 816-824, 1997
4. Bandell M, Macpherson LJ, Patapoutian A: From chills to chilis: mechanisms for thermosensation and chemesthesis via thermoTRPs. Curr Opin Neurobiol 17: 490-497, 2007
5. Cortright DN, Krause JE, Broom DC: TRP channels and pain. Biochim Biophys Acta 1772: 978-988, 2007
6. Levine JD, Alessandri-Haber N: TRP channels: targets for the relief of pain. Biochim Biophys Acta 1772: 989-1003, 2007
7. Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, et al: The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21: 531-543, 1998
8. Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, et al: Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288: 241-242, 2000
9. Binshtok AM, Bean BP, Woolf CJ: Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers. Nature 449: 607-610, 2007
10. Kim S, Kang C, Shin CY, Hwang SW, Yang YD, et al: TRPV1 recapitulates native capsaicin receptor in sensory neurons in association with Fas-associated factor 1. J Neurosci 26: 2403-2412, 2006
11. Jordt SE, Julius D: Molecular basis for species-specific sensitivity to "hot" chili peppers. Cell 108: 421-430, 2002
12. Jordt S E, Tominaga M, Julius D: Acid potentiation of the capsaicin receptor determined by a key extracellular site. Proc Natl Acad Sci U S A 97: 8134-8139, 2000
13. Voets T, Droogmans G, Wissenbach U, Janssens A, Flockrzi V, et al: The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels. Nature 430: 748-754, 2004
14. Yoshida T, Inoue R, Morii T, Takahashi N, Yamamoto S, et al: Nitric oxide activates TRP channels by cysteine S-nitrosylation. Nat Chem Biol 2: 596-607, 2006
15. Hinman A, Chuang HH, Bautista DM, Julius D: TRP channel activation by reversible covalent modification. Proc Natl Acad Sci U S A 103: 19564-19568, 2006
16. Macpherson LJ, Dubin AE, Evans MJ, Marr F, Schultz PG, et al: Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature 445: 541-545, 2007
17. Salazar H, Llorente I, Jara-Oseguera A, Garciavillegas R, Munari M, et al: A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic. Nat Neurosci 11: 255-261, 2008
18. Tominaga M, Caterina MJ: Thermosensation and pain. J Neurobiol 61: 3-12, 2004
19. Chuang HH, Prescott ED, Kong H, Shield S, Jordt SE, et al: Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns (4, 5) P2-mediated inhibition. Nature 411: 957-962, 2001
20. Lukacs V, Thyagarajan B, Varnai P, Balla A, Balla T, et al: Dual regulation of TRPV1 by phosphoinositides. J Neurosci 27: 7070-7080, 2007
21. Shin J, Cho H, Hwang SW: Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia. Proc Natl Acad Sci U S A 99: 10150-10155, 2002
22. Zhang H, Cang CL, Kawasaki Y, Liang LL, Zhang YQ, et al: Neurokinin-1 receptor enhances TRPV1 activity in primary sensory neurons via PKCepsilon: a novel pathway for heat hyperalgesia. J Neurosci 27: 12067-12077, 2007
23. 2+ response via activation of endothelin a receptor in a protein kinase Cepsilon-dependent manner in dorsal root ganglion neurons. Neuroscience 137: 949-960, 2006
24. Nozawa Y, Nishihara K, Yamamoto A, Nakano M, Ajioka H, et al: Distribution and characterization of vanilloid receptors in the rat stomach. Neurosci Lett 309: 33-36, 2001
25. Horie S, Yamamoto H, Michael GJ, Uchida M, Belai A, et al: Protective role of vanilloid receptor type 1 in HCl-induced gastric mucosal lesions in rats. Scand J Gastroenterol 39: 303-312, 2004
26. Szolcsányi J, Barthó L: Capsaicin-sensitive afferents and their role in gastroprotection: an update. J Physiol Paris 95: 181-188, 2001
27. Yiangou Y, Facer P, Dyer NH, Chan CL, Knowles C, et al: Vanilloid receptor 1 immunoreactivity in inflamed human bowel. Lancet 357: 1338-1339, 2001
28. Sugiuar T, Bielefeldt K, Gebhart GF: TRPV1 function in mouse colon sensory neurons is enhanced by metabotropic 5-hydroxytryptamine receptor activation. J Neurosci 24: 9521-9530, 2004
29. Razavi R, Chan Y, Afifiyan FN, Liu XJ, Wan X, et al: TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes. Cell 127: 1123-1135, 2006
30. Montell C, Caterina MJ: Thermoregulation: Channels that are cool to the core. Curr Biol 17: R885-887, 2007
31. Story GM, Peier AM, Reeve AJ, Eid SR, Mosbacher J, et al: ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 112: 819-829, 2003
32. Obata K, Katsura H, Mizushima T, Yamanaka H, Kobayashi K, et al: TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury. J Clin Invest 115: 2393-2401, 2005
33. Dai Y, Wang S, Tominaga M, Yamamoto S, Fukuoka T, et al: Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain. J Clin Invest 117: 1979-1987, 2007
34. Dai Y, Moriyama T, Higashi T, Togashi K, Kobayashi K, et al: Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain. J Neurosci 24: 4293-4299, 2004